Development Level

Tbio 4 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal heart morphology 1 | 162
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
enlarged heart 1 | 210
increased circulating alanine ... 1 | 13

Disease

Carcinoma 3 | 11,493
Hyperparathyroidism 3 | 48
Osteoporosis 3 | 363
Rickets 3 | 49
cystic fibrosis 3 | 1,696
Chronic obstructive pulmonary disease 2 | 184
Hypertension 2 | 396
Hypoparathyroidism 2 | 41
Hypophosphatemia 2 | 40
Kidney Diseases 2 | 114
Kidney disease 2 | 430
Osteomalacia 2 | 35
Schizophrenia 2 | 1,160
atypical teratoid / rhabdoid tumor 2 | 5,112
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
Anemia, hypochromic microcytic 1 | 2
Anodontia 1 | 12
Arteriosclerosis 1 | 11
Atherosclerosis 1 | 291
Bone Diseases, Metabolic 1 | 14
Brachycephaly 1 | 88
Broad cranium shape 1 | 88
Calcinosis 1 | 70
Chemical and Drug Induced Liver Injury 1 | 195
Congenital Heart Defects 1 | 58
Coronary artery disease 1 | 268
Craniofacial Abnormalities 1 | 151
Dermatologic disorders 1 | 93
Developmental absence of tooth 1 | 7
Developmental regression 1 | 95
Disease Models, Animal 1 | 155
Emphysema 1 | 12
Eye disease 1 | 62
Fractures, Bone 1 | 13
Generalized osteopenia 1 | 99
Graves Disease 1 | 11
Griscelli syndrome type 3 1 | 13
Hearing Loss, Sensorineural 1 | 11
Heart Defects, Congenital 1 | 37
Hepatic encephalopathy 1 | 27
Hernia, Inguinal 1 | 89
Hip Dislocation, Congenital 1 | 48
Hypercalcemia 1 | 59
Hyperphosphatemia 1 | 32
Hyperphosphatemia (disorder) 1 | 17
Hypocalcemia 1 | 32
Hypochromic anemia 1 | 9
Infertility 1 | 188
Iron-Refractory Iron Deficiency Anemia 1 | 15
Laterally sparse eyebrows 1 | 12
Learning Disorders 1 | 29
Liver Cirrhosis 1 | 181
Liver Cirrhosis, Experimental 1 | 769
Liver Failure, Acute 1 | 29
Liver disease 1 | 237
Loss of developmental milestones 1 | 95
Low posterior hairline 1 | 52
Lung Neoplasms 1 | 232
Lung diseases 1 | 50
Memory Disorders 1 | 40
Mental deterioration in childhood 1 | 95
Metabolic Bone Disorder 1 | 11
Microcytic hypochromic anemia (disorder) 1 | 10
Multiple Sclerosis 1 | 540
Myopia 1 | 176
Nance-Horan syndrome 1 | 25
Neurodegenerative disease 1 | 414
Neurodevelopmental regression 1 | 95
Osteopenia 1 | 99
Pathological accumulation of air in tissues 1 | 10
Plaque psoriasis 1 | 17
Psychomotor regression 1 | 95
Psychomotor regression beginning in infancy 1 | 95
Psychomotor regression in infants 1 | 95
Psychomotor regression, progressive 1 | 95
Psychomotor retardation, moderate 1 | 6
Schnyder Corneal Dystrophy 1 | 23
Sensorineural Hearing Loss (disorder) 1 | 284
Septic Shock 1 | 5
Severe myopia 1 | 22
Shock, Septic 1 | 6
Skin Diseases 1 | 71
Skin atrophy 1 | 16
Skin cancer 1 | 469
Sloping shoulders 1 | 21
Toxic encephalopathy 1 | 141
Wide skull shape 1 | 88
Wounds and Injuries 1 | 18
medulloblastoma 1 | 720
nutritional deficiency disease 1 | 9

Tissue

Digestive Tract 5 | 17,369
Female tissues 5 | 17,400
Cardiovascular System 4 | 15,192
Endocrine System 4 | 18,159
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678
Blood and immune system 3 | 16,909

Target Family

Non-IDG 3 | 12,091
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

GO Function

vitamin D binding 5 | 5
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calbindin CALB1 Tbio Non-IDG -3.31956 2149.9 287
Iroquois-class homeodomain protein IRX-5 IRX5 Tbio Transcription Factor -1.54616 33.4 196
Klotho KL Tbio Enzyme -2.86543 790.6 276
Protein S100-G S100G Tbio Non-IDG -2.39812 272.5 38
Vitamin D-binding protein GC Tchem Non-IDG -3.07485 1140.6 428