Development Level

Tbio 90 | 11,445
Tdark 24 | 6,588
Tchem 16 | 1,598
Tclin 4 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 4 | 499
abnormal heart morphology 3 | 162
decreased bone mineral density 3 | 126
enlarged heart 3 | 210
increased circulating alkaline... 3 | 122
abnormal epididymis morphology 2 | 42
abnormal lung morphology 2 | 26
abnormal seminal vesicle morph... 2 | 114
cardiovascular system phenotyp... 2 | 36
decreased leukocyte cell numbe... 2 | 73
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
enlarged epididymis 2 | 31
increased circulating HDL chol... 2 | 80
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased or absent threshold ... 2 | 101
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal heart shape 1 | 5
abnormal lens morphology 1 | 81
abnormal ovary morphology 1 | 7
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased cardiac muscle contr... 1 | 11
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased pulmonary respirator... 1 | 5
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged ovary 1 | 2
enlarged seminal vesicle 1 | 10
enlarged spleen 1 | 41
hydrometra 1 | 53
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased heart rate 1 | 23
increased heart rate variabili... 1 | 7
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24
vertebral fusion 1 | 23

Disease

Carcinoma 80 | 11,493
ovarian cancer 60 | 8,520
psoriasis 52 | 6,694
osteosarcoma 43 | 7,950
medulloblastoma, large-cell 41 | 6,241
lung cancer 37 | 4,740
glioblastoma 35 | 5,792
ependymoma 34 | 4,679
atypical teratoid / rhabdoid tumor 32 | 5,112
group 3 medulloblastoma 32 | 4,104
Breast cancer 24 | 3,578
adult high grade glioma 23 | 3,801
lung adenocarcinoma 23 | 2,716
malignant mesothelioma 23 | 3,232
oligodendroglioma 23 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,962
Astrocytoma, Pilocytic 22 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
primitive neuroectodermal tumor 22 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
Schizophrenia 19 | 1,160
astrocytic glioma 19 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
Cancer 17 | 2,499
Multiple myeloma 17 | 1,332
invasive ductal carcinoma 17 | 2,951
lung carcinoma 17 | 2,843
non-small cell lung cancer 17 | 2,890
Autosomal recessive predisposition 16 | 1,442
Pick disease 16 | 1,894
Kidney cancer 15 | 2,613
Rheumatoid arthritis 15 | 1,191
pancreatic cancer 15 | 2,398
Epilepsy 12 | 792
interstitial cystitis 12 | 2,312
pituitary cancer 12 | 1,972
subependymal giant cell astrocytoma 12 | 2,287
Liver Cirrhosis, Experimental 11 | 769
active ulcerative colitis 11 | 764
tuberculosis 11 | 2,010
ulcerative colitis 11 | 1,819
adrenocortical carcinoma 10 | 1,428
astrocytoma 10 | 1,146
breast carcinoma 10 | 1,638
ductal carcinoma in situ 10 | 1,745
Alzheimer's disease 9 | 658
active Crohn's disease 9 | 922
cutaneous lupus erythematosus 9 | 1,057
diabetes mellitus 9 | 1,728
pediatric high grade glioma 9 | 1,064
Atopic dermatitis 8 | 952
Bipolar Disorder 8 | 666
Colorectal Neoplasms 8 | 243
Kidney disease 8 | 430
Obesity 8 | 678
group 4 medulloblastoma 8 | 1,855
Melanoma 7 | 711
Seizures 7 | 596
acute quadriplegic myopathy 7 | 1,158
cystic fibrosis 7 | 1,696
Liver carcinoma 6 | 240
Low Vision 6 | 174
Skin cancer 6 | 469
Visual Impairment 6 | 174
Waldenstrons macroglobulinemia 6 | 765
acute myeloid leukemia 6 | 783
colon cancer 6 | 1,478
esophageal adenocarcinoma 6 | 737
primary pancreatic ductal adenocarcinoma 6 | 1,109
Blind Vision 5 | 111
Blindness, Legal 5 | 110
Breast Neoplasms 5 | 445
Chemical and Drug Induced Liver Injury 5 | 195
Cholestasis 5 | 155
Dementia 5 | 175
Disease Progression 5 | 136
Endometriosis 5 | 540
Failure to gain weight 5 | 365
Glaucoma 5 | 239
Hypertension 5 | 396
Hypertensive disease 5 | 292
Mammary Neoplasms 5 | 425
Mammary Neoplasms, Experimental 5 | 154
Osteoporosis 5 | 363
Parkinson's disease 5 | 392
Pediatric failure to thrive 5 | 365
dermatomyositis 5 | 966
hepatocellular carcinoma 5 | 547
juvenile dermatomyositis 5 | 1,187
mucosa-associated lymphoid tissue lymphoma 5 | 484
non primary Sjogren syndrome sicca 5 | 891
pancreatic carcinoma 5 | 562
progressive supranuclear palsy 5 | 676
Broad flat nasal bridge 4 | 236
Hepatomegaly 4 | 285
chronic rhinosinusitis 4 | 512
nasopharyngeal carcinoma 4 | 1,058
nephrosclerosis 4 | 333
primary Sjogren syndrome 4 | 735
spina bifida 4 | 1,074

Tissue

Male tissues 127 | 17,142
Digestive Tract 126 | 17,369
Endocrine System 123 | 18,159
Female tissues 123 | 17,400
Nervous System 122 | 16,725
Skin and soft tissues 120 | 17,230
Blood and immune system 117 | 16,909
Liver and Pancreas 117 | 16,750
Urinary Tract 116 | 16,678
Respiratory system 115 | 16,393
Cardiovascular System 105 | 15,192

Target Family

Non-IDG 77 | 12,091
Transporter 30 | 473
Enzyme 24 | 4,145
Ion Channel 3 | 344

GO Function

transporter activity 134 | 134
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-tocopherol transfer protein-like TTPAL Tdark Non-IDG 0.71 0.12 52
Calcium-activated chloride channel regulator family member 3 CLCA3P Tdark Ion Channel 0.00000 0
Feline leukemia virus subgroup C receptor-related protein 1 FLVCR1 Tbio Non-IDG -1.54460 33.8 139
Solute carrier family 13 member 4 SLC13A4 Tbio Transporter -1.55886 37.5 50
Retinoid-binding protein 7 RBP7 Tbio Non-IDG -0.86335 6.26 89
Mitochondrial import inner membrane translocase subunit Tim9 TIMM9 Tbio Enzyme -1.31703 21.3 72
Epididymal-specific lipocalin-9 LCN9 Tdark Non-IDG -0.47470 3.06 61
Copine-1 CPNE1 Tbio Non-IDG -1.04880 11.6 151
Organic solute transporter subunit beta SLC51B Tbio Transporter -1.41741 22.6 42
ATP-binding cassette sub-family A member 3 ABCA3 Tbio Transporter -2.25972 187.7 32