Development Level

Tbio 44 | 10,625
Tdark 10 | 7,003
Tchem 6 | 1,890
Tclin 1 | 602

IMPC Term

preweaning lethality, complete... 6 | 633
decreased circulating HDL chol... 4 | 77
decreased circulating LDL chol... 3 | 37
decreased circulating choleste... 3 | 85
embryonic lethality prior to t... 3 | 187
decreased body weight 2 | 174
decreased caudal vertebrae num... 2 | 49
decreased circulating free fat... 2 | 39
decreased rib number 2 | 59
decreased total body fat amoun... 2 | 186
embryonic lethality prior to o... 2 | 148
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal retinal pigmentation 1 | 61
abnormal sacral vertebrae morp... 1 | 5
abnormal skin condition 1 | 6
abnormal testis morphology 1 | 30
absent vibrissae 1 | 14
decreased CD11b-low dendritic ... 1 | 3
decreased KLRG1-positive NK ce... 1 | 9
decreased NK cell number 1 | 16
decreased blood urea nitrogen ... 1 | 31
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased lumbar vertebrae num... 1 | 62
decreased startle reflex 1 | 48
enlarged heart 1 | 111
enlarged heart atrium 1 | 2
hydrometra 1 | 13
increased CD11b-high dendritic... 1 | 5
increased blood urea nitrogen ... 1 | 44
increased circulating free fat... 1 | 17
increased fasted circulating g... 1 | 68
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased sacral vertebrae num... 1 | 62
small testis 1 | 37

Disease

ovarian cancer 40 | 8,484
osteosarcoma 34 | 7,933
glioblastoma 24 | 5,572
medulloblastoma, large-cell 23 | 6,234
atypical teratoid / rhabdoid tumor 20 | 4,369
psoriasis 17 | 6,685
lung cancer 16 | 4,466
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,289
invasive ductal carcinoma 13 | 2,950
pancreatic cancer 13 | 2,300
Multiple myeloma 12 | 1,327
malignant mesothelioma 12 | 3,162
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
Rheumatoid Arthritis 11 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
lung adenocarcinoma 11 | 2,713
lung carcinoma 11 | 2,844
Cancer 10 | 2,346
ependymoma 10 | 2,514
non-small cell lung cancer 10 | 2,798
pediatric high grade glioma 10 | 2,712
pilocytic astrocytoma 10 | 3,086
ulcerative colitis 10 | 2,087
Breast cancer 9 | 3,094
Carcinoma 9 | 2,147
interstitial cystitis 9 | 2,299
primitive neuroectodermal tumor 9 | 3,031
acute quadriplegic myopathy 8 | 1,157
astrocytic glioma 8 | 2,241
breast carcinoma 8 | 1,614
cutaneous lupus erythematosus 8 | 1,056
pancreatic carcinoma 8 | 567
tuberculosis 8 | 1,557
group 4 medulloblastoma 7 | 1,875
medulloblastoma 7 | 1,524
oligodendroglioma 7 | 2,849
spina bifida 7 | 1,064
Pick disease 6 | 1,893
astrocytoma 6 | 1,493
cystic fibrosis 6 | 1,665
non primary Sjogren syndrome sicca 6 | 840
posterior fossa group A ependymoma 6 | 1,511
Vascular disease 5 | 281
active Crohn's disease 5 | 918
gastric carcinoma 5 | 832
pituitary cancer 5 | 1,972
sonic hedgehog group medulloblastoma 5 | 1,482
tuberculosis and treatment for 6 months 5 | 686
Congenital dyserythropoietic anemia 4 | 17
Endometriosis 4 | 535
IGA Glomerulonephritis 4 | 454
Myocardial Ischemia 4 | 169
Stomach Neoplasms 4 | 282
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 780
adult high grade glioma 4 | 2,148
aldosterone-producing adenoma 4 | 664
dermatomyositis 4 | 933
diabetes mellitus 4 | 1,663
esophageal adenocarcinoma 4 | 737
gastric cancer 4 | 430
hepatocellular carcinoma 4 | 532
hereditary spastic paraplegia 4 | 313
juvenile dermatomyositis 4 | 1,189
mucosa-associated lymphoid tissue lymphoma 4 | 480
primary Sjogren syndrome 4 | 789
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis and treatment for 3 months 4 | 327
Chylomicron retention disease 3 | 11
Duchenne muscular dystrophy 3 | 602
Epilepsy 3 | 346
Factor VIII deficiency 3 | 10
Intellectual disability 3 | 573
Parkinson's disease 3 | 364
Schizophrenia 3 | 501
Tetanus 3 | 66
atypical teratoid/rhabdoid tumor 3 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,475
inflammatory breast cancer 3 | 404
nephrosclerosis 3 | 329
non-small cell lung carcinoma 3 | 413
posterior fossa group B ependymoma 3 | 1,530
Amyotrophic Lateral Sclerosis 2 | 431
Bipolar Disorder 2 | 266
Chronic Lymphocytic Leukemia 2 | 242
Chronic obstructive pulmonary disease 2 | 146
Down syndrome 2 | 548
Heart disease 2 | 279
Hypersensitivity reaction type II disease 2 | 235
Liver carcinoma 2 | 217
Microcephaly 2 | 149
Neurodegenerative disease 2 | 383
Prostatic Neoplasms 2 | 471
Pulmonary Embolism 2 | 45
Warburg micro syndrome 2 | 19
fibroadenoma 2 | 557
head and neck cancer 2 | 270

Tissue

Blood and immune system 61 | 17,995
Cardiovascular System 61 | 17,958
Digestive Tract 61 | 18,473
Endocrine System 61 | 18,512
Female tissues 61 | 18,647
Liver and Pancreas 61 | 18,136
Male tissues 61 | 17,969
Nervous System 61 | 18,561
Respiratory system 61 | 17,484
Urinary Tract 61 | 18,444
Skin and soft tissues 60 | 18,115

Target Family

Non-IDG 48 | 11,971
Enzyme 10 | 4,146
Ion Channel 1 | 341
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

COPII vesicle coating 61 | 61
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A ANKRD28 Tbio Enzyme -0.56847 4.64 67
Golgin subfamily A member 2 GOLGA2 Tbio Non-IDG -1.94177 80.5 168
Trafficking protein particle complex subunit 10 TRAPPC10 Tbio Non-IDG -1.31760 17.2 89
Multiple coagulation factor deficiency protein 2 MCFD2 Tbio Non-IDG -1.48823 32.9 126
CD59 glycoprotein CD59 Tbio Non-IDG -3.23780 1768.6 739
Ras-related protein Rab-1B RAB1B Tbio Enzyme 36.3 104
Ras-related protein Rab-1A RAB1A Tbio Enzyme -2.35747 242.5 102
Coagulation factor V F5 Tbio Non-IDG -2.71038 504.1 162
Protein transport protein Sec16A SEC16A Tbio Non-IDG -1.43274 30.3 30
Kelch-like protein 12 KLHL12 Tbio Non-IDG -0.95785 9.67 180