Development Level

Tbio 109 | 10,625
Tchem 21 | 1,890
Tclin 8 | 602
Tdark 6 | 7,003

IMPC Term

preweaning lethality, complete... 20 | 633
embryonic lethality prior to o... 6 | 148
preweaning lethality, incomple... 4 | 260
abnormal behavior 3 | 226
abnormal behavioral response t... 3 | 52
decreased lean body mass 3 | 195
embryonic lethality prior to t... 3 | 187
increased bone mineral density 3 | 52
abnormal maxilla morphology 2 | 16
abnormal placement of pupils 2 | 4
abnormal tooth morphology 2 | 24
decreased circulating glucose ... 2 | 121
decreased grip strength 2 | 123
decreased total body fat amoun... 2 | 186
increased blood urea nitrogen ... 2 | 44
increased bone mineral content 2 | 92
increased circulating sodium l... 2 | 71
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased lean body mass 2 | 107
increased mean corpuscular vol... 2 | 91
narrow eye opening 2 | 15
abnormal blood vessel morpholo... 1 | 2
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat/ hair morphology 1 | 18
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal iris morphology 1 | 12
abnormal locomotor activation 1 | 26
abnormal response to tactile s... 1 | 16
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
anophthalmia 1 | 20
cardiovascular system phenotyp... 1 | 35
corneal opacity 1 | 25
decreased T cell number 1 | 31
decreased basophil cell number 1 | 11
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating alanine ... 1 | 53
decreased circulating iron lev... 1 | 25
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased heart rate variabili... 1 | 11
decreased lumbar vertebrae num... 1 | 62
decreased rib number 1 | 59
hyperactivity 1 | 108
increased body weight 1 | 42
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating glucose ... 1 | 16
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased heart weight 1 | 37
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased thoracic vertebrae n... 1 | 8
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
thrombocytopenia 1 | 46
vertebral fusion 1 | 23

