Development Level

Tbio 11 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

abnormal embryo size 2 | 220
abnormal behavior 1 | 298
abnormal eye morphology 1 | 68
abnormal vertebrae morphology 1 | 18
decreased body weight 1 | 161
decreased circulating glycerol... 1 | 16
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating triglyce... 1 | 42
increased startle reflex 1 | 112
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
tremors 1 | 39

Disease

Carcinoma 12 | 11,493
ovarian cancer 11 | 8,520
lung cancer 10 | 4,740
osteosarcoma 10 | 7,950
medulloblastoma, large-cell 9 | 6,241
Cancer 8 | 2,499
group 3 medulloblastoma 8 | 4,104
Autosomal recessive predisposition 7 | 1,442
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 7 | 5,792
malignant mesothelioma 7 | 3,232
Ataxia telangiectasia 6 | 34
Breast cancer 6 | 3,578
Short stature 6 | 531
ependymoma 6 | 4,679
psoriasis 6 | 6,694
Hereditary Breast and Ovarian Cancer Syndrome 5 | 14
Kidney cancer 5 | 2,613
Nijmegen breakage syndrome 5 | 24
Pick disease 5 | 1,894
Small head 5 | 374
adult high grade glioma 5 | 3,801
colon cancer 5 | 1,478
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
Chromosome Breakage 4 | 36
Dull intelligence 4 | 645
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Microcephaly 4 | 166
Poor school performance 4 | 645
astrocytic glioma 4 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pituitary cancer 4 | 1,972
Astrocytoma, Pilocytic 3 | 3,081
Birthmark 3 | 35
Breast Neoplasms 3 | 445
Bronchiectasis 3 | 64
Cafe-au-Lait Spots 3 | 37
Convex nasal ridge 3 | 37
Fanconi anemia 3 | 56
Fetal Growth Retardation 3 | 189
Hyperplasia of nose 3 | 23
Hypertrophy of nose 3 | 23
Hypoplastic mandible condyle 3 | 275
Increased chromosomal breakage 3 | 27
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Large nose 3 | 23
Liver cancer 3 | 604
Mammary Neoplasms 3 | 425
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Paranasal Sinus Diseases 3 | 34
Prostatic Neoplasms 3 | 495
Seckel syndrome 3 | 34
Sinusitis 3 | 65
Werner syndrome 3 | 29
ductal carcinoma in situ 3 | 1,745
invasive ductal carcinoma 3 | 2,951
nasopharyngeal carcinoma 3 | 1,058
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
subependymal giant cell astrocytoma 3 | 2,287
Adenoid Cystic Carcinoma 2 | 99
Bilateral fifth finger clinodactyly 2 | 110
Cachexia 2 | 50
Carcinoma, Adenoid Cystic 2 | 99
Curvature of little finger 2 | 110
Delayed bone age 2 | 136
Diarrhea 2 | 253
Dysarthria 2 | 192
Dystonia 2 | 164
Dystonic disease 2 | 106
Gait abnormality 2 | 135
Immunoglobulin A deficiency (disorder) 2 | 19
Leukemia 2 | 104
Lymphoma 2 | 81
Multiple Sclerosis 2 | 540
Muscle Spasticity 2 | 195
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Polycystic ovary syndrome 2 | 360
Prostate cancer 2 | 175
Recurrent respiratory infections 2 | 141
Retrognathia 2 | 54
Schizophrenia 2 | 1,160
Squamous cell carcinoma 2 | 129
Telangiectasis 2 | 36
Waldenstrons macroglobulinemia 2 | 765
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
inflammatory breast cancer 2 | 286
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
progressive supranuclear palsy 2 | 676
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Non-IDG 9 | 12,091
Enzyme 3 | 4,145
Epigenetic 2 | 242
Kinase 1 | 634

GO Process

DNA double-strand break proces... 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA endonuclease RBBP8 RBBP8 Tbio Enzyme -2.17933 148.4 308
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 SMARCAD1 Tbio Non-IDG -1.16844 16.4 95
Breast cancer type 1 susceptibility protein BRCA1 Tchem Non-IDG -3.76784 6081.3 1542
BRCA1-associated RING domain protein 1 BARD1 Tbio Non-IDG -2.09264 120.7 236
Exonuclease 3'-5' domain-containing protein 2 EXD2 Tbio Enzyme -0.97829 7.74 51
Ubiquitin-conjugating enzyme E2 N UBE2N Tbio Non-IDG -2.08846 107.8 268
Double-strand break repair protein MRE11 MRE11 Tbio Non-IDG -2.02762 98.5 459
Histone-lysine N-methyltransferase SETMAR SETMAR Tbio Epigenetic -1.33346 26.5 119
DNA replication ATP-dependent helicase/nuclease DNA2 DNA2 Tbio Enzyme -2.42159 256.1 101
Nibrin NBN Tbio Non-IDG -1.95649 97.2 1094