Development Level

Tbio 6 | 11,445

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

diabetes mellitus 3 | 1,728
Carcinoma 2 | 11,493
Multiple myeloma 2 | 1,332
Waldenstrons macroglobulinemia 2 | 765
atypical teratoid / rhabdoid tumor 2 | 5,112
medulloblastoma, large-cell 2 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Adult onset 1 | 82
Aggressive Periodontitis 1 | 12
Alzheimer's disease 1 | 658
Amyotrophic Lateral Sclerosis, Guam Form 1 | 2
Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex 1 1 | 2
Anxiety 1 | 136
Anxiety disease 1 | 113
Autosomal recessive predisposition 1 | 1,442
Blepharospasm 1 | 13
Bradykinesia 1 | 34
Brain disease 1 | 96
Bubonic plague 1 | 1
Cancer 1 | 2,499
Carcinoma, Hepatocellular 1 | 228
Celiac disease 1 | 116
Chromosomal Instability 1 | 8
Chromosome 19q13.11 deletion syndrome 1 | 2
Crohn's disease 1 | 321
Enterocolitis, Necrotizing 1 | 17
Eumycotic mycetoma 1 | 3
Hereditary spherocytosis type 3 1 | 14
Liver carcinoma 1 | 240
Melanoma 1 | 711
Multiple system atrophy 1 | 29
Muscle Rigidity 1 | 49
Necrotizing Enterocolitis 1 | 17
Neurodegenerative disease 1 | 414
Osteoporosis 1 | 363
PARKINSON DISEASE 19, JUVENILE-ONSET 1 | 10
PARKINSON DISEASE 7, AUTOSOMAL RECESSIVE EARLY-ONSET 1 | 1
Parkinson Disease 1 | 64
Parkinson disease 7 1 | 1
Parkinson's disease 1 | 392
Parkinsonian Disorders 1 | 56
Pick disease 1 | 1,894
Psychotic episodes 1 | 3
Resting Tremor 1 | 9
Reticulocytosis 1 | 20
Rheumatoid arthritis 1 | 1,191
Slow progression 1 | 89
Static Tremor 1 | 21
Townes-Brocks syndrome 1 | 15
Toxic encephalopathy 1 | 141
Type 1 diabetes mellitus 1 | 109
Vitiligo 1 | 73
Xeroderma pigmentosum group C 1 | 5
Young onset Parkinson disease 1 | 10
chronic rhinosinusitis 1 | 512
cystic fibrosis 1 | 1,696
lung cancer 1 | 4,740
medulloblastoma 1 | 720
non primary Sjogren syndrome sicca 1 | 891
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
posterior fossa group B ependymoma 1 | 416
sonic hedgehog group medulloblastoma 1 | 467
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Enzyme 4 | 4,145
Non-IDG 2 | 12,091

GO Function

ubiquitin-like protein conjuga... 6 | 6
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.19489 157.7 218
Protein/nucleic acid deglycase DJ-1 PARK7 Tbio Enzyme -2.89261 835.5 625
E3 ubiquitin-protein ligase RNF5 RNF5 Tbio Enzyme -1.20054 15.1 166
E3 ubiquitin-protein ligase E3D UBE3D Tbio Enzyme -0.26587 1.59 7
SUMO-activating enzyme subunit 2 UBA2 Tbio Non-IDG -1.47530 27.8 259
E3 ubiquitin-protein ligase RNF185 RNF185 Tbio Enzyme -0.43136 2.34 111