Development Level

Tbio 17 | 11,445
Tdark 4 | 6,588
Tchem 3 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
cardiovascular system phenotyp... 1 | 36
decreased circulating bilirubi... 1 | 19
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased or absent threshold ... 1 | 101
short tibia 1 | 97
small adrenal glands 1 | 16
small lymph nodes 1 | 1

Disease

Carcinoma 17 | 11,493
ovarian cancer 16 | 8,520
psoriasis 11 | 6,694
Pick disease 9 | 1,894
atypical teratoid / rhabdoid tumor 8 | 5,112
ependymoma 8 | 4,679
glioblastoma 8 | 5,792
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
astrocytic glioma 7 | 2,597
Multiple myeloma 6 | 1,332
Osteopetrosis 6 | 43
lung cancer 6 | 4,740
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
Kidney cancer 5 | 2,613
adult high grade glioma 5 | 3,801
group 3 medulloblastoma 5 | 4,104
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
Cutis Laxa 4 | 39
invasive ductal carcinoma 4 | 2,951
subependymal giant cell astrocytoma 4 | 2,287
Anemia 3 | 365
Atrial Fibrillation 3 | 124
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Neuronal ceroid lipofuscinosis 3 | 28
Pediatric failure to thrive 3 | 365
Seizures 3 | 596
Spindle cell hemangioma 3 | 16
breast carcinoma 3 | 1,638
chronic rhinosinusitis 3 | 512
diabetes mellitus 3 | 1,728
lung adenocarcinoma 3 | 2,716
pancreatic cancer 3 | 2,398
tuberculosis 3 | 2,010
Bipolar Disorder 2 | 666
Broad flat nasal bridge 2 | 236
Chronic heart failure 2 | 46
Congestive heart failure 2 | 113
Dental caries 2 | 164
Dull intelligence 2 | 645
Enlarged vestibular aqueduct 2 | 10
Frontal bossing 2 | 157
Gaucher disease type 1 2 | 180
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hip joint varus deformity - observation 2 | 24
Hypertension 2 | 396
Intellectual disability 2 | 1,016
Kidney disease 2 | 430
Late tooth eruption 2 | 61
Low intelligence 2 | 645
Lymphoma, Follicular 2 | 18
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Metabolic acidosis 2 | 90
Nasal bridge wide 2 | 236
Nephrocalcinosis 2 | 35
Nystagmus 2 | 317
Osteoporosis 2 | 363
Poisoning by digitalis glycoside 2 | 8
Poor growth 2 | 114
Poor school performance 2 | 645
RENAL TUBULAR ACIDOSIS, DISTAL, AUTOSOMAL RECESSIVE 2 | 3
Retinitis pigmentosa 49 2 | 14
Rotting teeth 2 | 73
Sensorineural Hearing Loss (disorder) 2 | 284
Sensorineural hearing loss 2 | 106
Short stature 2 | 531
Very poor growth 2 | 114
Waldenstrons macroglobulinemia 2 | 765
astrocytoma 2 | 1,146
cystic fibrosis 2 | 1,696
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
medulloblastoma 2 | 720
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
Brachyonychia 1 | 6
Craniometaphyseal dysplasia 1 | 5
Cutis Laxa, Autosomal Recessive, Type IIA 1 | 1
Deep palmar crease 1 | 8
Facial paralysis 1 | 18
Fetal Membranes, Premature Rupture 1 | 5
Hypernasal voice 1 | 39
Hypoplasia of muscle 1 | 5
Nasal voice 1 | 39
Scapular weakness 1 | 23
Splayed metaphyses 1 | 19
Subcutaneous panniculitis-like T-cell lymphoma 1 | 16
Thin hypoplastic alae nasi 1 | 51
Winged scapula 1 | 23
Wrinkly skin syndrome 1 | 1

Tissue

Blood and immune system 27 | 16,909
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Urinary Tract 27 | 16,678
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Cardiovascular System 25 | 15,192

Target Family

Enzyme 24 | 4,145
Transporter 3 | 473

GO Process

ATP hydrolysis coupled proton ... 27 | 27
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
V-type proton ATPase 116 kDa subunit a isoform 4 ATP6V0A4 Tbio Enzyme -2.84949 692.2 90
V-type proton ATPase subunit E 1 ATP6V1E1 Tbio Enzyme -1.04091 10.7 137
V-type proton ATPase catalytic subunit A ATP6V1A Tbio Enzyme -1.83801 66.4 144
Sodium/potassium-transporting ATPase subunit alpha-2 ATP1A2 Tclin Transporter -2.12480 136.2 116
ATP synthase F(0) complex subunit C2, mitochondrial ATP5MC2 Tbio Enzyme -1.05013 10.1 122
V-type proton ATPase subunit E 2 ATP6V1E2 Tbio Enzyme -0.78312 6.53 60
V-type proton ATPase subunit F ATP6V1F Tbio Enzyme -0.91914 8.76 118
V-type proton ATPase subunit C 1 ATP6V1C1 Tbio Enzyme -1.31659 21.7 102
V-type proton ATPase subunit B, brain isoform ATP6V1B2 Tchem Enzyme -1.39933 24.1 157