Development Level

Tbio 43 | 11,445
Tchem 19 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased caudal vertebrae num... 2 | 53
decreased lean body mass 2 | 135
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal external female genit... 1 | 1
abnormal external male genital... 1 | 1
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal limb bud morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal placenta morphology 1 | 5
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
decreased anxiety-related resp... 1 | 12
decreased body weight 1 | 161
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
hemorrhage 1 | 23
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
sclerocornea 1 | 2
small seminal vesicle 1 | 10
small testis 1 | 58
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

ovarian cancer 44 | 8,520
osteosarcoma 38 | 7,950
psoriasis 36 | 6,694
Carcinoma 35 | 11,493
medulloblastoma, large-cell 35 | 6,241
glioblastoma 33 | 5,792
lung cancer 33 | 4,740
group 3 medulloblastoma 32 | 4,104
Cancer 31 | 2,499
atypical teratoid / rhabdoid tumor 28 | 5,112
malignant mesothelioma 26 | 3,232
Breast cancer 23 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
primitive neuroectodermal tumor 21 | 3,035
ependymoma 20 | 4,679
pancreatic cancer 20 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
non-small cell lung cancer 19 | 2,890
adult high grade glioma 17 | 3,801
lung adenocarcinoma 16 | 2,716
ductal carcinoma in situ 15 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
adrenocortical carcinoma 13 | 1,428
oligodendroglioma 13 | 2,850
colon cancer 12 | 1,478
invasive ductal carcinoma 12 | 2,951
Kidney cancer 11 | 2,613
Breast Neoplasms 10 | 445
Endometriosis 10 | 540
Mammary Neoplasms 10 | 425
Prostatic Neoplasms 10 | 495
Stomach Neoplasms 10 | 300
astrocytic glioma 10 | 2,597
breast carcinoma 10 | 1,638
ulcerative colitis 10 | 1,819
Waldenstrons macroglobulinemia 9 | 765
acute quadriplegic myopathy 9 | 1,158
juvenile dermatomyositis 9 | 1,187
tuberculosis 9 | 2,010
Atopic dermatitis 8 | 952
dermatomyositis 8 | 966
diabetes mellitus 8 | 1,728
pituitary cancer 8 | 1,972
Chronic Lymphocytic Leukemia 7 | 262
Melanoma 7 | 711
astrocytoma 7 | 1,146
nasopharyngeal carcinoma 7 | 1,058
primary pancreatic ductal adenocarcinoma 7 | 1,109
Astrocytoma, Pilocytic 6 | 3,081
Carcinoma, Hepatocellular 6 | 228
Colonic Neoplasms 6 | 142
Liver carcinoma 6 | 240
Multiple myeloma 6 | 1,332
Pick disease 6 | 1,894
Renal Cell Carcinoma 6 | 214
Rheumatoid arthritis 6 | 1,191
esophageal adenocarcinoma 6 | 737
gastric cancer 6 | 459
interstitial cystitis 6 | 2,312
lung carcinoma 6 | 2,843
pancreatic carcinoma 6 | 562
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
spina bifida 6 | 1,074
subependymal giant cell astrocytoma 6 | 2,287
Amyotrophic lateral sclerosis 5 | 451
Anemia 5 | 365
Ataxia telangiectasia 5 | 34
Duchenne muscular dystrophy 5 | 601
Intellectual disability 5 | 1,016
Liver cancer 5 | 604
Lung Neoplasms 5 | 232
Pancreatic Neoplasm 5 | 85
Polycystic ovary syndrome 5 | 360
Schizophrenia 5 | 1,160
acute myeloid leukemia 5 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
group 4 medulloblastoma 5 | 1,855
hepatocellular carcinoma 5 | 547
pediatric high grade glioma 5 | 1,064
primary Sjogren syndrome 5 | 735
Adenoid Cystic Carcinoma 4 | 99
Adenoma 4 | 167
Autosomal recessive predisposition 4 | 1,442
Bladder Neoplasm 4 | 112
Carcinoma, Adenoid Cystic 4 | 99
Colorectal Neoplasms 4 | 243
Epilepsy 4 | 792
HIV Infections 4 | 102
Leukemia, Lymphocytic, Chronic, B-Cell 4 | 34
Liver Cirrhosis, Experimental 4 | 769
Lymphoma 4 | 81
Male infertility 4 | 206
Mesothelioma, Malignant 4 | 105
Neurodegenerative disease 4 | 414
Seizures 4 | 596
Short stature 4 | 531
Squamous cell carcinoma of esophagus 4 | 77
Urinary Bladder Neoplasms 4 | 114
gastric carcinoma 4 | 807
progressive supranuclear palsy 4 | 676

Tissue

Blood and immune system 63 | 16,909
Digestive Tract 63 | 17,369
Endocrine System 63 | 18,159
Respiratory system 63 | 16,393
Female tissues 62 | 17,400
Liver and Pancreas 62 | 16,750
Male tissues 62 | 17,142
Nervous System 62 | 16,725
Skin and soft tissues 62 | 17,230
Urinary Tract 62 | 16,678
Cardiovascular System 61 | 15,192

Target Family

Non-IDG 36 | 12,091
Transcription Factor 10 | 1,400
Enzyme 8 | 4,145
Kinase 7 | 634
Epigenetic 3 | 242

GO Process

DNA damage response, signal tr... 64 | 64
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-arginine methyltransferase CARM1 CARM1 Tchem Epigenetic -2.04034 130.8 476
CCR4-NOT transcription complex subunit 1 CNOT1 Tbio Non-IDG -2.10799 119.0 37
Death domain-containing protein CRADD CRADD Tbio Non-IDG -1.34614 23.0 400
Zinc finger protein 385A ZNF385A Tbio Non-IDG -0.03141 1.24 99
Caspase-2 CASP2 Tchem Enzyme -2.62373 431.8 571
Protein BTG2 BTG2 Tbio Non-IDG -2.10376 142.7 209
Centromere protein J CENPJ Tbio Non-IDG -1.79588 59.0 102
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
CCR4-NOT transcription complex subunit 2 CNOT2 Tbio Non-IDG -2.83887 627.5 303