Development Level

Tbio 5 | 11,445

IMPC Phenotype

decreased circulating insulin ... 1 | 76
decreased fasted circulating g... 1 | 65

Disease

Carcinoma 3 | 11,493
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
primitive neuroectodermal tumor 3 | 3,035
Liver Cirrhosis, Experimental 2 | 769
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
lung adenocarcinoma 2 | 2,716
ovarian cancer 2 | 8,520
3-4 toe syndactyly 1 | 3
Abnormality of the nasopharynx 1 | 9
Abnormality of the thorax 1 | 19
Absence of a tooth 1 | 6
Acquired cubitus valgus 1 | 18
Anhedonia 1 | 27
Arrhythmias, Cardiac 1 | 19
Atrioventricular Septal Defect 1 | 22
Basal ganglia calcification 1 | 27
Bony paranasal bossing 1 | 1
Broad alveolar processes of jaw 1 | 3
Broad alveolar ridges 1 | 3
Broad long bones 1 | 5
Club-shaped distal femora 1 | 1
Common atrioventricular canal 1 | 2
Congenital alopecia totalis 1 | 2
Congenital hypoplasia of aortic arch 1 | 2
Coronary aneurysm 1 | 4
Craniofacial hyperostosis 1 | 11
Craniometaphyseal dysplasia 1 | 5
Curly hair (finding) 1 | 14
Delayed eruption of permanent teeth 1 | 8
Diaphragmatic Hernia 1 | 40
Dry hair 1 | 7
Dystrophic fingernails 1 | 18
Enlargement of craniofacial bones 1 | 11
Enlargement of facial bones 1 | 2
Enlargement of skull bones 1 | 7
Erythrokeratodermia variabilis 1 | 10
Excessive growth of skull bones 1 | 7
Fifth finger camptodactyly 1 | 3
Fingernail dysplasia 1 | 6
First degree atrioventricular block 1 | 5
Fleshy earlobes 1 | 8
Hallermann's Syndrome 1 | 1
Hallermann-Streiff syndrome 1 | 8
Hearing Loss, Mixed Conductive-Sensorineural 1 | 12
Hernia, Diaphragmatic 1 | 40
Hyperkeratosis, generalized 1 | 14
Hyperostosis of cranial vault 1 | 7
Hyperostosis of facial bones 1 | 2
Hyperplasia of columella 1 | 4
Hyperplasia of permanent maxillary central incisor 1 | 3
Hypertrophy of cranial bones 1 | 7
Hypertrophy of craniofacial bones 1 | 11
Hypertrophy of facial bones 1 | 2
Hypertrophy of permanent maxillary central incisor 1 | 3
Hypoplastic Left Heart Syndrome 1 | 14
Increased ossification of facial bones 1 | 2
Increased size of permanent maxillary central incisor 1 | 3
Long nose 1 | 15
Mild global developmental delay 1 | 14
Mitochondrial myopathy 1 | 26
Myocardial Reperfusion Injury 1 | 37
Narrow nose 1 | 20
Nasal congestion (finding) 1 | 2
Nasal obstruction present finding 1 | 3
Neurogenic Urinary Bladder 1 | 6
Oculo-dento-digital syndrome 1 | 1
Oculodentodigital dysplasia 1 | 14
Ostium primum atrial septal defect 1 | 3
Paraparesis 1 | 6
Partial atrioventricular canal 1 | 5
Patchy palmoplantar keratoderma 1 | 3
Persistent pupillary membranes 1 | 1
Photosensitivity of skin 1 | 51
Pinched bridge of nose 1 | 14
Pinched nasal bridge 1 | 14
Prominent epicanthal folds 1 | 3
Prominent, protruding upper incisors 1 | 3
Psychomotor retardation, mild 1 | 14
Pyle metaphyseal dysplasia 1 | 8
Rhizomelic chondrodysplasia punctata 1 | 11
Schwartz-Lelek syndrome 1 | 2
Selective tooth agenesis 1 | 6
Short fifth finger 1 | 9
Short middle phalanx of the 5th finger 1 | 13
Slow-growing hair 1 | 19
Splayed metaphyses 1 | 19
Thick craniofacial bones 1 | 11
Thick skull bones 1 | 7
Thin anteverted nares 1 | 1
Thin hypoplastic alae nasi 1 | 51
Tooth hypoplasia 1 | 7
Vertebral hyperostosis 1 | 1
Wide columella 1 | 4

Tissue

Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Cardiovascular System 4 | 15,192

Target Family

Transporter 3 | 473
Ion Channel 1 | 344
Non-IDG 1 | 12,091

GO Process

ATP transport 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial coenzyme A transporter SLC25A42 SLC25A42 Tbio Transporter -0.53750 4.06 29
Peroxisomal membrane protein PMP34 SLC25A17 Tbio Transporter -2.14978 108.6 79
Calcium-binding mitochondrial carrier protein SCaMC-1 SLC25A24 Tbio Transporter -0.76501 6.30 69
Calcium homeostasis modulator protein 1 CALHM1 Tbio Ion Channel -1.71853 53.7 94
Gap junction alpha-1 protein GJA1 Tbio Non-IDG -3.59195 4122.5 889