Development Level

Tbio 49 | 11,651
Tdark 17 | 6,593
Tchem 5 | 1,388

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 3 | 278
small testis 2 | 58
abnormal coat-hair pigmentatio... 1 | 64
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
increased body weight 1 | 25
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
pale yolk sac 1 | 25
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 40 | 11,493
ovarian cancer 37 | 8,520
osteosarcoma 33 | 7,950
Cancer 24 | 2,499
lung cancer 24 | 4,740
psoriasis 24 | 6,694
group 3 medulloblastoma 22 | 4,104
medulloblastoma, large-cell 22 | 6,241
Breast cancer 19 | 3,578
atypical teratoid / rhabdoid tumor 19 | 5,112
malignant mesothelioma 19 | 3,232
glioblastoma 17 | 5,792
lung adenocarcinoma 14 | 2,716
ependymoma 13 | 4,679
primitive neuroectodermal tumor 12 | 3,035
Kidney cancer 10 | 2,613
Small head 10 | 374
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
invasive ductal carcinoma 10 | 2,951
non-small cell lung cancer 10 | 2,890
oligodendroglioma 10 | 2,850
Autosomal recessive predisposition 9 | 1,442
Intellectual disability 9 | 1,016
Short stature 9 | 531
Xeroderma pigmentosum 9 | 43
astrocytic glioma 9 | 2,597
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Mental and motor retardation 8 | 608
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
Breast Neoplasms 7 | 445
Mammary Neoplasms 7 | 425
Werner syndrome 7 | 29
adult high grade glioma 7 | 3,801
Ataxia telangiectasia 6 | 34
Cryptorchidism 6 | 296
Dull intelligence 6 | 645
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Nijmegen breakage syndrome 6 | 24
Poor school performance 6 | 645
Waldenstrons macroglobulinemia 6 | 765
colon cancer 6 | 1,478
group 4 medulloblastoma 6 | 1,855
Bloom syndrome 5 | 29
Chromosome Breakage 5 | 36
Decreased platelet count 5 | 111
Fetal Growth Retardation 5 | 189
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Multiple myeloma 5 | 1,332
Pick disease 5 | 1,894
Severe combined immunodeficiency 5 | 51
Thrombocytopenia 5 | 197
breast carcinoma 5 | 1,638
diabetes mellitus 5 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Adenocarcinoma of lung 4 | 142
Broad flat nasal bridge 4 | 236
Failure to gain weight 4 | 365
Fanconi anemia 4 | 56
Genetic Predisposition to Disease 4 | 27
Hereditary Breast and Ovarian Cancer Syndrome 4 | 14
Hypoplastic mandible condyle 4 | 275
Increased chromosomal breakage 4 | 27
Mandibular hypoplasia 4 | 275
Melanoma 4 | 711
Microcephaly 4 | 166
Micrognathism 4 | 275
Nasal bridge wide 4 | 236
Neurodegenerative disease 4 | 414
Pediatric failure to thrive 4 | 365
Rheumatoid arthritis 4 | 1,191
Seizures 4 | 596
acute myeloid leukemia 4 | 783
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
pancreatic cancer 4 | 2,398
tuberculosis 4 | 2,010
Abnormally small eyeball 3 | 97
Alzheimer's disease 3 | 658
Astrocytoma, Pilocytic 3 | 3,081
Atopic dermatitis 3 | 952
Cockayne syndrome 3 | 60
Decreased size of eyeball 3 | 97
Delayed bone age 3 | 136
Endometriosis 3 | 540
Epilepsy 3 | 792
Feeding difficulties in infancy 3 | 175
Short nose 3 | 132
Small nose 3 | 132
Stomach Neoplasms 3 | 300
adrenocortical carcinoma 3 | 1,428
cystic fibrosis 3 | 1,696
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 676

Tissue

Cardiovascular System 62 | 15,192
Digestive Tract 62 | 17,369
Endocrine System 62 | 18,159
Female tissues 61 | 17,400
Liver and Pancreas 61 | 16,750
Male tissues 61 | 17,142
Nervous System 61 | 16,725
Skin and soft tissues 61 | 17,230
Urinary Tract 61 | 16,678
Blood and immune system 60 | 16,909
Respiratory system 60 | 16,393

Target Family

Non-IDG 48 | 12,091
Enzyme 19 | 4,145
Transcription Factor 4 | 1,400

GO Process

DNA recombination 71 | 71
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meiosis-specific protein MEI4 MEI4 Tdark Non-IDG 0.00000 7
INO80 complex subunit B INO80B Tbio Non-IDG -1.16370 15.1 53
Ubiquitin carboxyl-terminal hydrolase isozyme L5 UCHL5 Tbio Enzyme -1.71687 51.9 225
Non-structural maintenance of chromosomes element 4 homolog A NSMCE4A Tdark Non-IDG 0.48 0.33 80
DNA repair protein RAD51 homolog 3 RAD51C Tbio Non-IDG -1.92798 88.3 269
X-ray repair cross-complementing protein 5 XRCC5 Tbio Non-IDG -2.68622 470.8 874
DNA repair protein XRCC4 XRCC4 Tbio Non-IDG -2.38352 232.9 322
RPA-interacting protein RPAIN Tbio Non-IDG -1.41218 24.1 153
Replication protein A 70 kDa DNA-binding subunit RPA1 Tchem Non-IDG -2.48277 297.9 350
DNA-(apurinic or apyrimidinic site) lyase APEX1 Tchem Enzyme -3.47746 2989.0 646