Development Level

Tbio 27 | 11,651
Tdark 2 | 6,593

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal embryo size 1 | 220
abnormal maxilla morphology 1 | 17
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
decreased body weight 1 | 161
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16

Disease

group 3 medulloblastoma 21 | 4,104
glioblastoma 19 | 5,792
medulloblastoma, large-cell 19 | 6,241
psoriasis 19 | 6,694
atypical teratoid / rhabdoid tumor 16 | 5,112
non-small cell lung cancer 16 | 2,890
osteosarcoma 16 | 7,950
primitive neuroectodermal tumor 16 | 3,035
Carcinoma 15 | 11,493
lung cancer 15 | 4,740
ovarian cancer 15 | 8,520
Breast cancer 14 | 3,578
adrenocortical carcinoma 14 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
invasive ductal carcinoma 14 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
ductal carcinoma in situ 11 | 1,745
lung adenocarcinoma 11 | 2,716
ependymoma 10 | 4,679
Endometriosis 9 | 540
adult high grade glioma 9 | 3,801
colon cancer 9 | 1,478
malignant mesothelioma 9 | 3,232
nasopharyngeal carcinoma 7 | 1,058
breast carcinoma 6 | 1,638
pancreatic cancer 6 | 2,398
pediatric high grade glioma 6 | 1,064
Kidney cancer 5 | 2,613
Atopic dermatitis 4 | 952
Multiple myeloma 4 | 1,332
Pick disease 4 | 1,894
Waldenstrons macroglobulinemia 4 | 765
pituitary cancer 4 | 1,972
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
Systemic scleroderma 3 | 60
acute myeloid leukemia 3 | 783
interstitial cystitis 3 | 2,312
oligodendroglioma 3 | 2,850
ulcerative colitis 3 | 1,819
Acquired metabolic disease 2 | 336
CREST Syndrome 2 | 16
Calcinosis 2 | 70
Dyskinesia of esophagus 2 | 10
Fanconi anemia 2 | 56
Gastric antral vascular ectasia 2 | 10
Retinoblastoma 2 | 19
Rheumatoid arthritis 2 | 1,191
Telangiectasis 2 | 36
active Crohn's disease 2 | 922
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung carcinoma 2 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
subependymal giant cell astrocytoma 2 | 2,287
Acute Promyelocytic Leukemia 1 | 40
Adenocarcinoma of lung 1 | 142
Amyotrophic lateral sclerosis 1 | 451
Brachydactyly 1 | 156
Disease Models, Animal 1 | 155
Hypoglycemia 1 | 152
Hypopituitarism 1 | 40
Laryngeal squamous cell carcinoma 1 | 3
Leukemia, Acute Myeloid 1 | 17
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Leukemia, Promyelocytic, Acute 1 | 36
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 1 | 16
Microcephaly 1 | 166
Multiple Sclerosis 1 | 540
Nance-Horan syndrome 1 | 25
Nephroblastoma 1 | 51
Omphalocele 1 | 24
Retinitis pigmentosa 11 1 | 59
Retinitis pigmentosa 24 1 | 15
Seckel syndrome 1 | 34
Spondylosis 1 | 16
Stomach Neoplasms 1 | 300
Type 1 diabetes mellitus 1 | 109
Vertebrobasilar insufficiency 1 | 9
Williams-Beuren syndrome 1 | 50
astrocytic glioma 1 | 2,597
atypical teratoid/rhabdoid tumor 1 | 357
cutaneous lupus erythematosus 1 | 1,057
cystic fibrosis and chronic rhinosinusitis 1 | 214
inflammatory breast cancer 1 | 286
medulloblastoma 1 | 720
mucosa-associated lymphoid tissue lymphoma 1 | 484
non-small cell lung carcinoma 1 | 317
pancreatic carcinoma 1 | 562
posterior fossa group A ependymoma 1 | 468
primary pancreatic ductal adenocarcinoma 1 | 1,109
tuberculosis 1 | 2,010
tuberculosis and treatment for 3 months 1 | 179
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 29 | 16,909
Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 28 | 12,091
Epigenetic 1 | 242

GO Process

CENP-A containing nucleosome a... 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Centromere protein O CENPO Tbio Non-IDG -0.67552 5.22 124
Histone H3-like centromeric protein A CENPA Tbio Non-IDG -2.73322 567.0 386
Mis18-binding protein 1 MIS18BP1 Tdark Non-IDG -1.12057 12.9 47
Protein Mis18-alpha MIS18A Tbio Non-IDG -2.14017 104.5 47
Histone-binding protein RBBP4 RBBP4 Tbio Non-IDG -1.71209 53.9 310
Centromere protein X CENPX Tbio Non-IDG -0.81813 5.70 33
Protein Mis18-beta OIP5 Tbio Non-IDG -1.25737 17.7 65
Holliday junction recognition protein HJURP Tbio Non-IDG -1.45205 24.7 91
Centromere protein W CENPW Tbio Non-IDG -1.12039 16.1 51
Centromere protein H CENPH Tbio Non-IDG -1.50805 34.6 232