Development Level

Tbio 4 | 11,445

IMPC Phenotype

abnormal heart morphology 1 | 162
decreased circulating insulin ... 1 | 76
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979

Disease

group 3 medulloblastoma 4 | 4,104
osteosarcoma 4 | 7,950
ovarian cancer 3 | 8,520
Carcinoma 2 | 11,493
malignant mesothelioma 2 | 3,232
Absent speech 1 | 43
Acute stress disorder 1 | 6
Atrophy of cerebellum 1 | 103
Atrophy of tongue 1 | 4
Autosomal recessive predisposition 1 | 1,442
Axial hypotonia 1 | 46
Brachydactyly 1 | 156
Breast cancer 1 | 3,578
Calcinosis 1 | 70
Cardiac arrest 1 | 36
Cerebellar cyst 1 | 5
Cerebellar degeneration 1 | 103
Cerebral atrophy 1 | 178
Cognitive delay 1 | 608
Contracture 1 | 96
Contracture of joint 1 | 93
Defective or absent horizontal voluntary eye movements 1 | 25
Degenerative brain disorder 1 | 100
Dyskinesia of esophagus 1 | 10
Fasciculation, Tongue 1 | 8
Feeding difficulties 1 | 127
Flexion contracture 1 | 93
Flexion contractures of joints 1 | 93
Foot Deformities 1 | 30
Global developmental delay 1 | 608
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Highly variable severity 1 | 157
Hyperreflexia 1 | 209
Infratentorial atrophy 1 | 103
Kidney cancer 1 | 2,613
Liver neoplasms 1 | 130
Mental and motor retardation 1 | 608
Microvillus inclusion disease 1 | 8
Mixed connective tissue disease 1 | 16
Multiple myeloma 1 | 1,332
Muscle Spasticity 1 | 195
Myositis 1 | 30
Neurodegenerative disease 1 | 414
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Nystagmus 1 | 317
Oculomotor apraxia 1 | 25
PONTOCEREBELLAR HYPOPLASIA, TYPE 1B 1 | 1
Perlman syndrome 1 | 9
Polyhydramnios 1 | 108
Pontocerebellar Hypoplasia Type 1 1 | 5
Pontocerebellar hypoplasia 1 | 36
Poor growth 1 | 114
Poor head control 1 | 14
Precancerous Conditions 1 | 80
Prenatal onset 1 | 139
Progressive microcephaly 1 | 32
Respiratory Insufficiency 1 | 132
Respiratory function loss 1 | 121
Rheumatoid arthritis 1 | 1,191
Skeletal muscle atrophy 1 | 139
Strabismus 1 | 270
Supratentorial atrophy 1 | 94
Systemic lupus erythematosus 1 | 194
Systemic scleroderma 1 | 60
Telangiectasis 1 | 36
Variable expressivity 1 | 157
Very poor growth 1 | 114
Wasting of tongue 1 | 4
astrocytic glioma 1 | 2,597
colon cancer 1 | 1,478
hepatocellular carcinoma 1 | 547
interstitial lung disease 1 | 298
invasive ductal carcinoma 1 | 2,951
lung cancer 1 | 4,740
muscle degeneration 1 | 139
non-small cell lung cancer 1 | 2,890
nonverbal 1 | 43
oligodendroglioma 1 | 2,850
pancreatic cancer 1 | 2,398
pancreatic carcinoma 1 | 562
tuberculosis 1 | 2,010

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 3 | 12,091
Enzyme 1 | 4,145

GO Process

CUT catabolic process 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Exosome component 10 EXOSC10 Tbio Non-IDG -2.45249 279.1 123
Exosome complex exonuclease RRP44 DIS3 Tbio Enzyme -1.80730 64.2 141
Exosome complex component RRP4 EXOSC2 Tbio Non-IDG -0.28065 2.13 121
Exosome complex component RRP40 EXOSC3 Tbio Non-IDG -1.19555 14.9 179