Development Level

Tclin 36 | 612
Tbio 18 | 11,651
Tchem 3 | 1,388
Tdark 1 | 6,593

Collection

Ion Channel: IDG Consortium (T... 15 | 99
RFA-RM-18-021 15 | 328

IMPC Phenotype

abnormal behavior 2 | 298
enlarged heart 2 | 210
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
abnormal behavioral response t... 1 | 66
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
cardiovascular system phenotyp... 1 | 36
decreased fasted circulating g... 1 | 65
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged seminal vesicle 1 | 10
enlarged spleen 1 | 41
enlarged uterus 1 | 11
increased bone mineral content 1 | 108
increased circulating serum al... 1 | 22
increased mean platelet volume 1 | 45
kyphosis 1 | 5
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 52 | 11,493
Multiple Sclerosis 30 | 540
Eaton-Lambert syndrome 29 | 40
Kidney cancer 26 | 2,613
ependymoma 26 | 4,679
medulloblastoma, large-cell 25 | 6,241
glioblastoma 24 | 5,792
atypical teratoid / rhabdoid tumor 22 | 5,112
adult high grade glioma 21 | 3,801
Astrocytoma, Pilocytic 19 | 3,081
primitive neuroectodermal tumor 18 | 3,035
psoriasis 17 | 6,694
group 3 medulloblastoma 16 | 4,104
osteosarcoma 16 | 7,950
Epilepsy 15 | 792
oligodendroglioma 15 | 2,850
astrocytic glioma 14 | 2,597
lung cancer 14 | 4,740
lung carcinoma 11 | 2,843
malignant mesothelioma 11 | 3,232
ovarian cancer 11 | 8,520
Breast cancer 10 | 3,578
Intellectual disability 10 | 1,016
Long QT syndrome 10 | 39
Atrial Fibrillation 9 | 124
subependymal giant cell astrocytoma 9 | 2,287
Melanoma 8 | 711
pituitary cancer 8 | 1,972
Dull intelligence 7 | 645
Episodic ataxia 7 | 22
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Pick disease 7 | 1,894
Poor school performance 7 | 645
Seizures 7 | 596
Skin cancer 7 | 469
cystic fibrosis 7 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
Autosomal recessive predisposition 6 | 1,442
Brugada syndrome 6 | 29
Heart disease 6 | 306
Muscle hypotonia 6 | 571
Liver cancer 5 | 604
Schizophrenia 5 | 1,160
Type 2 diabetes mellitus 5 | 272
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
Abnormality of retinal pigmentation 4 | 111
Anteverted nostril 4 | 191
Bipolar Disorder 4 | 666
Difficulties with night vision 4 | 87
Electroretinogram abnormal 4 | 95
Myoclonus 4 | 74
Night Blindness 4 | 101
Nystagmus 4 | 317
Obesity 4 | 678
Paroxysmal atrial fibrillation 4 | 14
Partial Epilepsy Treatment Adjunct 4 | 16
Photodysphoria 4 | 121
Photophobia 4 | 121
Retinal pigment epithelial abnormality 4 | 111
Tonic - clonic seizures 4 | 44
adrenocortical carcinoma 4 | 1,428
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
Acquired metabolic disease 3 | 336
Angina Pectoris 3 | 32
Blind Vision 3 | 111
Blindness 3 | 88
Blindness, Legal 3 | 110
Broad flat nasal bridge 3 | 236
Cataract 3 | 297
Cerebellar Ataxia 3 | 304
Chronic heart failure 3 | 46
Cognitive delay 3 | 608
Diabetes Mellitus, Type 2 3 | 142
Enophthalmos 3 | 75
Glaucoma 3 | 239
Global developmental delay 3 | 608
Heart conduction disease 3 | 83
Hyperinsulinism 3 | 133
Lens Opacities 3 | 231
Long QT syndrome 1 3 | 20
Mental and motor retardation 3 | 608
Nasal bridge wide 3 | 236
Osteoporosis 3 | 363
Retinitis Pigmentosa 3 | 226
Sunken eyes 3 | 63
Tremor 3 | 113
Ventricular Fibrillation 3 | 17
active Crohn's disease 3 | 922
colon cancer 3 | 1,478
medulloblastoma 3 | 720
non-small cell lung cancer 3 | 2,890
progressive supranuclear palsy 3 | 676
sonic hedgehog group medulloblastoma 3 | 467
tuberculosis 3 | 2,010

Tissue

Endocrine System 56 | 18,159
Nervous System 52 | 16,725
Digestive Tract 50 | 17,369
Female tissues 50 | 17,400
Male tissues 50 | 17,142
Skin and soft tissues 50 | 17,230
Liver and Pancreas 45 | 16,750
Respiratory system 43 | 16,393
Urinary Tract 43 | 16,678
Blood and immune system 42 | 16,909
Cardiovascular System 37 | 15,192

Target Family

Ion Channel 56 | 344
Non-IDG 2 | 12,091

GO Function

voltage-gated potassium channe... 58 | 58
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
cGMP-gated cation channel alpha-1 CNGA1 Tchem Ion Channel -1.86143 69.8 62
Potassium voltage-gated channel subfamily D member 2 KCND2 Tclin Ion Channel -2.39309 245.7 317
Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 Tclin Ion Channel -2.65288 448.8 201
Voltage-gated potassium channel subunit beta-1 KCNAB1 Tbio Ion Channel -1.73441 56.3 218
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 HCN2 Tclin Ion Channel -1.16715 13.3 162
Cyclic nucleotide-gated olfactory channel CNGA2 Tbio Ion Channel -1.79780 61.2 204
Cyclic nucleotide-gated cation channel alpha-3 CNGA3 Tbio Ion Channel -1.95614 94.8 67
Potassium voltage-gated channel subfamily A member 10 KCNA10 Tclin Ion Channel -1.09844 13.3 65
Potassium voltage-gated channel subfamily C member 1 KCNC1 Tclin Ion Channel -2.46163 275.7 308
Potassium voltage-gated channel subfamily A member 3 KCNA3 Tclin Ion Channel -2.69107 522.2 286