Disease

ovarian cancer 86 | 8,484
osteosarcoma 85 | 7,933
medulloblastoma, large-cell 66 | 6,234
psoriasis 63 | 6,685
lung cancer 62 | 4,466
malignant mesothelioma 62 | 3,162
group 3 medulloblastoma 61 | 2,254
glioblastoma 55 | 5,572
non-small cell lung cancer 55 | 2,798
Breast cancer 50 | 3,094
Cancer 49 | 2,346
primitive neuroectodermal tumor 47 | 3,031
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,289
adrenocortical carcinoma 38 | 1,427
lung adenocarcinoma 37 | 2,713
atypical teratoid / rhabdoid tumor 36 | 4,369
pediatric high grade glioma 36 | 2,712
colon cancer 35 | 1,475
invasive ductal carcinoma 35 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,988
nasopharyngeal carcinoma 29 | 1,056
ductal carcinoma in situ 28 | 1,745
atypical teratoid/rhabdoid tumor 26 | 1,095
oligodendroglioma 26 | 2,849
Carcinoma 23 | 2,147
posterior fossa group A ependymoma 21 | 1,511
breast carcinoma 19 | 1,614
ependymoma 19 | 2,514
Endometriosis 17 | 535
Waldenstrons macroglobulinemia 17 | 765
astrocytic glioma 16 | 2,241
astrocytoma 15 | 1,493
Multiple myeloma 14 | 1,327
Pick disease 14 | 1,893
Seckel syndrome 14 | 34
sonic hedgehog group medulloblastoma 14 | 1,482
Peripheral Neuropathy 13 | 303
Atopic dermatitis 12 | 944
adult high grade glioma 12 | 2,148
diabetes mellitus 12 | 1,663
pilocytic astrocytoma 12 | 3,086
pituitary cancer 12 | 1,972
subependymal giant cell astrocytoma 12 | 2,287
ulcerative colitis 12 | 2,087
Bloom syndrome 11 | 30
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
pancreatic cancer 11 | 2,300
Ataxia telangiectasia 10 | 31
Mammary Neoplasms 10 | 410
Nijmegen breakage syndrome 10 | 23
dermatomyositis 10 | 933
group 4 medulloblastoma 10 | 1,875
tuberculosis 10 | 1,557
Fanconi's anemia 9 | 50
Microcephaly 9 | 149
Werner syndrome 9 | 29
acute quadriplegic myopathy 9 | 1,157
interstitial cystitis 9 | 2,299
lung carcinoma 9 | 2,844
tuberculosis and treatment for 6 months 9 | 686
Alzheimer's disease 8 | 644
Meier-Gorlin syndrome 8 | 12
Neoplastic Syndromes, Hereditary 8 | 48
Prostatic Neoplasms 8 | 471
Rothmund-Thomson syndrome 8 | 22
juvenile dermatomyositis 8 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
IGA Glomerulonephritis 7 | 454
Malignant tumor of ovary 7 | 25
acute myeloid leukemia 7 | 780
esophageal adenocarcinoma 7 | 737
gastric cancer 7 | 430
inflammatory breast cancer 7 | 404
progressive supranuclear palsy 7 | 674
Hereditary Breast and Ovarian Cancer Syndrome 6 | 14
cutaneous lupus erythematosus 6 | 1,056
non primary Sjogren syndrome sicca 6 | 840
primary Sjogren syndrome 6 | 789
spina bifida 6 | 1,064
Acute lymphoid leukemia 5 | 25
Adenocarcinoma of pancreas 5 | 12
Colorectal Neoplasms 5 | 217
EAR, PATELLA, SHORT STATURE SYNDROME 5 | 6
Metastatic Breast Carcinoma 5 | 21
Neurodegenerative disease 5 | 383
gastric carcinoma 5 | 832
hepatocellular carcinoma 5 | 532
medulloblastoma 5 | 1,524
pancreatic carcinoma 5 | 567
Adenoid Cystic Carcinoma 4 | 99
Amyotrophic Lateral Sclerosis 4 | 431
Asthma 4 | 349
Cockayne syndrome 4 | 54
Intellectual disability 4 | 573
Liver carcinoma 4 | 217
Rheumatoid Arthritis 4 | 1,160
active Crohn's disease 4 | 918
aldosterone-producing adenoma 4 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
glioblastoma multiforme 4 | 347

Tissue

Male tissues 142 | 17,969
Blood and immune system 141 | 17,995
Digestive Tract 141 | 18,473
Endocrine System 141 | 18,512
Female tissues 141 | 18,647
Liver and Pancreas 141 | 18,136
Nervous System 141 | 18,561
Urinary Tract 141 | 18,444
Cardiovascular System 140 | 17,958
Respiratory system 140 | 17,484
Skin and soft tissues 140 | 18,115

Target Family

Non-IDG 79 | 11,971
Enzyme 46 | 4,146
Transcription Factor 8 | 1,400
Kinase 6 | 634
Epigenetic 4 | 242
TF/Epigenetic 1 | 38

GO Process

DNA replication 144 | 144
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Replication protein A 32 kDa subunit RPA2 Tbio Non-IDG -1.76828 59.7 468
Replication factor C subunit 3 RFC3 Tbio Non-IDG -1.28299 19.5 161
Replication factor C subunit 5 RFC5 Tbio Non-IDG -1.02728 11.1 64
Nuclear autoantigenic sperm protein NASP Tbio Non-IDG -1.72078 58.3 103
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.21148 186.3 172
Transcription factor E4F1 E4F1 Tbio Transcription Factor -1.47845 33.6 74
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 KCTD13 Tbio Non-IDG -0.85155 7.65 69
Replication factor C subunit 2 RFC2 Tbio Non-IDG -1.34287 19.7 194
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.59332 3912.4 208
Double-strand break repair protein MRE11A MRE11 Tbio Non-IDG -1.95631 90.0 412