Development Level

Tbio 25 | 10,625
Tchem 3 | 1,890
Tclin 2 | 602
Tdark 2 | 7,003

IMPC Phenotype

preweaning lethality, complete... 6 | 633
decreased caudal vertebrae num... 1 | 49
decreased circulating alanine ... 1 | 53
embryonic lethality prior to o... 1 | 148
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260

Disease

non-small cell lung cancer 23 | 2,798
lung cancer 22 | 4,473
ovarian cancer 21 | 8,491
medulloblastoma, large-cell 20 | 6,234
malignant mesothelioma 19 | 3,163
psoriasis 19 | 6,685
group 3 medulloblastoma 18 | 2,254
adrenocortical carcinoma 17 | 1,427
glioblastoma 15 | 5,572
osteosarcoma 15 | 7,933
primitive neuroectodermal tumor 15 | 3,031
Cancer 12 | 2,346
atypical teratoid / rhabdoid tumor 12 | 4,369
lung adenocarcinoma 12 | 2,714
pediatric high grade glioma 12 | 2,712
Breast cancer 11 | 3,098
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
invasive ductal carcinoma 9 | 2,950
colon cancer 8 | 1,475
ductal carcinoma in situ 8 | 1,745
nasopharyngeal carcinoma 8 | 1,056
Endometriosis 7 | 535
posterior fossa group A ependymoma 7 | 1,511
Meier-Gorlin syndrome 6 | 12
Atopic dermatitis 5 | 944
Seckel syndrome 5 | 35
EAR, PATELLA, SHORT STATURE SYNDROME 4 | 6
Waldenstrons macroglobulinemia 4 | 764
breast carcinoma 4 | 1,614
oligodendroglioma 4 | 2,849
sonic hedgehog group medulloblastoma 4 | 1,482
Microcephaly 3 | 149
Multiple myeloma 3 | 1,327
Pick disease 3 | 1,893
Rothmund-Thomson syndrome 3 | 22
adult high grade glioma 3 | 2,148
atypical teratoid/rhabdoid tumor 3 | 1,095
pilocytic astrocytoma 3 | 3,086
Acute lymphoid leukemia 2 | 25
Acute myeloid leukemia, disease 2 | 16
Acute promyelocytic leukemia, FAB M3 2 | 10
Adenocarcinoma of pancreas 2 | 12
Cervix endometriosis 2 | 3
DiGeorge syndrome 2 | 46
Lymphomatous meningitis 2 | 3
Malignant tumor of ovary 2 | 25
Meningeal Leukemia 2 | 7
Metastatic Breast Carcinoma 2 | 21
Polycystic Ovary Syndrome 2 | 334
Pulmonary emphysema 2 | 34
active Crohn's disease 2 | 918
astrocytoma 2 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
medulloblastoma 2 | 1,524
pancreatic cancer 2 | 2,300
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 788
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis and treatment for 6 months 2 | 686
ulcerative colitis 2 | 2,087
Adenoma 1 | 165
Age related macular degeneration 1 | 84
Alzheimer's disease 1 | 644
Azoospermia 1 | 89
Bladder Neoplasm 1 | 109
Bowen-Conradi syndrome 1 | 16
Colonic Neoplasms 1 | 126
Colorectal Neoplasms 1 | 217
Disease Progression 1 | 125
Familial adenomatous polyposis 1 | 33
Gaucher disease type 1 1 | 171
Glaucoma 1 | 135
Gout 1 | 93
Lactose intolerance 1 | 7
Liver carcinoma 1 | 217
Lynch syndrome 1 | 35
Malaria 1 | 140
Mammary Neoplasms 1 | 410
Menopause present (finding) 1 | 20
Nonsyndromic deafness 1 | 121
Peripheral Neuropathy 1 | 303
Poor school performance 1 | 13
Progressive multifocal leukoencephalopathy 1 | 24
Relapsing fever 1 | 16
Seborrheic keratosis 1 | 6
Seizure Adverse Event 1 | 19
Sertoli cell-only syndrome 1 | 36
Syphilis 1 | 18
Urinary bladder cancer 1 | 34
Velocardiofacial syndrome 1 | 45
glioblastoma multiforme 1 | 347
hepatocellular carcinoma 1 | 550
inflammatory breast cancer 1 | 404
ovarian neoplasm 1 | 97
pancreatic carcinoma 1 | 567
progressive supranuclear palsy 1 | 674
substance-related disorder 1 | 104
tuberculosis 1 | 1,563
tuberculosis and treatment for 3 months 1 | 327

Tissue

Blood and immune system 32 | 17,994
Cardiovascular System 32 | 17,957
Digestive Tract 32 | 18,472
Endocrine System 32 | 18,511
Female tissues 32 | 18,646
Liver and Pancreas 32 | 18,135
Male tissues 32 | 17,968
Nervous System 32 | 18,560
Respiratory system 32 | 17,483
Skin and soft tissues 32 | 18,114
Urinary Tract 32 | 18,443

Target Family

Non-IDG 24 | 11,969
Enzyme 7 | 4,146
Kinase 1 | 634

GO Process

DNA replication initiation 32 | 32
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Geminin coiled-coil domain-containing protein 1 GMNC Tdark Non-IDG -0.91558 8.83 48
Transcriptional activator protein Pur-alpha PURA Tbio Non-IDG -2.14001 153.6 155
Protein MCM10 homolog MCM10 Tbio Non-IDG -1.62619 49.9 70
Replication protein A 30 kDa subunit RPA4 Tbio Non-IDG -1.32394 20.7 110
DNA topoisomerase 2-binding protein 1 TOPBP1 Tbio Enzyme -2.01429 107.8 212
G1/S-specific cyclin-E1 CCNE1 Tchem Non-IDG -2.43326 239.2 741
Cell division control protein 45 homolog CDC45 Tbio Non-IDG -2.08011 105.8 227
DNA polymerase epsilon catalytic subunit A POLE Tclin Enzyme -2.17213 141.2 65
DNA replication licensing factor MCM2 MCM2 Tbio Non-IDG -2.39261 233.0 704
DNA primase large subunit PRIM2 Tbio Enzyme 0.00000 76