Development Level

Tdark 56 | 6,593
Tbio 48 | 11,651
Tchem 20 | 1,388
Tclin 9 | 612

IMPC Phenotype

preweaning lethality, complete... 9 | 979
decreased body weight 3 | 161
decreased circulating creatini... 3 | 39
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal digit morphology 2 | 10
abnormal retina morphology 2 | 71
decreased circulating fructosa... 2 | 30
decreased circulating serum al... 2 | 82
decreased hemoglobin content 2 | 68
embryonic lethality prior to t... 2 | 278
increased blood urea nitrogen ... 2 | 48
increased grip strength 2 | 41
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased neutrophil cell numb... 2 | 46
increased spleen weight 2 | 10
increased total body fat amoun... 2 | 134
male infertility 2 | 123
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal hair texture 1 | 4
abnormal heart morphology 1 | 162
abnormal maxilla morphology 1 | 17
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal stomach morphology 1 | 10
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased IgG3 level 1 | 1
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged kidney 1 | 14
fused cornea and lens 1 | 5
fused phalanges 1 | 1
fusion of vertebral arches 1 | 7
impaired pupillary reflex 1 | 26
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased circulating alkaline... 1 | 122
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
short tibia 1 | 97
small testis 1 | 58
thin ventricular wall 1 | 24
vertebral fusion 1 | 23

Disease

osteosarcoma 54 | 7,950
Carcinoma 53 | 11,493
ovarian cancer 47 | 8,520
Cancer 37 | 2,499
psoriasis 36 | 6,694
medulloblastoma, large-cell 32 | 6,241
lung cancer 31 | 4,740
glioblastoma 28 | 5,792
interstitial cystitis 28 | 2,312
Breast cancer 22 | 3,578
atypical teratoid / rhabdoid tumor 22 | 5,112
lung carcinoma 21 | 2,843
non-small cell lung cancer 21 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
pancreatic cancer 19 | 2,398
tuberculosis 19 | 2,010
Astrocytoma, Pilocytic 18 | 3,081
Multiple myeloma 18 | 1,332
ependymoma 18 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
lung adenocarcinoma 18 | 2,716
ulcerative colitis 18 | 1,819
Kidney cancer 17 | 2,613
Waldenstrons macroglobulinemia 17 | 765
invasive ductal carcinoma 17 | 2,951
oligodendroglioma 17 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
juvenile dermatomyositis 16 | 1,187
subependymal giant cell astrocytoma 16 | 2,287
primary Sjogren syndrome 15 | 735
cutaneous lupus erythematosus 14 | 1,057
adult high grade glioma 13 | 3,801
group 3 medulloblastoma 13 | 4,104
periodontitis 13 | 293
Schizophrenia 12 | 1,160
diabetes mellitus 12 | 1,728
group 4 medulloblastoma 12 | 1,855
primitive neuroectodermal tumor 12 | 3,035
Autosomal recessive predisposition 11 | 1,442
Liver Cirrhosis, Experimental 11 | 769
Pick disease 11 | 1,894
astrocytic glioma 11 | 2,597
cystic fibrosis 11 | 1,696
primary pancreatic ductal adenocarcinoma 11 | 1,109
Rheumatoid arthritis 10 | 1,191
Wiskott-Aldrich syndrome 10 | 30
astrocytoma 10 | 1,146
chronic lymphosyte leukemia 10 | 204
colon cancer 10 | 1,478
Intellectual disability 9 | 1,016
breast carcinoma 9 | 1,638
dermatomyositis 9 | 966
ductal carcinoma in situ 9 | 1,745
mucosa-associated lymphoid tissue lymphoma 9 | 484
Immunologic Deficiency Syndromes 8 | 113
esophageal adenocarcinoma 8 | 737
malignant mesothelioma 8 | 3,232
Arthritis 7 | 290
Bipolar Disorder 7 | 666
Blastic phase chronic myeloid leukemia 7 | 58
Chronic Myelocytic Leukemia Accelerated Phase 7 | 59
Kidney disease 7 | 430
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
pediatric high grade glioma 7 | 1,064
Leukemia 6 | 104
Liver cancer 6 | 604
Melanoma 6 | 711
Parkinson's disease 6 | 392
Thrombocytopenia 6 | 197
acute quadriplegic myopathy 6 | 1,158
cystic fibrosis and chronic rhinosinusitis 6 | 214
gastric carcinoma 6 | 807
pancreatic carcinoma 6 | 562
Amebiasis 5 | 21
Breast Neoplasms 5 | 445
Chronic Lymphocytic Leukemia 5 | 262
Chronic otitis media 5 | 52
Cognitive delay 5 | 608
Depressive disorder 5 | 409
Down syndrome 5 | 499
Duchenne muscular dystrophy 5 | 601
Dull intelligence 5 | 645
Fatigue 5 | 182
Global developmental delay 5 | 608
Low intelligence 5 | 645
Mammary Neoplasms 5 | 425
Mammary Neoplasms, Experimental 5 | 154
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Neoplasm Invasiveness 5 | 161
Neoplasm Metastasis 5 | 168
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 5 | 45
Poor school performance 5 | 645
Recurrent respiratory infections 5 | 141
Seizures 5 | 596
Stomach Neoplasms 5 | 300
Vascular disease 5 | 319
ear infection chronic 5 | 52
spina bifida 5 | 1,074

Tissue

Blood and immune system 71 | 16,909
Cardiovascular System 71 | 15,192
Digestive Tract 71 | 17,369
Endocrine System 71 | 18,159
Male tissues 71 | 17,142
Nervous System 71 | 16,725
Respiratory system 71 | 16,393
Skin and soft tissues 71 | 17,230
Urinary Tract 71 | 16,678
Female tissues 70 | 17,400
Liver and Pancreas 70 | 16,750

Target Family

Non-IDG 107 | 12,091
Kinase 18 | 634
Enzyme 8 | 4,145

GO Process

Fc-gamma receptor signaling pa... 133 | 133
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Cytoplasmic FMR1-interacting protein 1 CYFIP1 Tbio Non-IDG -1.46134 28.5 64
T-cell surface glycoprotein CD3 zeta chain CD247 Tbio Non-IDG -2.61157 386.3 882
Serine/threonine-protein kinase PAK 1 PAK1 Tchem Kinase -2.29299 237.8 1060
Tyrosine-protein kinase SYK SYK Tchem Kinase -3.14835 1437.4 1136
Guanine nucleotide exchange factor VAV3 VAV3 Tbio Non-IDG -1.82116 74.0 249
Low affinity immunoglobulin gamma Fc region receptor II-b FCGR2B Tbio Non-IDG -2.61667 619.4 476
Cytoplasmic protein NCK1 NCK1 Tbio Non-IDG -2.25032 186.5 398
Protein BRICK1 BRK1 Tbio Non-IDG -1.43779 28.1 63
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.94674 87.1 452