Development Level

Tbio 16 | 11,445
Tdark 6 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased circulating fructosa... 2 | 30
abnormal coat-hair pigmentatio... 1 | 64
abnormal hair texture 1 | 4
decreased body weight 1 | 161
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
fusion of vertebral arches 1 | 7
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
preweaning lethality, incomple... 1 | 499
vertebral fusion 1 | 23

Disease

ovarian cancer 11 | 8,520
psoriasis 9 | 6,694
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
glioblastoma 7 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
Breast cancer 5 | 3,578
Carcinoma 5 | 11,493
Waldenstrons macroglobulinemia 5 | 765
Wiskott-Aldrich syndrome 5 | 30
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
juvenile dermatomyositis 5 | 1,187
lung cancer 5 | 4,740
pancreatic cancer 5 | 2,398
Astrocytoma, Pilocytic 4 | 3,081
Multiple myeloma 4 | 1,332
Paraplegia 4 | 74
Ritscher-Schinzel syndrome 4 | 11
astrocytic glioma 4 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary Sjogren syndrome 4 | 735
primary pancreatic ductal adenocarcinoma 4 | 1,109
primitive neuroectodermal tumor 4 | 3,035
Duchenne muscular dystrophy 3 | 601
Pick disease 3 | 1,894
acute quadriplegic myopathy 3 | 1,158
diabetes mellitus 3 | 1,728
group 3 medulloblastoma 3 | 4,104
Cancer 2 | 2,499
Galloway-Mowat syndrome 2 | 15
Schizophrenia 2 | 1,160
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
group 4 medulloblastoma 2 | 1,855
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
posterior fossa group A ependymoma 2 | 468
tuberculosis and treatment for 6 months 2 | 409
ulcerative colitis 2 | 1,819
Angelman syndrome 1 | 34
Astigmatism 1 | 54
Atelosteogenesis 1 | 5
Autistic Disorder 1 | 364
Barrett's esophagus 1 | 182
Coarse facial features 1 | 108
Constipation 1 | 181
Contracture 1 | 96
Contracture of joint 1 | 93
Dilated ventricles (finding) 1 | 121
Distal arthrogryposis 1 | 42
Dyschezia 1 | 135
Flexion contracture 1 | 93
Flexion contractures of joints 1 | 93
Hyperinsulinism 1 | 133
Hyperopia 1 | 70
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Hypoplastic feet 1 | 66
Hypoventilation 1 | 8
Infertility 1 | 188
Isolated cases 1 | 72
Long narrow head 1 | 75
Motor delay 1 | 147
Myopia 1 | 176
Narrow cranium shape 1 | 75
Narrow forehead 1 | 34
Narrow head shape 1 | 75
Narrow skull shape 1 | 75
Neonatal Hypotonia 1 | 64
No development of motor milestones 1 | 147
Pain agnosia 1 | 104
Periventricular nodular heterotopia 1 | 30
Polycystic kidney disease 2 1 | 11
Prader-Willi syndrome 1 | 48
Recurrent respiratory infections 1 | 141
Reduced fetal movement 1 | 51
Respiratory Depression 1 | 10
Specific learning disability 1 | 47
Thickened facial skin with coarse facial features 1 | 108
Thin upper lip vermilion 1 | 67
Turridolichocephaly 1 | 75
Usher syndrome type 1 1 | 10
facioscapulohumeral dystrophy 1 | 288
limb girdle muscular dystrophy 2B 1 | 40
non-inflammatory breast cancer 1 | 66

Tissue

Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678
Cardiovascular System 16 | 15,192

Target Family

Non-IDG 21 | 12,091
Enzyme 1 | 4,145

GO Process

Arp2-3 complex-mediated actin ... 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MAGE-like protein 2 MAGEL2 Tbio Non-IDG -1.95242 83.8 86
Ras GTPase-activating-like protein IQGAP2 IQGAP2 Tbio Enzyme -1.40687 25.2 146
Junction-mediating and -regulatory protein JMY Tbio Non-IDG -1.26760 21.2 162
Actin-related protein 2 ACTR2 Tbio Non-IDG -1.88412 78.5 211
Putative WAS protein family homolog 4 WASH4P Tdark Non-IDG 0.00000 0
WAS protein family homolog 2 WASH2P Tdark Non-IDG -0.28297 2.17 0
Actin-related protein 2/3 complex subunit 2 ARPC2 Tbio Non-IDG -1.31089 16.9 270
Actin-related protein 2/3 complex subunit 4 ARPC4 Tbio Non-IDG -1.00650 0.00000 120
WASP homolog-associated protein with actin, membranes and microtubules WHAMM Tbio Non-IDG -0.85342 12.1 24
Putative WAS protein family homolog 3 WASH3P Tbio Non-IDG -0.28297 2.17 0