Development Level

Tbio 22 | 11,445
Tchem 11 | 1,598
Tclin 5 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal pericardium morpholog... 1 | 26
abnormal snout morphology 1 | 23
abnormal urinary bladder morph... 1 | 11
decreased circulating glucose ... 1 | 126
decreased leukocyte cell numbe... 1 | 73
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
increased circulating glucose ... 1 | 24
increased grip strength 1 | 41
male infertility 1 | 123
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 26 | 11,493
ovarian cancer 25 | 8,520
Cancer 24 | 2,499
osteosarcoma 22 | 7,950
lung cancer 20 | 4,740
Breast cancer 19 | 3,578
glioblastoma 19 | 5,792
atypical teratoid / rhabdoid tumor 17 | 5,112
medulloblastoma, large-cell 17 | 6,241
psoriasis 17 | 6,694
pancreatic cancer 15 | 2,398
Kidney cancer 13 | 2,613
interstitial cystitis 13 | 2,312
Breast Neoplasms 12 | 445
Mammary Neoplasms 12 | 425
ependymoma 12 | 4,679
lung adenocarcinoma 12 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
Schizophrenia 9 | 1,160
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
invasive ductal carcinoma 9 | 2,951
ulcerative colitis 9 | 1,819
Autosomal recessive predisposition 8 | 1,442
Hypoplastic mandible condyle 8 | 275
Lung Neoplasms 8 | 232
Mandibular hypoplasia 8 | 275
Micrognathism 8 | 275
Rheumatoid arthritis 8 | 1,191
Stomach Neoplasms 8 | 300
diabetes mellitus 8 | 1,728
group 3 medulloblastoma 8 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
juvenile dermatomyositis 8 | 1,187
primary pancreatic ductal adenocarcinoma 8 | 1,109
Astrocytoma, Pilocytic 7 | 3,081
Multiple myeloma 7 | 1,332
Neoplasm Metastasis 7 | 168
Prostatic Neoplasms 7 | 495
ductal carcinoma in situ 7 | 1,745
group 4 medulloblastoma 7 | 1,855
malignant mesothelioma 7 | 3,232
oligodendroglioma 7 | 2,850
pituitary cancer 7 | 1,972
primitive neuroectodermal tumor 7 | 3,035
spina bifida 7 | 1,074
subependymal giant cell astrocytoma 7 | 2,287
Adenocarcinoma 6 | 122
Disease Progression 6 | 136
Noonan syndrome 6 | 34
Pick disease 6 | 1,894
adult high grade glioma 6 | 3,801
astrocytic glioma 6 | 2,597
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
cystic fibrosis 6 | 1,696
lung carcinoma 6 | 2,843
nasopharyngeal carcinoma 6 | 1,058
pancreatic carcinoma 6 | 562
tuberculosis 6 | 2,010
Adenocarcinoma of lung 5 | 142
Adenocarcinoma of lung (disorder) 5 | 60
Adenoma 5 | 167
Basal cell carcinoma 5 | 54
Byzanthine arch palate 5 | 194
Carcinoma, Hepatocellular 5 | 228
Colorectal Neoplasms 5 | 243
Delayed bone age 5 | 136
Diarrhea 5 | 253
Downward slant of palpebral fissure 5 | 158
Endometrial cancer 5 | 311
Endometriosis 5 | 540
Epilepsy 5 | 792
Frontal bossing 5 | 157
Gallbladder Neoplasms 5 | 10
Heart disease 5 | 306
Joint hyperflexibility 5 | 78
Liver carcinoma 5 | 240
Major Depressive Disorder 5 | 301
Melanoma 5 | 711
Muscle hypotonia 5 | 571
Neoplasm Invasiveness 5 | 161
Orbital separation excessive 5 | 244
Ovarian Neoplasms 5 | 102
Renal Cell Carcinoma 5 | 214
Seizures 5 | 596
Unipolar Depression 5 | 250
Upper respiratory tract disease 5 | 15
cutaneous lupus erythematosus 5 | 1,057
gallbladder neoplasm 5 | 10
hepatocellular carcinoma 5 | 547
non-small cell lung cancer 5 | 2,890
pediatric high grade glioma 5 | 1,064
Colonic Neoplasms 4 | 142
Concave bridge of nose 4 | 195
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Neuroblastoma 4 | 80
Pectus excavatum 4 | 100
Pediatric failure to thrive 4 | 365
Recurrence 4 | 33

Tissue

Blood and immune system 38 | 16,909
Digestive Tract 38 | 17,369
Endocrine System 38 | 18,159
Female tissues 38 | 17,400
Liver and Pancreas 38 | 16,750
Male tissues 38 | 17,142
Nervous System 38 | 16,725
Respiratory system 38 | 16,393
Skin and soft tissues 38 | 17,230
Urinary Tract 38 | 16,678
Cardiovascular System 36 | 15,192

Target Family

Non-IDG 21 | 12,091
Kinase 10 | 634
Enzyme 7 | 4,145

GO Process

ERBB2 signaling pathway 38 | 38
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein phosphatase non-receptor type 18 PTPN18 Tbio Enzyme -0.77241 5.46 77
Pro-neuregulin-4, membrane-bound isoform NRG4 Tbio Non-IDG -1.33564 24.6 137
Megakaryocyte-associated tyrosine-protein kinase MATK Tbio Kinase -2.98596 792.3 265
GRB2-associated-binding protein 1 GAB1 Tbio Non-IDG -1.55563 50.4 268
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Copine-3 CPNE3 Tbio Non-IDG -0.95488 10.4 119