Development Level

Tbio 18 | 11,651
Tchem 3 | 1,388
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 3 | 220
embryonic lethality prior to o... 2 | 239
preweaning lethality, incomple... 2 | 499
abnormal QT variability 1 | 10
abnormal behavior 1 | 298
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
edema 1 | 59
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased body temperature 1 | 9
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased hemoglobin content 1 | 45
prenatal lethality 1 | 28

Disease

Carcinoma 19 | 11,493
ovarian cancer 18 | 8,520
osteosarcoma 16 | 7,950
group 3 medulloblastoma 12 | 4,104
medulloblastoma, large-cell 12 | 6,241
primitive neuroectodermal tumor 11 | 3,035
Intellectual disability 10 | 1,016
psoriasis 10 | 6,694
glioblastoma 9 | 5,792
atypical teratoid / rhabdoid tumor 8 | 5,112
ependymoma 8 | 4,679
lung cancer 8 | 4,740
Cancer 7 | 2,499
astrocytoma 7 | 1,146
lung adenocarcinoma 7 | 2,716
Breast cancer 6 | 3,578
Kidney cancer 6 | 2,613
Multiple myeloma 6 | 1,332
pediatric high grade glioma 6 | 1,064
Acquired scoliosis 5 | 281
Broad flat nasal bridge 5 | 236
Coffin-Siris syndrome 5 | 17
Cognitive delay 5 | 608
Cryptorchidism 5 | 296
Curvature of spine 5 | 282
Dull intelligence 5 | 645
Epilepsy 5 | 792
Global developmental delay 5 | 608
Low intelligence 5 | 645
Macrostomia 5 | 72
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Muscle hypotonia 5 | 571
Nasal bridge wide 5 | 236
Poor school performance 5 | 645
Schizophrenia 5 | 1,160
Seizures 5 | 596
Short stature 5 | 531
Small head 5 | 374
acute myeloid leukemia 5 | 783
diabetes mellitus 5 | 1,728
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
Abnormality of cardiovascular system morphology 4 | 23
Aplasia/Hypoplasia of the distal phalanx of the 5th finger 4 | 5
Astrocytoma, Pilocytic 4 | 3,081
Bushy eyebrows 4 | 49
Cerebellar hypoplasia and atrophy 4 | 41
Coarse facial features 4 | 108
Concave bridge of nose 4 | 195
Congenital deafness 4 | 185
Dandy-Walker Syndrome 4 | 39
Deafness 4 | 198
Dental abnormalities 4 | 60
Depressed nasal bridge 4 | 195
Depressed nasal ridge 4 | 51
Depressed nasal root/bridge 4 | 195
Endometriosis 4 | 540
Feeding difficulties in infancy 4 | 175
Fetal Growth Retardation 4 | 189
Full lower lip 4 | 64
Generalized hirsutism 4 | 36
Hearing Loss, Partial 4 | 185
Hypoplastic fifth fingernail 4 | 5
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Joint hyperflexibility 4 | 78
Liver cancer 4 | 604
Long eyelashes 4 | 37
Nystagmus 4 | 317
Patella aplasia-hypoplasia 4 | 12
Prominent lower lip 4 | 64
Recurrent respiratory infections 4 | 141
Rheumatoid arthritis 4 | 1,191
Short distal phalanges 4 | 50
Slow-growing hair 4 | 19
Strabismus 4 | 270
Thickened facial skin with coarse facial features 4 | 108
Tooth Abnormalities 4 | 69
Waldenstrons macroglobulinemia 4 | 765
dermatomyositis 4 | 966
group 4 medulloblastoma 4 | 1,855
hearing impairment 4 | 199
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
malignant mesothelioma 4 | 3,232
spina bifida 4 | 1,074
Pick disease 3 | 1,894
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
pancreatic cancer 3 | 2,398
Bipolar Disorder 2 | 666
adult high grade glioma 2 | 3,801
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Blood and immune system 23 | 16,909
Cardiovascular System 23 | 15,192
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678

Target Family

Non-IDG 9 | 12,091
Epigenetic 6 | 242
Transcription Factor 6 | 1,400
TF/Epigenetic 2 | 38

GO Process

ATP-dependent chromatin remode... 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcriptional repressor p66-beta GATAD2B Tbio Transcription Factor -1.00210 9.37 215
Chromodomain-helicase-DNA-binding protein 8 CHD8 Tbio Epigenetic -1.64766 47.4 81
Histone-binding protein RBBP4 RBBP4 Tbio Non-IDG -1.71209 53.9 310
Histone deacetylase 1 HDAC1 Tclin Epigenetic -3.03775 954.3 1201
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 SMARCB1 Tbio Non-IDG -2.77635 619.8 379
Transcription activator BRG1 SMARCA4 Tchem Epigenetic -2.86389 713.1 332
Actin, cytoplasmic 1 ACTB Tbio Non-IDG -3.52930 2830.7 1251
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 SMARCE1 Tbio Transcription Factor -1.51153 35.7 270
Actin-like protein 6A ACTL6A Tbio Non-IDG -1.45479 28.3 286
SWI/SNF complex subunit SMARCC2 SMARCC2 Tbio TF/Epigenetic -1.27787 15.2 140