Development Level

Tbio 36 | 11,651
Tchem 5 | 1,388
Tdark 4 | 6,593
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal behavior 3 | 298
abnormal bone structure 3 | 187
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
abnormal cranium morphology 2 | 36
abnormal head morphology 2 | 10
abnormal retinal blood vessel ... 2 | 26
abnormal sleep behavior 2 | 70
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
preweaning lethality, incomple... 2 | 499
vertebral fusion 2 | 23
abnormal QT variability 1 | 10
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal external female genit... 1 | 1
abnormal external male genital... 1 | 1
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal retinal vasculature m... 1 | 27
abnormal tail morphology 1 | 25
abnormal tail movements 1 | 12
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
convulsive seizures 1 | 13
decreased anxiety-related resp... 1 | 12
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased body temperature 1 | 9
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mydriasis 1 | 6
persistence of hyaloid vascula... 1 | 33

Disease

Carcinoma 31 | 11,493
ovarian cancer 30 | 8,520
glioblastoma 21 | 5,792
medulloblastoma, large-cell 20 | 6,241
lung cancer 19 | 4,740
psoriasis 19 | 6,694
osteosarcoma 18 | 7,950
group 3 medulloblastoma 17 | 4,104
atypical teratoid / rhabdoid tumor 16 | 5,112
ependymoma 16 | 4,679
Kidney cancer 14 | 2,613
adult high grade glioma 12 | 3,801
astrocytic glioma 12 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
malignant mesothelioma 12 | 3,232
Breast cancer 11 | 3,578
lung adenocarcinoma 11 | 2,716
oligodendroglioma 11 | 2,850
Astrocytoma, Pilocytic 10 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
colon cancer 9 | 1,478
non-small cell lung cancer 9 | 2,890
Pick disease 8 | 1,894
invasive ductal carcinoma 8 | 2,951
lung carcinoma 8 | 2,843
primitive neuroectodermal tumor 8 | 3,035
Cancer 7 | 2,499
ductal carcinoma in situ 7 | 1,745
pancreatic cancer 7 | 2,398
Intellectual disability 6 | 1,016
acute myeloid leukemia 6 | 783
breast carcinoma 6 | 1,638
diabetes mellitus 6 | 1,728
nasopharyngeal carcinoma 6 | 1,058
Neurodegenerative disease 5 | 414
adrenocortical carcinoma 5 | 1,428
juvenile dermatomyositis 5 | 1,187
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Alzheimer's disease 4 | 658
Atopic dermatitis 4 | 952
Autosomal recessive predisposition 4 | 1,442
Breast Neoplasms 4 | 445
Liver cancer 4 | 604
Mammary Neoplasms 4 | 425
Multiple myeloma 4 | 1,332
Nerve Degeneration 4 | 121
Parkinson's disease 4 | 392
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
pituitary cancer 4 | 1,972
progressive supranuclear palsy 4 | 676
Crohn's disease 3 | 321
Dementia 3 | 175
Depressive disorder 3 | 409
Down syndrome 3 | 499
Endometriosis 3 | 540
Gaucher disease type 1 3 | 180
Microcephaly 3 | 166
Multiple system atrophy 3 | 29
Ovarian Neoplasms 3 | 102
Parkinsonian Disorders 3 | 56
Prostatic Neoplasms 3 | 495
Toxic encephalopathy 3 | 141
cutaneous lupus erythematosus 3 | 1,057
gastric cancer 3 | 459
group 4 medulloblastoma 3 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
sonic hedgehog group medulloblastoma 3 | 467
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
Abnormality of metabolism/homeostasis 2 | 134
Adult T-Cell Lymphoma/Leukemia 2 | 30
Adult onset 2 | 82
Bipolar Disorder 2 | 666
Bradykinesia 2 | 34
Colonic Neoplasms 2 | 142
Epilepsy 2 | 792
Leukemia-Lymphoma, Adult T-Cell 2 | 30
Lissencephaly 2 | 69
Lung Neoplasms 2 | 232
Melanoma 2 | 711
Mental Depression 2 | 333
Parkinson Disease 2 | 64
Respiratory Failure 2 | 104
Stomach Neoplasms 2 | 300
Tremor 2 | 113
astrocytoma 2 | 1,146
chronic rhinosinusitis 2 | 512
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
pancreatic carcinoma 2 | 562
posterior fossa group A ependymoma 2 | 468
posterior fossa group B ependymoma 2 | 416

Tissue

Endocrine System 46 | 18,159
Female tissues 46 | 17,400
Male tissues 46 | 17,142
Nervous System 46 | 16,725
Respiratory system 46 | 16,393
Skin and soft tissues 46 | 17,230
Digestive Tract 45 | 17,369
Urinary Tract 45 | 16,678
Liver and Pancreas 44 | 16,750
Blood and immune system 43 | 16,909
Cardiovascular System 40 | 15,192

Target Family

Non-IDG 30 | 12,091
Enzyme 11 | 4,145
Epigenetic 2 | 242
Kinase 2 | 634
Transcription Factor 1 | 1,400

GO Function

tubulin binding 46 | 46
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RBPJ-interacting and tubulin-associated protein 1 RITA1 Tbio Non-IDG -0.85891 6.79 61
Glycosylphosphatidylinositol anchor attachment 1 protein GPAA1 Tbio Non-IDG -1.52498 33.6 113
Stathmin-3 STMN3 Tbio Non-IDG -1.14217 14.1 144
Intraflagellar transport protein 81 homolog IFT81 Tbio Non-IDG -2.04582 108.8 104
Stathmin STMN1 Tbio Non-IDG -2.90296 824.2 1052
Stathmin-2 STMN2 Tbio Non-IDG -1.97011 93.3 326
Breast cancer type 1 susceptibility protein BRCA1 Tchem Non-IDG -3.76784 6081.3 1542
Stathmin-4 STMN4 Tbio Non-IDG -2.06131 113.1 106
Tubulin polymerization-promoting protein family member 2 TPPP2 Tbio Non-IDG -0.38917 2.03 29
Cytosolic carboxypeptidase 1 AGTPBP1 Tbio Enzyme -1.64119 47.2 230