Development Level

Tdark 97 | 7,003
Tbio 73 | 10,625
Tchem 16 | 1,890
Tclin 15 | 602

IMPC Term

increased circulating alkaline... 4 | 119
decreased lean body mass 3 | 195
preweaning lethality, incomple... 3 | 260
tremors 3 | 34
abnormal behavior 2 | 226
abnormal bone structure 2 | 131
abnormal gait 2 | 51
decreased bone mineral content 2 | 157
decreased circulating alkaline... 2 | 41
decreased leukocyte cell numbe... 2 | 54
decreased rib number 2 | 59
enlarged heart 2 | 111
enlarged spleen 2 | 26
hypoactivity 2 | 89
increased circulating choleste... 2 | 53
increased mean corpuscular vol... 2 | 91
lethargy 2 | 5
preweaning lethality, complete... 2 | 633
abnormal digit morphology 1 | 13
abnormal eye anterior chamber ... 1 | 3
abnormal heart left ventricle ... 1 | 20
abnormal locomotor activation 1 | 26
abnormal seminal vesicle morph... 1 | 47
abnormal skin morphology 1 | 23
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal vibrissa morphology 1 | 17
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased pulmonary respirator... 1 | 4
decreased spleen weight 1 | 13
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged liver 1 | 3
enlarged stomach 1 | 2
impaired glucose tolerance 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating creatini... 1 | 29
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 93
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
prenatal lethality prior to he... 1 | 64
short snout 1 | 4
short tibia 1 | 82
shortened head 1 | 2
small seminal vesicle 1 | 6
small superior vagus ganglion 1 | 20
small thymus 1 | 11
thrombocytopenia 1 | 46

Disease

osteosarcoma 69 | 7,933
psoriasis 58 | 6,685
lung cancer 47 | 4,473
lung carcinoma 47 | 2,844
Cancer 46 | 2,346
ovarian cancer 43 | 8,492
interstitial cystitis 40 | 2,299
glioblastoma 36 | 5,572
cutaneous lupus erythematosus 34 | 1,056
lung adenocarcinoma 33 | 2,714
diabetes mellitus 32 | 1,663
invasive ductal carcinoma 32 | 2,950
Carcinoma 31 | 2,147
medulloblastoma, large-cell 30 | 6,234
non-small cell lung cancer 29 | 2,798
ulcerative colitis 27 | 2,087
pilocytic astrocytoma 26 | 3,086
Breast cancer 25 | 3,099
pancreatic cancer 25 | 2,300
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,289
tuberculosis 24 | 1,563
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,988
atypical teratoid / rhabdoid tumor 22 | 4,369
malignant mesothelioma 22 | 3,163
subependymal giant cell astrocytoma 22 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,956
Rheumatoid Arthritis 20 | 1,171
pituitary cancer 20 | 1,972
pediatric high grade glioma 18 | 2,712
adult high grade glioma 17 | 2,148
cystic fibrosis 17 | 1,670
breast carcinoma 16 | 1,614
ductal carcinoma in situ 16 | 1,745
primary Sjogren syndrome 16 | 789
group 3 medulloblastoma 15 | 2,254
Asthma 14 | 349
Obesity 14 | 616
colon cancer 13 | 1,475
adrenocortical carcinoma 12 | 1,427
nasopharyngeal carcinoma 12 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
primitive neuroectodermal tumor 12 | 3,031
Inflammatory bowel disease 11 | 142
oligodendroglioma 11 | 2,849
Arthritis 10 | 248
Atherosclerosis 10 | 275
Human immunodeficiency virus infectious disease 10 | 129
Pick disease 10 | 1,893
Prostatic Neoplasms 10 | 471
ependymoma 10 | 2,514
gastric carcinoma 10 | 832
group 4 medulloblastoma 10 | 1,875
Allergic hypersensitivity disease 9 | 123
Hypersensitivity reaction type II disease 9 | 235
IGA Glomerulonephritis 9 | 454
Influenza 9 | 142
Kidney disease 9 | 397
Multiple Sclerosis 9 | 498
medulloblastoma 9 | 1,524
non-small cell lung carcinoma 9 | 413
posterior fossa group A ependymoma 9 | 1,511
posterior fossa group B ependymoma 9 | 1,530
Dermatitis 8 | 141
Peripheral Neuropathy 8 | 303
Thrombocytopenia 8 | 105
aldosterone-producing adenoma 8 | 664
fibroadenoma 8 | 557
pancreatic carcinoma 8 | 567
Atopic dermatitis 7 | 944
Endometriosis 7 | 535
Inflammation 7 | 109
Lupus erythematosus 7 | 80
Pneumonia 7 | 133
astrocytic glioma 7 | 2,241
periodontitis 7 | 269
primary pancreatic ductal adenocarcinoma 7 | 1,271
sarcoidosis 7 | 368
systemic lupus erythematosus 7 | 172
Alzheimer's disease 6 | 644
Coronary artery disease 6 | 240
Duchenne muscular dystrophy 6 | 602
Heart disease 6 | 279
Hypertension 6 | 293
Liver disease 6 | 219
Malaria 6 | 140
Mammary Neoplasms 6 | 410
active Crohn's disease 6 | 918
atypical teratoid/rhabdoid tumor 6 | 1,095
head and neck cancer 6 | 270
head and neck cancer and chronic obstructive pulmonary disease 6 | 237
juvenile dermatomyositis 6 | 1,189
mucosa-associated lymphoid tissue lymphoma 6 | 480
sonic hedgehog group medulloblastoma 6 | 1,482
Down syndrome 5 | 548
Schizophrenia 5 | 503
Waldenstrons macroglobulinemia 5 | 765
acute quadriplegic myopathy 5 | 1,157
astrocytoma 5 | 1,493
hepatocellular carcinoma 5 | 550
urothelial carcinoma 5 | 318

Tissue

Female tissues 178 | 18,647
Urinary Tract 163 | 18,444
Digestive Tract 149 | 18,473
Nervous System 147 | 18,561
Endocrine System 145 | 18,512
Skin and soft tissues 132 | 18,115
Blood and immune system 128 | 17,995
Liver and Pancreas 125 | 18,136
Cardiovascular System 122 | 17,958
Male tissues 121 | 17,969
Respiratory system 115 | 17,484

Target Family

Non-IDG 91 | 11,969
oGPCR 90 | 421
GPCR 9 | 408
Ion Channel 4 | 341
Kinase 4 | 634
Enzyme 2 | 4,146
Transporter 1 | 473

GO Function

transmembrane signaling recept... 201 | 201
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C Tbio Non-IDG -2.59865 595.2 0
Platelet glycoprotein VI GP6 Tbio Non-IDG -2.71040 549.1 166
Leucine-rich repeat-containing G-protein coupled receptor 6 LGR6 Tbio GPCR -1.31264 22.5 138
Solute carrier family 22 member 17 SLC22A17 Tbio Transporter -1.29083 14.9 133
Killer cell immunoglobulin-like receptor 2DL4 KIR2DL4 Tbio Non-IDG -1.86245 74.3 149
Toll-like receptor 10 TLR10 Tbio Non-IDG -1.75724 56.1 295
Leucine-rich repeat-containing G-protein coupled receptor 4 LGR4 Tbio GPCR -1.68497 61.4 199
Neurexin-3-beta NRXN3 Tbio Non-IDG -1.29937 33.0 142
Killer cell immunoglobulin-like receptor 2DS1 KIR2DS1 Tdark Non-IDG 0.00000 0
Olfactory receptor 2A25 OR2A25 Tdark oGPCR 0.00000 38