Development Level

Tbio 69 | 11,445
Tchem 13 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to t... 7 | 278
preweaning lethality, incomple... 5 | 499
abnormal embryo size 4 | 220
hypoactivity 4 | 132
abnormal forebrain development 2 | 20
abnormal hindbrain development 2 | 16
abnormal midbrain development 2 | 20
abnormal neural tube closure 2 | 46
decreased body weight 2 | 161
decreased circulating creatini... 2 | 39
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
edema 2 | 59
enlarged heart 2 | 210
female infertility 2 | 60
increased hematocrit 2 | 46
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased startle reflex 2 | 112
male infertility 2 | 123
pale yolk sac 2 | 25
pallor 2 | 34
prenatal lethality prior to he... 2 | 87
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal eyelid morphology 1 | 7
abnormal gait 1 | 69
abnormal head size 1 | 6
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal placement of pupils 1 | 6
abnormal testis morphology 1 | 43
absent seminal vesicle 1 | 4
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased B cell number 1 | 5
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating potassiu... 1 | 29
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
irregularly shaped pupil 1 | 7
microphthalmia 1 | 26
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
short tibia 1 | 97
small uterus 1 | 3
thrombocytopenia 1 | 56
trunk curl 1 | 16

Disease

Carcinoma 54 | 11,493
ovarian cancer 43 | 8,520
glioblastoma 33 | 5,792
Cancer 32 | 2,499
atypical teratoid / rhabdoid tumor 32 | 5,112
osteosarcoma 32 | 7,950
psoriasis 30 | 6,694
ependymoma 28 | 4,679
medulloblastoma, large-cell 28 | 6,241
lung cancer 25 | 4,740
adult high grade glioma 24 | 3,801
non-small cell lung cancer 23 | 2,890
invasive ductal carcinoma 22 | 2,951
lung adenocarcinoma 20 | 2,716
malignant mesothelioma 20 | 3,232
Astrocytoma, Pilocytic 19 | 3,081
Breast cancer 19 | 3,578
lung carcinoma 19 | 2,843
oligodendroglioma 19 | 2,850
group 3 medulloblastoma 18 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
pancreatic cancer 17 | 2,398
breast carcinoma 16 | 1,638
subependymal giant cell astrocytoma 16 | 2,287
cystic fibrosis 15 | 1,696
ductal carcinoma in situ 15 | 1,745
group 4 medulloblastoma 15 | 1,855
interstitial cystitis 15 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
Autosomal recessive predisposition 13 | 1,442
Pick disease 13 | 1,894
astrocytic glioma 13 | 2,597
colon cancer 13 | 1,478
pituitary cancer 13 | 1,972
ulcerative colitis 13 | 1,819
diabetes mellitus 12 | 1,728
primitive neuroectodermal tumor 12 | 3,035
Brachydactyly 11 | 156
Kidney cancer 11 | 2,613
Rheumatoid arthritis 11 | 1,191
primary pancreatic ductal adenocarcinoma 11 | 1,109
tuberculosis 11 | 2,010
Cleft Palate 10 | 271
Atopic dermatitis 9 | 952
Cryptorchidism 9 | 296
Orbital separation excessive 9 | 244
Osteoporosis 9 | 363
Short stature 9 | 531
active Crohn's disease 9 | 922
adrenocortical carcinoma 9 | 1,428
juvenile dermatomyositis 9 | 1,187
Anemia 8 | 365
Craniofacial Abnormalities 8 | 151
Fibrodysplasia ossificans progressiva 8 | 17
Osteoarthritis 8 | 184
acute myeloid leukemia 8 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
cutaneous lupus erythematosus 8 | 1,057
gastric carcinoma 8 | 807
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Bilateral fifth finger clinodactyly 7 | 110
Cleft Lip 7 | 141
Cognitive delay 7 | 608
Congenital deafness 7 | 185
Congenital heart disease 7 | 93
Curvature of little finger 7 | 110
Deafness 7 | 198
Exophthalmos 7 | 112
Global developmental delay 7 | 608
Hearing Loss, Partial 7 | 185
Hereditary hemorrhagic telangiectasia 7 | 13
Liver Cirrhosis, Experimental 7 | 769
Mental and motor retardation 7 | 608
Schizophrenia 7 | 1,160
Telangiectasis 7 | 36
acute quadriplegic myopathy 7 | 1,158
astrocytoma 7 | 1,146
hearing impairment 7 | 199
Acquired scoliosis 6 | 281
Breast Neoplasms 6 | 445
Craniosynostosis 6 | 74
Curvature of spine 6 | 282
Decreased projection of midface 6 | 105
Down syndrome 6 | 499
Endometriosis 6 | 540
Heart disease 6 | 306
Hypertensive disease 6 | 292
Hypotrophic midface 6 | 105
Infertility 6 | 188
Intellectual disability 6 | 1,016
Midface retrusion 6 | 105
Myopia 6 | 176
Prominent eyes 6 | 96
Prominent globes 6 | 96
Prostatic Neoplasms 6 | 495
Protruding eyes 6 | 96
Right atrial isomerism 6 | 29
Small midface 6 | 105
sarcoidosis 6 | 370

Tissue

Endocrine System 83 | 18,159
Digestive Tract 81 | 17,369
Skin and soft tissues 81 | 17,230
Female tissues 80 | 17,400
Liver and Pancreas 79 | 16,750
Male tissues 78 | 17,142
Blood and immune system 77 | 16,909
Nervous System 77 | 16,725
Urinary Tract 77 | 16,678
Respiratory system 75 | 16,393
Cardiovascular System 74 | 15,192

Target Family

Non-IDG 51 | 12,091
Transcription Factor 15 | 1,400
Kinase 10 | 634
Enzyme 6 | 4,145
Transporter 2 | 473
Ion Channel 1 | 344

GO Process

BMP signaling pathway 85 | 85
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable ATP-dependent RNA helicase DDX5 DDX5 Tbio Enzyme -2.08566 121.1 344
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Protein FAM83G FAM83G Tbio Non-IDG -1.07402 11.5 72
Transmembrane protein 100 TMEM100 Tbio Non-IDG -0.92226 8.79 100
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Ubiquitin carboxyl-terminal hydrolase 15 USP15 Tbio Enzyme -1.64742 41.6 242
Follistatin-related protein 1 FSTL1 Tbio Non-IDG -1.98038 117.5 265
Brachyury protein TBXT Tbio Transcription Factor -2.24737 158.4 337