Development Level

Tbio 45 | 11,445
Tchem 17 | 1,598
Tclin 11 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased total body fat amoun... 3 | 207
preweaning lethality, incomple... 3 | 499
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased body weight 2 | 161
enlarged lymph nodes 2 | 37
increased circulating choleste... 2 | 66
increased leukocyte cell numbe... 2 | 47
preweaning lethality, complete... 2 | 979
abnormal anxiety-related respo... 1 | 1
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal hair texture 1 | 4
abnormal incisor color 1 | 3
abnormal incisor morphology 1 | 4
abnormal iris morphology 1 | 13
abnormal maxilla morphology 1 | 17
abnormal sensory capabilities-... 1 | 8
abnormal social-conspecific in... 1 | 3
abnormal spine curvature 1 | 9
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased cardiac muscle contr... 1 | 11
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating unsatura... 1 | 2
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged spleen 1 | 41
eyelids fail to open 1 | 3
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased grip strength 1 | 41
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
kyphosis 1 | 5
long tibia 1 | 25
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
small adrenal glands 1 | 16
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 52 | 11,493
Cancer 42 | 2,499
osteosarcoma 38 | 7,950
ovarian cancer 37 | 8,520
glioblastoma 32 | 5,792
interstitial cystitis 31 | 2,312
psoriasis 30 | 6,694
lung cancer 29 | 4,740
atypical teratoid / rhabdoid tumor 28 | 5,112
lung carcinoma 28 | 2,843
invasive ductal carcinoma 25 | 2,951
medulloblastoma, large-cell 24 | 6,241
non-small cell lung cancer 23 | 2,890
Breast cancer 21 | 3,578
malignant mesothelioma 21 | 3,232
pancreatic cancer 21 | 2,398
adult high grade glioma 20 | 3,801
ependymoma 20 | 4,679
group 3 medulloblastoma 20 | 4,104
lung adenocarcinoma 20 | 2,716
ulcerative colitis 20 | 1,819
Astrocytoma, Pilocytic 19 | 3,081
ductal carcinoma in situ 19 | 1,745
tuberculosis 19 | 2,010
diabetes mellitus 17 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
cutaneous lupus erythematosus 15 | 1,057
oligodendroglioma 15 | 2,850
Rheumatoid arthritis 14 | 1,191
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
primitive neuroectodermal tumor 14 | 3,035
Autosomal recessive predisposition 13 | 1,442
Kidney cancer 13 | 2,613
Multiple Sclerosis 13 | 540
Schizophrenia 13 | 1,160
Atherosclerosis 11 | 291
Human immunodeficiency virus infectious disease 11 | 138
Hypersensitivity reaction type II disease 11 | 253
colon cancer 11 | 1,478
nasopharyngeal carcinoma 11 | 1,058
primary pancreatic ductal adenocarcinoma 11 | 1,109
Anemia 10 | 365
breast carcinoma 10 | 1,638
cystic fibrosis 10 | 1,696
subependymal giant cell astrocytoma 10 | 2,287
Atopic dermatitis 9 | 952
Down syndrome 9 | 499
Kidney disease 9 | 430
Liver Cirrhosis, Experimental 9 | 769
astrocytic glioma 9 | 2,597
astrocytoma 9 | 1,146
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
primary Sjogren syndrome 9 | 735
Liver disease 8 | 237
Obesity 8 | 678
Thrombocytopenia 8 | 197
Waldenstrons macroglobulinemia 8 | 765
acute quadriplegic myopathy 8 | 1,158
dermatomyositis 8 | 966
gastric carcinoma 8 | 807
non-small cell lung carcinoma 8 | 317
spina bifida 8 | 1,074
Alzheimer's disease 7 | 658
Cerebrovascular disease 7 | 238
Coronary artery disease 7 | 268
Endometriosis 7 | 540
Malaria 7 | 160
Neoplasm Invasiveness 7 | 161
adrenocortical carcinoma 7 | 1,428
esophageal adenocarcinoma 7 | 737
pituitary cancer 7 | 1,972
sarcoidosis 7 | 370
Asthma 6 | 385
Dementia 6 | 175
Duchenne muscular dystrophy 6 | 601
Hepatomegaly 6 | 285
Lung disease 6 | 142
Multiple myeloma 6 | 1,332
Pick disease 6 | 1,894
Splenomegaly 6 | 190
Vascular disease 6 | 319
juvenile dermatomyositis 6 | 1,187
nephrosclerosis 6 | 333
pediatric high grade glioma 6 | 1,064
Abortion, Spontaneous 5 | 109
Arthritis 5 | 290
Crohn's disease 5 | 321
Depressive disorder 5 | 409
Epilepsy 5 | 792
Major Depressive Disorder 5 | 301
Mammary Neoplasms 5 | 425
Prostatic Neoplasms 5 | 495
Spontaneous abortion 5 | 113
Systemic lupus erythematosus 5 | 194
Type 2 diabetes mellitus 5 | 272
Unipolar Depression 5 | 250
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
mucosa-associated lymphoid tissue lymphoma 5 | 484
progressive supranuclear palsy 5 | 676

Tissue

Blood and immune system 73 | 16,909
Endocrine System 73 | 18,159
Female tissues 73 | 17,400
Digestive Tract 72 | 17,369
Liver and Pancreas 72 | 16,750
Respiratory system 72 | 16,393
Skin and soft tissues 72 | 17,230
Urinary Tract 72 | 16,678
Male tissues 71 | 17,142
Nervous System 71 | 16,725
Cardiovascular System 66 | 15,192

Target Family

Non-IDG 55 | 12,091
Enzyme 6 | 4,145
Kinase 5 | 634
Transporter 5 | 473
GPCR 3 | 408

GO Function

virus receptor activity 74 | 74
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Sodium/bile acid cotransporter SLC10A1 Tchem Transporter -2.69150 476.1 163
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Claudin-1 CLDN1 Tbio Non-IDG -2.07626 126.7 593
Aminopeptidase N ANPEP Tchem Enzyme -3.28127 1843.4 1222
Niemann-Pick C1 protein NPC1 Tbio Non-IDG -2.71962 551.3 284
Heat shock 70 kDa protein 1A HSPA1B Tchem Non-IDG -3.10995 0.00000 1174
Heat shock 70 kDa protein 1B HSPA1B Tbio Non-IDG -1.61862 0.00000 60
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677
Cadherin-related family member 3 CDHR3 Tdark Non-IDG -1.12856 13.9 46