Development Level

Tchem 5 | 1,598
Tbio 4 | 11,445

IMPC Phenotype

increased lean body mass 2 | 172
preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
vertebral fusion 1 | 23

Disease

Cancer 6 | 2,499
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
Carcinoma 5 | 11,493
psoriasis 5 | 6,694
Bipolar Disorder 4 | 666
Vascular disease 4 | 319
diabetes mellitus 4 | 1,728
glioblastoma 4 | 5,792
medulloblastoma, large-cell 4 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Asbestosis 3 | 20
Breast cancer 3 | 3,578
Carcinoma, Hepatocellular 3 | 228
Liver carcinoma 3 | 240
Myocardial Infarction 3 | 151
Obesity 3 | 678
Parkinson's disease 3 | 392
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
atypical teratoid / rhabdoid tumor 3 | 5,112
group 4 medulloblastoma 3 | 1,855
ulcerative colitis 3 | 1,819
Alzheimer's disease 2 | 658
Bipolar I disorder 2 | 23
Duchenne muscular dystrophy 2 | 601
Esophageal Squamous Cell Carcinoma 2 | 77
Fatty Liver 2 | 70
Fatty liver disease 2 | 103
Gaucher disease type 1 2 | 180
Multiple Sclerosis 2 | 540
Photodysphoria 2 | 121
Photophobia 2 | 121
Somatic mutation 2 | 61
Squamous cell carcinoma of esophagus 2 | 77
Toxic encephalopathy 2 | 141
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
ependymoma 2 | 4,679
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
non primary Sjogren syndrome sicca 2 | 891
Abnormal vertebral bodies 1 | 16
Absent eyebrow 1 | 13
Absent eyelashes 1 | 16
Achromatopsia 1 | 16
Agenesis of eyebrows 1 | 13
Alopecia areata 1 | 41
Amyloidosis 1 | 67
Aplasia of eyebrows 1 | 13
Aplasia of eyelashes 1 | 16
Asymmetry of the posterior cranium 1 | 20
Chromosome 19p13.13 deletion syndrome 1 | 5
Cloudy cornea 1 | 33
Color vision defect 1 | 33
Congenital anomaly of spine 1 | 16
Congenital hemivertebra 1 | 25
Congenital hypoplasia of kidney 1 | 32
Conjunctivitis 1 | 53
Conjunctivitis, recurrent 1 | 37
Convex nasal ridge 1 | 37
Corneal stromal opacities 1 | 33
Crimean-Congo hemorrhagic fever 1 | 9
Dystrophic fingernails 1 | 18
Ectodermal Dysplasia 1 | 14
Ectropion 1 | 38
Failure of development of eyelashes 1 | 16
Hematologic Neoplasms 1 | 22
Keratosis 1 | 37
Lassa fever 1 | 9
Macular degeneration 1 | 65
Madarosis of eyebrow 1 | 13
Multiple vertebral anomalies 1 | 16
Myxoid liposarcoma 1 | 6
Nonorganic psychosis 1 | 84
Nystagmus, continuous pendular 1 | 14
Olivopontocerebellar Atrophies 1 | 6
Onchocerciasis 1 | 10
Pendular Nystagmus 1 | 14
Phrynoderma 1 | 11
Plagiocephaly 1 | 20
Plagiocephaly, Nonsynostotic 1 | 20
Polyneuropathy 1 | 64
Respiratory Hypersensitivity 1 | 19
SPINOCEREBELLAR ATAXIA 17 1 | 9
Scarring alopecia of scalp 1 | 13
Scrapie 1 | 17
Shared Paranoid Disorder 1 | 5
Small testicle 1 | 75
Sparse eyebrow 1 | 42
Sparse eyelashes 1 | 31
Spinocerebellar ataxia type 17 1 | 7
Systemic scleroderma 1 | 60
Type 1 diabetes mellitus 1 | 109
Unilateral agenesis of kidney 1 | 20
Vesico-Ureteral Reflux 1 | 33
X- linked recessive 1 | 110

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Transcription Factor 4 | 1,400
Non-IDG 3 | 12,091
Enzyme 2 | 4,145

GO Process

ATF6-mediated unfolded protein... 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Endoplasmin HSP90B1 Tchem Non-IDG -2.76074 629.2 850
DNA damage-inducible transcript 3 protein DDIT3 Tchem Transcription Factor -2.94434 736.0 704
Membrane-bound transcription factor site-2 protease MBTPS2 Tbio Enzyme -1.94015 86.1 119
Membrane-bound transcription factor site-1 protease MBTPS1 Tchem Enzyme -1.49326 34.9 64
Cyclic AMP-dependent transcription factor ATF-6 beta ATF6B Tbio Transcription Factor -1.03459 8.22 6
78 kDa glucose-regulated protein HSPA5 Tchem Non-IDG -3.35010 2184.4 1074
Cyclic AMP-dependent transcription factor ATF-6 alpha ATF6 Tbio Transcription Factor -2.65391 415.0 407
Calreticulin CALR Tbio Non-IDG -3.19563 1544.2 778