Development Level

Tdark 53 | 7,003
Tbio 43 | 10,625
Tchem 24 | 1,890
Tclin 8 | 602

IMPC Phenotype

decreased body weight 3 | 174
decreased circulating creatini... 3 | 31
increased mean corpuscular hem... 3 | 93
preweaning lethality, complete... 3 | 633
abnormal coat-hair pigmentatio... 2 | 54
decreased circulating fructosa... 2 | 31
decreased lumbar vertebrae num... 2 | 62
decreased mature B cell number 2 | 25
increased grip strength 2 | 83
increased leukocyte cell numbe... 2 | 37
male infertility 2 | 62
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal cornea morphology 1 | 24
abnormal digit morphology 1 | 13
abnormal femur morphology 1 | 14
abnormal hair texture 1 | 4
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
corneal opacity 1 | 25
decreased B cell number 1 | 30
decreased CD4-positive, CD25-p... 1 | 24
decreased Ly6C low monocyte nu... 1 | 23
decreased NK T cell number 1 | 28
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating insulin ... 1 | 75
decreased circulating iron lev... 1 | 25
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
fused cornea and lens 1 | 4
fused phalanges 1 | 1
fusion of vertebral arches 1 | 7
impaired pupillary reflex 1 | 14
increased IgG1 level 1 | 1
increased Ly6C high monocyte n... 1 | 12
increased T cell number 1 | 15
increased blood urea nitrogen ... 1 | 44
increased circulating potassiu... 1 | 31
increased effector memory CD4-... 1 | 15
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 91
increased red blood cell distr... 1 | 21
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
persistence of hyaloid vascula... 1 | 22
preweaning lethality, incomple... 1 | 260
vertebral fusion 1 | 23

Disease

osteosarcoma 54 | 7,933
ovarian cancer 46 | 8,491
psoriasis 36 | 6,685
Cancer 35 | 2,346
medulloblastoma, large-cell 32 | 6,234
lung cancer 30 | 4,473
interstitial cystitis 27 | 2,299
glioblastoma 26 | 5,572
atypical teratoid / rhabdoid tumor 21 | 4,369
lung carcinoma 20 | 2,844
Multiple myeloma 19 | 1,327
non-small cell lung cancer 19 | 2,798
pancreatic cancer 19 | 2,300
Breast cancer 18 | 3,098
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
lung adenocarcinoma 18 | 2,714
pilocytic astrocytoma 18 | 3,086
ulcerative colitis 18 | 2,087
Waldenstrons macroglobulinemia 17 | 764
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,956
oligodendroglioma 17 | 2,849
Carcinoma 16 | 2,147
invasive ductal carcinoma 16 | 2,950
juvenile dermatomyositis 16 | 1,189
subependymal giant cell astrocytoma 16 | 2,287
ependymoma 15 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
tuberculosis 15 | 1,563
cutaneous lupus erythematosus 14 | 1,056
primary Sjogren syndrome 14 | 788
medulloblastoma 13 | 1,524
primary pancreatic ductal adenocarcinoma 13 | 1,271
periodontitis 12 | 269
primitive neuroectodermal tumor 12 | 3,031
Pick disease 11 | 1,893
astrocytic glioma 11 | 2,241
chronic lymphosyte leukemia 11 | 232
diabetes mellitus 11 | 1,663
astrocytoma 10 | 1,493
cystic fibrosis 10 | 1,670
pediatric high grade glioma 10 | 2,712
IGA Glomerulonephritis 9 | 454
Rheumatoid Arthritis 9 | 1,170
Wiskott-Aldrich syndrome 9 | 27
adult high grade glioma 9 | 2,148
colon cancer 9 | 1,475
dermatomyositis 9 | 966
ductal carcinoma in situ 9 | 1,745
breast carcinoma 8 | 1,614
esophageal adenocarcinoma 8 | 737
malignant mesothelioma 8 | 3,163
mucosa-associated lymphoid tissue lymphoma 8 | 480
tuberculosis and treatment for 6 months 8 | 686
Amebiasis 7 | 22
Blastic phase chronic myeloid leukemia 7 | 58
Chronic Myelocytic Leukemia Accelerated Phase 7 | 59
Leukemia 7 | 88
group 4 medulloblastoma 7 | 1,875
sonic hedgehog group medulloblastoma 7 | 1,482
Alzheimer's disease 6 | 644
Kidney disease 6 | 397
Parkinson's disease 6 | 364
acute quadriplegic myopathy 6 | 1,157
cystic fibrosis and chronic rhinosinusitis 6 | 213
gastric carcinoma 6 | 832
pancreatic carcinoma 6 | 567
Arthritis 5 | 248
Chronic phase chronic myeloid leukemia 5 | 45
Down syndrome 5 | 548
Duchenne muscular dystrophy 5 | 602
Intellectual disability 5 | 573
Lymphoma 5 | 57
Mammary Neoplasms 5 | 410
Neoplasm Invasiveness 5 | 127
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 5 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 5 | 47
Vascular disease 5 | 281
group 3 medulloblastoma 5 | 2,254
non-small cell lung carcinoma 5 | 413
spina bifida 5 | 1,064
Animal Mammary Neoplasms 4 | 135
Asthma 4 | 349
Cherubism 4 | 14
HIV Infections 4 | 99
Liver carcinoma 4 | 217
Lung Neoplasms 4 | 171
Mammary Neoplasms, Experimental 4 | 149
Multiple Sclerosis 4 | 498
Neoplasm Metastasis 4 | 138
Prostatic Neoplasms 4 | 471
Squamous cell carcinoma 4 | 96
Stomach Neoplasms 4 | 282
acute myeloid leukemia 4 | 785
atypical teratoid/rhabdoid tumor 4 | 1,095
chronic lymphocytic leukemia 4 | 244
non primary Sjogren syndrome sicca 4 | 840
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pituitary cancer 4 | 1,972
posterior fossa group A ependymoma 4 | 1,511
Schizophrenia 3 | 503

Tissue

Blood and immune system 113 | 17,994
Digestive Tract 113 | 18,472
Female tissues 113 | 18,646
Respiratory system 113 | 17,483
Liver and Pancreas 112 | 18,135
Skin and soft tissues 112 | 18,114
Urinary Tract 112 | 18,443
Cardiovascular System 111 | 17,957
Endocrine System 110 | 18,511
Nervous System 110 | 18,560
Male tissues 108 | 17,968

Target Family

Non-IDG 102 | 11,969
Kinase 18 | 634
Enzyme 8 | 4,146

GO Process

Fc-gamma receptor signaling pa... 128 | 128
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WAS/WASL-interacting protein family member 1 WIPF1 Tbio Non-IDG -2.00605 100.9 97
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.39396 233.2 634
Proto-oncogene vav VAV1 Tchem Non-IDG -2.64007 465.9 479
Guanine nucleotide exchange factor VAV2 VAV2 Tbio Non-IDG -1.78476 58.3 173
Ig lambda-6 chain C region IGLC6 Tdark Non-IDG -1.81183 228.7 0
Wiskott-Aldrich syndrome protein family member 2 WASF2 Tbio Non-IDG -2.86162 683.7 211
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.87449 73.5 395
NCK-interacting protein with SH3 domain NCKIPSD Tbio Non-IDG -0.98081 14.9 92
Heat shock protein HSP 90-alpha HSP90AA1 Tchem Non-IDG -3.28941 4395.5 921
Tyrosine-protein kinase SYK SYK Tchem Kinase -3.11789 1349.3 1026