Development Level

Tbio 46 | 11,445
Tchem 8 | 1,598
Tclin 8 | 613
Tdark 2 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased bone mineral density 2 | 126
abnormal bone mineralization 1 | 38
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal vibrissa morphology 1 | 25
decreased IgG3 level 1 | 1
decreased body weight 1 | 161
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased bone mineral density 1 | 72
increased erythrocyte cell num... 1 | 39
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499

Disease

Cancer 37 | 2,499
Carcinoma 36 | 11,493
osteosarcoma 32 | 7,950
psoriasis 23 | 6,694
glioblastoma 20 | 5,792
malignant mesothelioma 20 | 3,232
ovarian cancer 20 | 8,520
tuberculosis 19 | 2,010
lung cancer 18 | 4,740
Rheumatoid arthritis 15 | 1,191
Kidney cancer 14 | 2,613
group 3 medulloblastoma 14 | 4,104
Autosomal recessive predisposition 13 | 1,442
Diarrhea 13 | 253
medulloblastoma, large-cell 13 | 6,241
Arthritis 12 | 290
ependymoma 12 | 4,679
ulcerative colitis 12 | 1,819
Multiple Sclerosis 11 | 540
interstitial cystitis 11 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
primitive neuroectodermal tumor 11 | 3,035
subependymal giant cell astrocytoma 11 | 2,287
Conjunctivitis 10 | 53
Failure to gain weight 10 | 365
Fatigue 10 | 182
Fever 10 | 138
Pediatric failure to thrive 10 | 365
atypical teratoid / rhabdoid tumor 10 | 5,112
diabetes mellitus 10 | 1,728
Anemia 9 | 365
Breast cancer 9 | 3,578
Hepatitis B 9 | 108
Hypersensitivity reaction type II disease 9 | 253
Multiple myeloma 9 | 1,332
Pneumonia 9 | 174
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung adenocarcinoma 9 | 2,716
pituitary cancer 9 | 1,972
Asthma 8 | 385
Conjunctivitis, recurrent 8 | 37
Increased susceptibility to bacterial infections 8 | 42
Lymphoid leukemia 8 | 160
Prone to bacterial infection 8 | 42
Recurrent bacterial infection 8 | 42
Recurrent respiratory infections 8 | 141
Schizophrenia 8 | 1,160
Thrombocytopenia 8 | 197
adult high grade glioma 8 | 3,801
lung carcinoma 8 | 2,843
primary Sjogren syndrome 8 | 735
Agammaglobulinemia 7 | 34
Crohn's disease 7 | 321
Hepatitis 7 | 67
Hepatitis C 7 | 94
Immunologic Deficiency Syndromes 7 | 113
Infantile onset 7 | 238
Inflammatory bowel disease 7 | 151
Influenza 7 | 142
Melanoma 7 | 711
Meningitis 7 | 67
Severe combined immunodeficiency 7 | 51
Sinusitis 7 | 65
cutaneous lupus erythematosus 7 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
invasive ductal carcinoma 7 | 2,951
non-small cell lung cancer 7 | 2,890
oligodendroglioma 7 | 2,850
sarcoidosis 7 | 370
Chronic otitis media 6 | 52
Colitis 6 | 54
Immune system cancer 6 | 140
Infection of bone 6 | 19
Kidney disease 6 | 430
Leukopenia 6 | 72
Neuropathy 6 | 261
Osteomyelitis 6 | 42
Splenomegaly 6 | 190
acute myeloid leukemia 6 | 783
breast carcinoma 6 | 1,638
cystic fibrosis 6 | 1,696
ductal carcinoma in situ 6 | 1,745
ear infection chronic 6 | 52
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Amyotrophic lateral sclerosis 5 | 451
Astrocytoma, Pilocytic 5 | 3,081
Cryoglobulinemia 5 | 18
Dermatitis 5 | 157
Encephalitis 5 | 64
Hypereosinophilic syndrome 5 | 71
Liver Cirrhosis, Experimental 5 | 769
Mental Depression 5 | 333
Pick disease 5 | 1,894
Renal Cell Carcinoma 5 | 214
Urticaria 5 | 67
Vasculitis 5 | 80
Weight decreased 5 | 103
acute quadriplegic myopathy 5 | 1,158
astrocytic glioma 5 | 2,597
periodontitis 5 | 293

Tissue

Blood and immune system 53 | 16,909
Endocrine System 50 | 18,159
Male tissues 49 | 17,142
Skin and soft tissues 49 | 17,230
Urinary Tract 48 | 16,678
Digestive Tract 47 | 17,369
Liver and Pancreas 47 | 16,750
Female tissues 46 | 17,400
Nervous System 46 | 16,725
Respiratory system 44 | 16,393
Cardiovascular System 43 | 15,192

Target Family

Non-IDG 36 | 12,091
Transcription Factor 11 | 1,400
Enzyme 6 | 4,145
Epigenetic 5 | 242
Kinase 4 | 634
GPCR 2 | 408

GO Process

B cell differentiation 64 | 64
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adhesion G protein-coupled receptor G3 ADGRG3 Tchem GPCR -0.68899 5.73 99
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Zinc finger and BTB domain-containing protein 1 ZBTB1 Tbio Transcription Factor -0.66768 5.75 59
Krueppel-like factor 6 KLF6 Tbio Transcription Factor -2.37304 253.6 161
DDB1- and CUL4-associated factor 1 DCAF1 Tbio Non-IDG -1.71452 57.7 62
Interferon alpha-1/13 IFNA13 Tbio Non-IDG -3.87160 7663.4 500
Interferon alpha-17 IFNA17 Tbio Non-IDG -2.39299 231.1 56
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.41628 245.1 733
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461