Development Level

Tbio 7 | 11,445
Tchem 5 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

IMPC Phenotype

abnormal heart morphology 1 | 162
decreased vertical activity 1 | 208
enlarged heart 1 | 210
increased heart weight 1 | 62
male infertility 1 | 123
premature death 1 | 5
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 11 | 11,493
psoriasis 9 | 6,694
diabetes mellitus 8 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
ovarian cancer 7 | 8,520
Obesity 6 | 678
lung cancer 6 | 4,740
Autosomal recessive predisposition 5 | 1,442
glioblastoma 5 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
malignant mesothelioma 5 | 3,232
Lipid metabolism disorder 4 | 114
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
pancreatic cancer 4 | 2,398
Atherosclerosis 3 | 291
Atopic dermatitis 3 | 952
Breast cancer 3 | 3,578
Ichthyosis 3 | 56
Pancreatitis 3 | 123
ductal carcinoma in situ 3 | 1,745
fibroadenoma 3 | 559
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
Amyotrophic lateral sclerosis 2 | 451
Astrocytoma, Pilocytic 2 | 3,081
Cardiovascular system disease 2 | 246
Cholesterol ester storage disease 2 | 6
Coronary artery disease 2 | 268
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Dyslipidemias 2 | 27
Ectropion 2 | 38
Eruptive xanthoma 2 | 3
Fatty liver disease 2 | 103
Hepatitis C 2 | 94
Hypercholesterolemia, Familial 2 | 23
Hyperlipidemia 2 | 43
Hyperlipidemias 2 | 17
Hyperlipoproteinemia Type II 2 | 12
Hypertriglyceridemia result 2 | 37
Insulin Resistance 2 | 72
Liver Cirrhosis, Experimental 2 | 769
Metabolic syndrome X 2 | 52
Neutral lipid storage disease 2 | 12
Polycystic ovary syndrome 2 | 360
Steatorrhea 2 | 34
Type 2 diabetes mellitus 2 | 272
Vascular disease 2 | 319
active Crohn's disease 2 | 922
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
combined hyperlipidemia 2 | 3
cutaneous lupus erythematosus 2 | 1,057
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Abdominal pain, episodic 1 | 9
Abnormality of lipid metabolism 1 | 9
Abnormality of the labia majora 1 | 2
Acanthosis Nigricans 1 | 27
Age related macular degeneration 1 | 72
Anemia, Megaloblastic 1 | 16
Asphyxiating thoracic dystrophy 1 | 44
Choledocholithiasis 1 | 11
Chronic diarrhea 1 | 29
Congenital ichthyosiform erythroderma 1 | 28
Deglutition Disorders 1 | 132
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Exocrine pancreatic insufficiency 1 | 32
Familial hyperlipidemia 1 | 6
Familial partial lipodystrophy 1 | 12
Heart Diseases 1 | 43
Hepatosplenomegaly 1 | 22
Hyperglycemia 1 | 137
Hyperlipoproteinemias 1 | 5
Hypertriglyceridemia 1 | 17
Lipodystrophy 1 | 40
Macular degeneration 1 | 65
Maturity onset diabetes mellitus in young 1 | 11
Methemoglobinemia 1 | 17
Nausea 1 | 20
Neurodegeneration with brain iron accumulation 1 | 20
Obesity, Abdominal 1 | 24
Oligomenorrhea 1 | 16
Pancreatic Insufficiency 1 | 13
Pancreatitis, Chronic 1 | 9
Primary cutaneous amyloidosis 1 | 29
Serum cholesterol raised 1 | 22
Spastic Ataxia 1 | 18
Steatohepatitis 1 | 44
Systemic primary carnitine deficiency disease 1 | 15
chronic kidney disease 1 | 90
intermittent abdominal pain 1 | 9
maturity-onset diabetes of the young 1 | 32

Tissue

Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Blood and immune system 14 | 16,909
Skin and soft tissues 14 | 17,230
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Urinary Tract 12 | 16,678
Cardiovascular System 11 | 15,192

Target Family

Enzyme 16 | 4,145

GO Function

triglyceride lipase activity 16 | 16
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pancreatic lipase-related protein 3 PNLIPRP3 Tdark Enzyme 0.30 0.50 88
Arylacetamide deacetylase AADAC Tbio Enzyme -1.33418 25.6 116
Hormone-sensitive lipase LIPE Tchem Enzyme -2.75527 464.8 340
Bile salt-activated lipase CEL Tchem Enzyme -2.57254 373.8 0
Lipoprotein lipase LPL Tchem Enzyme -3.09646 876.3 338
Patatin-like phospholipase domain-containing protein 1 PNPLA1 Tbio Enzyme -1.33674 19.5 102
Patatin-like phospholipase domain-containing protein 4 PNPLA4 Tbio Enzyme -0.89406 6.90 80
Phospholipase DDHD2 DDHD2 Tbio Enzyme -1.23833 16.6 49
Hepatic triacylglycerol lipase LIPC Tchem Enzyme -2.56840 389.0 258
Patatin-like phospholipase domain-containing protein 2 PNPLA2 Tchem Enzyme -2.68285 486.4 398