Development Level

Tbio 11 | 11,445

IMPC Phenotype

increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating total pr... 2 | 28
abnormal behavior 1 | 298
abnormal kidney morphology 1 | 65
decreased grip strength 1 | 116
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased total retina thickne... 1 | 4

Disease

Carcinoma 7 | 11,493
psoriasis 7 | 6,694
Brain Edema 5 | 50
Meniere's disease 5 | 24
Nephrogenic Diabetes Insipidus 5 | 16
Oligohydramnios 4 | 52
lung adenocarcinoma 4 | 2,716
pancreatic cancer 4 | 2,398
Cancer 3 | 2,499
Kidney disease 3 | 430
Polyhydramnios 3 | 108
Urinary tract obstruction 3 | 11
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
Autosomal recessive polycystic kidney disease 2 | 41
Constipation 2 | 181
Diabetes insipidus 2 | 18
Diarrhea 2 | 253
Down syndrome 2 | 499
Epilepsy 2 | 792
Hydrarthrosis 2 | 4
Hydrocephalus 2 | 152
Hypertension 2 | 396
Inappropriate ADH syndrome 2 | 5
Multiple Sclerosis 2 | 540
Neuromyelitis optica 2 | 18
Spinal Cord Injuries 2 | 8
Ureteral disease 2 | 3
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
mucosa-associated lymphoid tissue lymphoma 2 | 484
oligodendroglioma 2 | 2,850
ovarian cancer 2 | 8,520
pancreatic carcinoma 2 | 562
primary pancreatic ductal adenocarcinoma 2 | 1,109
Abnormal blistering of the skin 1 | 54
Acute Promyelocytic Leukemia 1 | 40
Anhidrosis 1 | 23
Animal Mammary Neoplasms 1 | 136
Anorexia 1 | 43
Arsenic Poisoning 1 | 62
Blister of skin 1 | 54
CATARACT 16, MULTIPLE TYPES 1 | 15
Carcinoma, Squamous Cell 1 | 110
Cardiomyopathies 1 | 110
Choledochal Cyst 1 | 9
Congestive heart failure 1 | 113
Dacryoadenitis 1 | 10
Dry eye syndrome 1 | 18
Edema, Cardiac 1 | 3
Encephalitis 1 | 64
Erythema 1 | 58
Esophageal Neoplasms 1 | 69
Fibrogenesis imperfecta ossium 1 | 2
Flushing 1 | 60
Hyperthyroidism 1 | 53
Hypokalemia 1 | 52
Impairment of urinary concentration 1 | 5
Intestinal tuberculosis 1 | 5
Irritable bowel syndrome 1 | 60
Irritation - emotion 1 | 68
Keratosis 1 | 37
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Leukemia, Promyelocytic, Acute 1 | 36
Lymphatic Metastasis 1 | 15
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Metabolic acidosis 1 | 90
Nausea and vomiting 1 | 97
Neonatal onset 1 | 21
Nuclear cataract 1 | 19
Nuclear non-senile cataract 1 | 18
Ovarian Neoplasms 1 | 102
Pain 1 | 103
Palmoplantar keratosis 1 | 74
Polyuria 1 | 23
Presbyopia 1 | 20
Pruritus 1 | 58
Pulmonary edema 1 | 17
Respiratory Failure 1 | 104
Salivary Gland Neoplasms 1 | 46
Septic Shock 1 | 5
Skin Neoplasms 1 | 69
Skin Ulcer 1 | 48
Skin bulla 1 | 54
Squamous cell carcinoma 1 | 129
inflammatory breast cancer 1 | 286
ovarian neoplasm 1 | 99

Tissue

Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Liver and Pancreas 11 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Blood and immune system 9 | 16,909
Female tissues 9 | 17,400
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192
Respiratory system 8 | 16,393

Target Family

Non-IDG 11 | 12,091

GO Function

water channel activity 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Aquaporin-6 AQP6 Tbio Non-IDG -1.52088 32.7 57
Aquaporin-9 AQP9 Tbio Non-IDG -2.13315 155.0 84
Aquaporin-8 AQP8 Tbio Non-IDG -2.06724 116.3 124
Aquaporin-10 AQP10 Tbio Non-IDG -1.23305 16.1 85
Aquaporin-7 AQP7 Tbio Non-IDG -2.03961 165.7 101
Aquaporin-4 AQP4 Tbio Non-IDG -3.33435 2159.1 358
Aquaporin-3 AQP3 Tbio Non-IDG -2.61717 403.0 260
Aquaporin-2 AQP2 Tbio Non-IDG -2.95328 957.7 394
Aquaporin-5 AQP5 Tbio Non-IDG -2.65367 454.1 197