Development Level

Tbio 21 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 2 | 220
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal hindbrain morphology 1 | 10
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
increased circulating aspartat... 1 | 15
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 17 | 8,520
Carcinoma 16 | 11,493
glioblastoma 13 | 5,792
medulloblastoma, large-cell 13 | 6,241
Acrodermatitis enteropathica 11 | 18
atypical teratoid / rhabdoid tumor 10 | 5,112
osteosarcoma 10 | 7,950
pancreatic cancer 8 | 2,398
ependymoma 7 | 4,679
lung adenocarcinoma 7 | 2,716
psoriasis 7 | 6,694
ulcerative colitis 7 | 1,819
active Crohn's disease 6 | 922
adult high grade glioma 6 | 3,801
group 3 medulloblastoma 6 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Breast cancer 5 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
non-small cell lung cancer 5 | 2,890
tuberculosis 5 | 2,010
Acquired metabolic disease 4 | 336
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Multiple myeloma 4 | 1,332
Respiratory Hypersensitivity 4 | 19
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
malignant mesothelioma 4 | 3,232
oligodendroglioma 4 | 2,850
primary pancreatic ductal adenocarcinoma 4 | 1,109
Alzheimer's disease 3 | 658
Parkinson's disease 3 | 392
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
esophageal adenocarcinoma 3 | 737
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035
Acrodermatitis 2 | 5
Alzheimer Disease 2 | 83
Bipolar Disorder 2 | 666
Duchenne muscular dystrophy 2 | 601
Dystonia 2 | 164
Endometriosis 2 | 540
Epidermodysplasia verruciformis 2 | 21
Hemochromatosis 2 | 54
Hepatomegaly 2 | 285
Insulinoma 2 | 24
Liver Cirrhosis, Experimental 2 | 769
Neoplasm Metastasis 2 | 168
Neurodegenerative disease 2 | 414
Osteoarthritis 2 | 184
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Tremor 2 | 113
Troyer syndrome 2 | 5
Type 2 diabetes mellitus 2 | 272
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,855
head and neck cancer 2 | 271
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
subependymal giant cell astrocytoma 2 | 2,287
Abnormal blistering of the skin 1 | 54
Abnormality of metabolism/homeostasis 1 | 134
Abnormality of the liver 1 | 21
Alopecia 1 | 115
Barrett's esophagus 1 | 182
Blister of skin 1 | 54
Breast Neoplasms 1 | 445
Congenital disorder of glycosylation 1 | 54
Ehlers-Danlos syndrome 1 | 43
Erythrocytosis 1 | 8
Esophageal Neoplasms 1 | 69
Esophageal Squamous Cell Carcinoma 1 | 77
Lethargy 1 | 77
Mammary Neoplasms 1 | 425
Mood swings 1 | 77
Photodysphoria 1 | 121
Photophobia 1 | 121
Polycythemia 1 | 25
Radioulnar synostosis 1 | 35
Schizophrenia, Catatonic 1 | 4
Skin bulla 1 | 54
Squamous cell carcinoma of esophagus 1 | 77
sarcoidosis 1 | 370

Tissue

Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Nervous System 22 | 16,725
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Blood and immune system 20 | 16,909
Male tissues 20 | 17,142
Urinary Tract 20 | 16,678
Cardiovascular System 17 | 15,192

Target Family

Transporter 22 | 473

GO Function

zinc ion transmembrane transpo... 22 | 22
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc transporter ZIP3 SLC39A3 Tbio Transporter -0.52290 3.15 87
Zinc transporter 1 SLC30A1 Tbio Transporter -2.12639 135.9 148
Zinc transporter ZIP10 SLC39A10 Tbio Transporter -1.20558 16.3 102
Zinc transporter 2 SLC30A2 Tbio Transporter -1.59498 39.4 26
Zinc transporter ZIP6 SLC39A6 Tbio Transporter -1.66663 50.0 172
Zinc transporter 8 SLC30A8 Tbio Transporter -2.20313 168.0 122
Zinc transporter ZIP2 SLC39A2 Tbio Transporter -1.63982 41.5 59
Zinc transporter 7 SLC30A7 Tbio Transporter -1.38652 25.4 42
Zinc transporter ZIP13 SLC39A13 Tbio Transporter -1.27212 14.9 48
Natural resistance-associated macrophage protein 2 SLC11A2 Tchem Transporter -2.53965 373.5 250