Development Level

Tbio 2 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

increased basophil cell number 1 | 7
increased eosinophil cell numb... 1 | 11
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32

Disease

Arthritis 3 | 290
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
Liver disease 3 | 237
glioblastoma 3 | 5,792
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
ovarian cancer 3 | 8,520
subependymal giant cell astrocytoma 3 | 2,287
Abdominal Pain 2 | 98
Arthralgia 2 | 90
Autoimmune Diseases 2 | 67
Behcet's syndrome 2 | 50
Breast cancer 2 | 3,578
C-reactive protein increased 2 | 15
Carcinoma 2 | 11,493
Depressive disorder 2 | 409
Diabetes Mellitus, Experimental 2 | 108
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
ESR raised 2 | 20
Elevated C-reactive protein level 2 | 15
Fever 2 | 138
Gaucher disease type 3 2 | 67
Human immunodeficiency virus infectious disease 2 | 138
Hypersensitivity reaction type II disease 2 | 253
Kidney disease 2 | 430
Lung Neoplasms 2 | 232
Lung disease 2 | 142
Mental Depression 2 | 333
Multiple Sclerosis 2 | 540
Myalgia 2 | 54
Orchitis 2 | 28
Schizophrenia 2 | 1,160
Splenomegaly 2 | 190
Vascular disease 2 | 319
colon cancer 2 | 1,478
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
Acne 1 | 52
Acute Lung Injury 1 | 22
Amyloidosis 1 | 67
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Anorexia 1 | 43
Anti-nuclear factor positive 1 | 18
Aphthous stomatitis 1 | 16
Apraxias 1 | 27
Autoimmune hemolytic anemia 1 | 31
Behcet Syndrome 1 | 21
Biliary cirrhosis 1 | 45
Cellulitis of periorbital region 1 | 13
Confusion 1 | 21
Conjunctivitis 1 | 53
Diffuse large B-cell lymphoma 1 | 39
Edema 1 | 81
Erythema 1 | 58
Exanthem 1 | 37
Gastrointestinal Hemorrhage 1 | 52
Hemiparesis 1 | 34
Hepatocellular Adenoma 1 | 10
Hepatolenticular Degeneration 1 | 24
Increased IgM levels 1 | 16
Iridocyclitis 1 | 19
Iron deficiency anemia 1 | 12
Joint swelling 1 | 26
Juvenile rheumatoid arthritis 1 | 111
Juvenile rheumatoid factor-negative polyarthritis 1 | 9
Liver Cirrhosis, Biliary 1 | 33
Lung Injury 1 | 20
Lymphoma, Large B-Cell, Diffuse 1 | 34
Lymphoproliferative syndrome 1 | 58
Malaria, Falciparum 1 | 3
Malocclusion 1 | 57
Muscular stiffness 1 | 12
Myasthenia gravis 1 | 23
Nephritis 1 | 51
Nephrotic Syndrome 1 | 78
Oligoarticular juvenile arthritis 1 | 9
Pancreatitis 1 | 123
Papule 1 | 43
Pauciarticular juvenile rheumatoid arthritis 1 | 9
Pericarditis 1 | 13
Periorbital edema 1 | 13
Periorbital swelling 1 | 13
Platelet antibody positive 1 | 4
Polyarthritis 1 | 11
Premature canities 1 | 24
Primary immunodeficiency disease 1 | 54
Recurrent aphthous ulcer 1 | 14
Sparse scalp hair 1 | 42
Subcutaneous nodule 1 | 53
Ventricular Dysfunction, Left 1 | 22
hypopigmented skin patch 1 | 59

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Non-IDG 3 | 12,091

GO Function

tumor necrosis factor binding 3 | 3
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-2-macroglobulin A2M Tbio Non-IDG -2.96073 801.9 642
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.32299 2090.2 2060
Tumor necrosis factor receptor superfamily member 1A TNFRSF1A Tchem Non-IDG -3.31515 1897.3 1051