Development Level

Tbio 18 | 11,445
Tchem 5 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal eye morphology 2 | 68
decreased body length 2 | 101
preweaning lethality, incomple... 2 | 499
abnormal autopod morphology 1 | 1
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal joint morphology 1 | 23
abnormal limb bud morphology 1 | 17
abnormal maxilla morphology 1 | 17
abnormal motor capabilities-co... 1 | 5
abnormal nail morphology 1 | 8
abnormal placenta size 1 | 20
abnormal response to novel obj... 1 | 1
abnormal spine curvature 1 | 9
abnormal spleen morphology 1 | 55
abnormal stomach morphology 1 | 10
abnormal tail length 1 | 3
abnormal tail morphology 1 | 25
abnormal tibia morphology 1 | 14
brachydactyly 1 | 19
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
fusion of vertebral arches 1 | 7
hydrometra 1 | 53
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
small superior vagus ganglion 1 | 74
vertebral fusion 1 | 23

Disease

Carcinoma 15 | 11,493
osteosarcoma 12 | 7,950
ovarian cancer 12 | 8,520
psoriasis 11 | 6,694
Cancer 8 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
group 3 medulloblastoma 7 | 4,104
malignant mesothelioma 7 | 3,232
medulloblastoma, large-cell 7 | 6,241
Autosomal recessive predisposition 6 | 1,442
atypical teratoid / rhabdoid tumor 6 | 5,112
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung cancer 6 | 4,740
glioblastoma 5 | 5,792
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
primitive neuroectodermal tumor 5 | 3,035
Astrocytoma, Pilocytic 4 | 3,081
Atopic dermatitis 4 | 952
Breast cancer 4 | 3,578
Kidney cancer 4 | 2,613
adrenocortical carcinoma 4 | 1,428
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
ulcerative colitis 4 | 1,819
Adenocarcinoma of lung 3 | 142
Bloom syndrome 3 | 29
Endometriosis 3 | 540
Proteinuria 3 | 144
Waldenstrons macroglobulinemia 3 | 765
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Abdominal Pain 2 | 98
Adult onset 2 | 82
Arthritis 2 | 290
Brain disease 2 | 96
Chronic Lymphocytic Leukemia 2 | 262
Colorectal Neoplasms 2 | 243
Connective tissue disease 2 | 62
Decreased platelet count 2 | 111
Dementia 2 | 175
Disease Models, Animal 2 | 155
Dysarthria 2 | 192
Dyspnea 2 | 76
Elevated hepatic transaminases 2 | 81
Epilepsy 2 | 792
Fever 2 | 138
Heart disease 2 | 306
Hematuria 2 | 36
Hepatic enzyme increased 2 | 81
Intermittent migraine headaches 2 | 68
Kidney Failure 2 | 111
Kidney disease 2 | 430
Leukoencephalopathies 2 | 29
Liver Cirrhosis, Experimental 2 | 769
Liver Dysfunction 2 | 99
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Lupus Erythematosus, Systemic 2 | 67
Lupus erythematosus 2 | 57
Migraine Disorders 2 | 76
Neurodegenerative disease 2 | 414
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Nijmegen breakage syndrome 2 | 24
Progressive disorder 2 | 142
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Renal glomerular disease 2 | 12
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Skeletal muscle atrophy 2 | 139
Skin Ulcer 2 | 48
Subclinical abnormal liver function tests 2 | 81
Systemic lupus erythematosus 2 | 194
Thrombocytopenia 2 | 197
Transaminases increased 2 | 81
Vascular disease 2 | 319
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
medulloblastoma 2 | 720
muscle degeneration 2 | 139
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung carcinoma 2 | 317
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 24 | 16,909
Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Cardiovascular System 21 | 15,192

Target Family

Enzyme 16 | 4,145
Non-IDG 6 | 12,091
GPCR 1 | 408
Kinase 1 | 634

GO Process

DNA metabolic process 24 | 24
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-dependent DNA helicase Q5 RECQL5 Tbio Enzyme -1.67373 56.2 148
Alpha-1D adrenergic receptor ADRA1D Tclin GPCR -2.25789 174.5 120
ERI1 exoribonuclease 3 ERI3 Tbio Enzyme -0.80731 5.34 67
Deoxyribonuclease gamma DNASE1L3 Tbio Enzyme -2.31583 207.3 157
3'-5' exoribonuclease 1 ERI1 Tbio Enzyme -1.96395 87.8 172
Proliferation marker protein Ki-67 MKI67 Tbio Non-IDG -2.50106 270.3 1434
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 SMARCAL1 Tbio Non-IDG -1.74852 65.1 133
Unconventional myosin-XVIIIa MYO18A Tbio Non-IDG -1.15048 14.2 35
DNA polymerase subunit gamma-1 POLG Tchem Enzyme -2.63005 414.1 128
DNA topoisomerase 2-binding protein 1 TOPBP1 Tbio Enzyme -2.04312 118.0 230