Development Level

Tbio 77 | 11,445
Tdark 58 | 6,588
Tchem 36 | 1,598
Tclin 11 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 4 | 499
abnormal bone structure 3 | 187
decreased body weight 3 | 161
decreased circulating creatini... 3 | 39
abnormal lens morphology 2 | 81
decreased circulating choleste... 2 | 93
decreased circulating sodium l... 2 | 22
decreased heart left ventricle... 2 | 28
decreased hemoglobin content 2 | 68
decreased vertical activity 2 | 208
increased blood urea nitrogen ... 2 | 48
increased circulating free fat... 2 | 20
increased erythrocyte cell num... 2 | 39
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal cornea morphology 1 | 31
abnormal digit morphology 1 | 10
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal skin condition 1 | 6
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased IgG3 level 1 | 1
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating magnesiu... 1 | 13
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased thermal nociceptive ... 1 | 2
embryonic lethality prior to t... 1 | 278
increased CD4-positive, alpha ... 1 | 4
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small testis 1 | 58
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56

Disease

ovarian cancer 87 | 8,520
Carcinoma 75 | 11,493
osteosarcoma 70 | 7,950
lung cancer 62 | 4,740
psoriasis 56 | 6,694
Cancer 55 | 2,499
glioblastoma 55 | 5,792
Multiple myeloma 44 | 1,332
medulloblastoma, large-cell 39 | 6,241
atypical teratoid / rhabdoid tumor 35 | 5,112
subependymal giant cell astrocytoma 30 | 2,287
ependymoma 29 | 4,679
non-small cell lung cancer 29 | 2,890
Breast cancer 28 | 3,578
adult high grade glioma 27 | 3,801
Kidney cancer 24 | 2,613
interstitial cystitis 24 | 2,312
invasive ductal carcinoma 23 | 2,951
lung carcinoma 23 | 2,843
pancreatic cancer 23 | 2,398
Astrocytoma, Pilocytic 22 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
malignant mesothelioma 22 | 3,232
oligodendroglioma 22 | 2,850
Waldenstrons macroglobulinemia 21 | 765
group 3 medulloblastoma 21 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
lung adenocarcinoma 21 | 2,716
ulcerative colitis 21 | 1,819
Pick disease 20 | 1,894
astrocytic glioma 20 | 2,597
astrocytoma 19 | 1,146
dermatomyositis 19 | 966
diabetes mellitus 19 | 1,728
group 4 medulloblastoma 19 | 1,855
primitive neuroectodermal tumor 19 | 3,035
tuberculosis 18 | 2,010
HIV Infections 16 | 102
cutaneous lupus erythematosus 16 | 1,057
Schizophrenia 15 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
juvenile dermatomyositis 15 | 1,187
Rheumatoid arthritis 14 | 1,191
primary pancreatic ductal adenocarcinoma 14 | 1,109
colon cancer 13 | 1,478
primary Sjogren syndrome 13 | 735
Arthritis 12 | 290
acute myeloid leukemia 12 | 783
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Breast Neoplasms 11 | 445
Epilepsy 11 | 792
Mammary Neoplasms 11 | 425
periodontitis 11 | 293
Autosomal recessive predisposition 10 | 1,442
Liver Cirrhosis, Experimental 10 | 769
chronic lymphosyte leukemia 10 | 204
non primary Sjogren syndrome sicca 10 | 891
Alzheimer's disease 9 | 658
Asthma 9 | 385
Intellectual disability 9 | 1,016
Lung Neoplasms 9 | 232
Lymphoma 9 | 81
Mantle cell lymphoma 9 | 23
Parkinson's disease 9 | 392
Seizures 9 | 596
breast carcinoma 9 | 1,638
pituitary cancer 9 | 1,972
Anemia 8 | 365
Cell Transformation, Neoplastic 8 | 97
Cholestasis, Extrahepatic 8 | 25
Dull intelligence 8 | 645
Frontal bossing 8 | 157
Hypoplastic mandible condyle 8 | 275
Low intelligence 8 | 645
Mandibular hypoplasia 8 | 275
Melanoma 8 | 711
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Micrognathism 8 | 275
Osteoporosis 8 | 363
Poor school performance 8 | 645
Short stature 8 | 531
Stomach Neoplasms 8 | 300
acute quadriplegic myopathy 8 | 1,158
esophageal adenocarcinoma 8 | 737
Brain Ischemia 7 | 110
Carcinoma, Hepatocellular 7 | 228
Hepatomegaly 7 | 285
Immunologic Deficiency Syndromes 7 | 113
Liver carcinoma 7 | 240
Neoplasm Metastasis 7 | 168
Neoplastic Cell Transformation 7 | 89
Orbital separation excessive 7 | 244
Renal Cell Carcinoma 7 | 214
Vascular disease 7 | 319
cystic fibrosis 7 | 1,696
hepatocellular carcinoma 7 | 547
pancreatic carcinoma 7 | 562
Attention deficit hyperactivity disorder 6 | 278
Chronic Lymphocytic Leukemia 6 | 262

Tissue

Blood and immune system 122 | 16,909
Digestive Tract 122 | 17,369
Endocrine System 122 | 18,159
Female tissues 121 | 17,400
Liver and Pancreas 121 | 16,750
Male tissues 121 | 17,142
Nervous System 121 | 16,725
Respiratory system 121 | 16,393
Skin and soft tissues 121 | 17,230
Urinary Tract 121 | 16,678
Cardiovascular System 120 | 15,192

Target Family

Non-IDG 97 | 12,091
Enzyme 52 | 4,145
Kinase 26 | 634
Transcription Factor 7 | 1,400

GO Process

Fc-epsilon receptor signaling ... 182 | 182
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
Ubiquitin-conjugating enzyme E2 variant 1 UBE2V1 Tbio Non-IDG -1.33153 18.0 188
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1-16 IGKV1-16 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1D-39 IGKV1D-39 Tdark Non-IDG 0.00000 0
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform PPP3CB Tbio Enzyme -1.53531 28.2 147
Immunoglobulin kappa variable 1-17 IGKV1-17 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1-39 IGKV1-39 Tdark Non-IDG 0.00000 0