Development Level

Tbio 14 | 11,445
Tclin 7 | 613
Tchem 6 | 1,598

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased fasted circulating g... 2 | 65
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
increased total body fat amoun... 2 | 134
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
cataract 1 | 92
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased large unstained cell... 1 | 11
decreased neutrophil cell numb... 1 | 42
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged uterus 1 | 11
fused cornea and lens 1 | 5
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
iris synechia 1 | 3
narrow eye opening 1 | 12
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
small superior vagus ganglion 1 | 74

Disease

Carcinoma 18 | 11,493
ovarian cancer 18 | 8,520
glioblastoma 14 | 5,792
medulloblastoma, large-cell 14 | 6,241
osteosarcoma 14 | 7,950
psoriasis 14 | 6,694
Cancer 13 | 2,499
lung cancer 13 | 4,740
Breast cancer 12 | 3,578
diabetes mellitus 10 | 1,728
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
primitive neuroectodermal tumor 10 | 3,035
invasive ductal carcinoma 9 | 2,951
pancreatic cancer 9 | 2,398
atypical teratoid / rhabdoid tumor 8 | 5,112
ependymoma 8 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
lung adenocarcinoma 8 | 2,716
lung carcinoma 8 | 2,843
Major Depressive Disorder 7 | 301
Schizophrenia 7 | 1,160
Vascular disease 7 | 319
adrenocortical carcinoma 7 | 1,428
malignant mesothelioma 7 | 3,232
Alzheimer's disease 6 | 658
Arthritis 6 | 290
Astrocytoma, Pilocytic 6 | 3,081
Bipolar Disorder 6 | 666
Kidney disease 6 | 430
Prostatic Neoplasms 6 | 495
Unipolar Depression 6 | 250
acute quadriplegic myopathy 6 | 1,158
astrocytic glioma 6 | 2,597
cystic fibrosis 6 | 1,696
esophageal adenocarcinoma 6 | 737
interstitial cystitis 6 | 2,312
juvenile dermatomyositis 6 | 1,187
oligodendroglioma 6 | 2,850
pituitary cancer 6 | 1,972
ulcerative colitis 6 | 1,819
Autosomal recessive predisposition 5 | 1,442
Breast Neoplasms 5 | 445
Heart disease 5 | 306
Hyperalgesia 5 | 83
Hypertension 5 | 396
Kidney cancer 5 | 2,613
Lung disease 5 | 142
Mammary Neoplasms 5 | 425
Neoplasm Invasiveness 5 | 161
Neoplasm Metastasis 5 | 168
Orbital separation excessive 5 | 244
Pick disease 5 | 1,894
Short stature 5 | 531
ductal carcinoma in situ 5 | 1,745
nasopharyngeal carcinoma 5 | 1,058
non-small cell lung cancer 5 | 2,890
primary pancreatic ductal adenocarcinoma 5 | 1,109
subependymal giant cell astrocytoma 5 | 2,287
Amyotrophic lateral sclerosis 4 | 451
Autistic Disorder 4 | 364
Big calvaria 4 | 147
Brain Ischemia 4 | 110
Cardiomyopathies 4 | 110
Cerebrovascular disease 4 | 238
Cleft Palate 4 | 271
Cognitive delay 4 | 608
Depressive disorder 4 | 409
Down syndrome 4 | 499
Duchenne muscular dystrophy 4 | 601
Dull intelligence 4 | 645
Endometriosis 4 | 540
Global developmental delay 4 | 608
Hypertensive disease 4 | 292
Increased head circumference 4 | 147
Increased size of cranium 4 | 147
Increased size of skull 4 | 147
Intellectual disability 4 | 1,016
Liver Cirrhosis, Experimental 4 | 769
Low intelligence 4 | 645
Lung Neoplasms 4 | 232
Mental Depression 4 | 333
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Multiple Sclerosis 4 | 540
Multiple myeloma 4 | 1,332
Obesity 4 | 678
Osteoporosis 4 | 363
Poor school performance 4 | 645
Pulmonary Fibrosis 4 | 106
Rheumatoid arthritis 4 | 1,191
adult high grade glioma 4 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
breast carcinoma 4 | 1,638
chronic rhinosinusitis 4 | 512
group 4 medulloblastoma 4 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
tuberculosis 4 | 2,010

Tissue

Blood and immune system 27 | 16,909
Endocrine System 27 | 18,159
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678
Digestive Tract 26 | 17,369
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Respiratory system 26 | 16,393
Cardiovascular System 25 | 15,192
Nervous System 24 | 16,725

Target Family

Non-IDG 12 | 12,091
Enzyme 5 | 4,145
Kinase 5 | 634
GPCR 3 | 408
Transcription Factor 2 | 1,400

GO Process

ERK1 and ERK2 cascade 27 | 27
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Sulfotransferase 1A3 SULT1A3 Tbio Enzyme -2.23459 201.6 133
mRNA decay activator protein ZFP36L1 ZFP36L1 Tbio Non-IDG -1.51339 38.6 285
Eotaxin CCL11 Tbio Non-IDG -2.99518 992.7 285
mRNA decay activator protein ZFP36L2 ZFP36L2 Tbio Non-IDG -1.54477 30.6 140
Pro-cathepsin H CTSH Tchem Enzyme -2.36930 222.0 253
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657
Prostaglandin E2 receptor EP4 subtype PTGER4 Tclin GPCR -2.97753 970.7 231
Metallothionein-3 MT3 Tbio Non-IDG -2.30937 197.7 87