Development Level

Tbio 49 | 11,178
Tdark 7 | 6,569
Tchem 6 | 1,885
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 8 | 979
decreased circulating HDL chol... 3 | 68
decreased circulating LDL chol... 3 | 38
decreased circulating choleste... 3 | 93
embryonic lethality prior to t... 3 | 278
abnormal kidney morphology 2 | 65
decreased circulating free fat... 2 | 31
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
small testis 2 | 58
abnormal allantois morphology 1 | 8
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal left-right axis patte... 1 | 2
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal somite shape 1 | 5
abnormal stomach morphology 1 | 10
abnormal tail bud morphology 1 | 8
abnormal testis morphology 1 | 43
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
brachydactyly 1 | 19
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged seminal vesicle 1 | 10
hydroencephaly 1 | 14
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased circulating free fat... 1 | 20
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
syndactyly 1 | 23

Disease

ovarian cancer 42 | 8,297
Carcinoma 36 | 11,192
osteosarcoma 34 | 7,766
glioblastoma 24 | 5,635
medulloblastoma, large-cell 23 | 6,086
atypical teratoid / rhabdoid tumor 20 | 4,971
psoriasis 17 | 6,514
lung cancer 16 | 4,607
Kidney cancer 15 | 2,548
ependymoma 15 | 4,559
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,204
tuberculosis 15 | 1,963
invasive ductal carcinoma 13 | 2,867
pancreatic cancer 13 | 2,322
Autosomal recessive predisposition 12 | 1,407
Multiple myeloma 12 | 1,296
adult high grade glioma 12 | 3,701
malignant mesothelioma 12 | 3,135
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,911
Breast cancer 11 | 3,469
Cancer 11 | 2,388
Rheumatoid arthritis 11 | 1,156
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,902
lung adenocarcinoma 11 | 2,627
lung carcinoma 11 | 2,755
non-small cell lung cancer 11 | 2,799
Astrocytoma, Pilocytic 10 | 3,006
group 4 medulloblastoma 9 | 1,806
interstitial cystitis 9 | 2,237
primitive neuroectodermal tumor 9 | 2,957
ulcerative colitis 9 | 1,765
acute quadriplegic myopathy 8 | 1,133
astrocytic glioma 8 | 2,530
breast carcinoma 8 | 1,589
cutaneous lupus erythematosus 8 | 1,016
pancreatic carcinoma 8 | 555
spina bifida 8 | 1,053
Pick disease 7 | 1,856
non primary Sjogren syndrome sicca 7 | 861
oligodendroglioma 7 | 2,768
astrocytoma 6 | 1,113
cystic fibrosis 6 | 1,629
Melanoma 5 | 689
Vascular disease 5 | 294
active Crohn's disease 5 | 882
gastric carcinoma 5 | 781
group 3 medulloblastoma 5 | 4,002
hepatocellular carcinoma 5 | 536
pituitary cancer 5 | 1,915
Bipolar Disorder 4 | 646
Congenital dyserythropoietic anemia 4 | 18
Endometriosis 4 | 521
Intellectual disability 4 | 998
Myocardial Ischemia 4 | 162
Schizophrenia 4 | 1,136
Stomach Neoplasms 4 | 287
Waldenstrons macroglobulinemia 4 | 742
acute myeloid leukemia 4 | 760
aldosterone-producing adenoma 4 | 646
dermatomyositis 4 | 941
diabetes mellitus 4 | 1,683
esophageal adenocarcinoma 4 | 696
gastric cancer 4 | 445
hereditary spastic paraplegia 4 | 313
juvenile dermatomyositis 4 | 1,147
medulloblastoma 4 | 702
mucosa-associated lymphoid tissue lymphoma 4 | 473
posterior fossa group A ependymoma 4 | 456
primary Sjogren syndrome 4 | 710
subependymal giant cell astrocytoma 4 | 2,230
Acquired scoliosis 3 | 274
Amyotrophic lateral sclerosis 3 | 437
Chylomicron retention disease 3 | 11
Curvature of spine 3 | 275
Dental caries 3 | 157
Dermatologic disorders 3 | 88
Duchenne muscular dystrophy 3 | 587
Elevated hepatic transaminases 3 | 79
Epilepsy 3 | 775
Hepatic enzyme increased 3 | 79
Liver Dysfunction 3 | 97
Liver enzymes abnormal 3 | 79
Liver function test increased 3 | 79
Liver function tests abnormal finding 3 | 79
Major Depressive Disorder 3 | 293
Muscle hypotonia 3 | 562
Parkinson's disease 3 | 378
Pulmonary Fibrosis 3 | 101
Rotting teeth 3 | 69
Short stature 3 | 514
Skin cancer 3 | 451
Subclinical abnormal liver function tests 3 | 79
Transaminases increased 3 | 79
atypical teratoid/rhabdoid tumor 3 | 349
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 492
chronic rhinosinusitis 3 | 505
colon cancer 3 | 1,428
nephrosclerosis 3 | 314
sonic hedgehog group medulloblastoma 3 | 459

Tissue

Digestive Tract 63 | 17,369
Endocrine System 63 | 18,159
Female tissues 63 | 17,400
Male tissues 63 | 17,142
Nervous System 63 | 16,725
Respiratory system 63 | 16,393
Skin and soft tissues 63 | 17,230
Blood and immune system 62 | 16,909
Cardiovascular System 62 | 15,192
Liver and Pancreas 62 | 16,750
Urinary Tract 62 | 16,678

Target Family

Non-IDG 50 | 12,091
Enzyme 10 | 4,145
Ion Channel 1 | 344
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

COPII vesicle coating 63 | 63
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cathepsin Z CTSZ Tchem Enzyme -1.80363 70.2 233
Serine/threonine-protein phosphatase 6 catalytic subunit PPP6C Tbio Enzyme -2.41091 208.5 230
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.27566 1855.5 168
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91664 86.4 148
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Trafficking protein particle complex subunit 9 TRAPPC9 Tbio Non-IDG -2.18750 147.6 86
Trafficking protein particle complex subunit 4 TRAPPC4 Tbio Non-IDG -0.87026 9.19 204
Trafficking protein particle complex subunit 6B TRAPPC6B Tdark Non-IDG -0.52288 3.07 35
General vesicular transport factor p115 USO1 Tbio Non-IDG -2.10663 123.7 247
Sec1 family domain-containing protein 1 SCFD1 Tbio Non-IDG -1.50460 33.8 170