Development Level

Tdark 97 | 7,003
Tbio 73 | 10,625
Tchem 16 | 1,890
Tclin 15 | 602

IMPC Term

increased circulating alkaline... 4 | 119
decreased lean body mass 3 | 195
preweaning lethality, incomple... 3 | 260
tremors 3 | 34
abnormal behavior 2 | 226
abnormal bone structure 2 | 131
abnormal gait 2 | 51
decreased bone mineral content 2 | 157
decreased circulating alkaline... 2 | 41
decreased leukocyte cell numbe... 2 | 54
decreased rib number 2 | 59
enlarged heart 2 | 111
enlarged spleen 2 | 26
hypoactivity 2 | 89
increased circulating choleste... 2 | 53
increased mean corpuscular vol... 2 | 91
lethargy 2 | 5
preweaning lethality, complete... 2 | 633
abnormal digit morphology 1 | 13
abnormal eye anterior chamber ... 1 | 3
abnormal heart left ventricle ... 1 | 20
abnormal locomotor activation 1 | 26
abnormal seminal vesicle morph... 1 | 47
abnormal skin morphology 1 | 23
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal vibrissa morphology 1 | 17
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased pulmonary respirator... 1 | 4
decreased spleen weight 1 | 13
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged liver 1 | 3
enlarged stomach 1 | 2
impaired glucose tolerance 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating creatini... 1 | 29
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 93
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
prenatal lethality prior to he... 1 | 64
short snout 1 | 4
short tibia 1 | 82
shortened head 1 | 2
small seminal vesicle 1 | 6
small superior vagus ganglion 1 | 20
small thymus 1 | 11
thrombocytopenia 1 | 46

Disease

osteosarcoma 69 | 7,933
psoriasis 58 | 6,685
lung cancer 47 | 4,466
lung carcinoma 47 | 2,844
Cancer 46 | 2,346
ovarian cancer 42 | 8,484
interstitial cystitis 40 | 2,299
glioblastoma 36 | 5,572
cutaneous lupus erythematosus 34 | 1,056
lung adenocarcinoma 33 | 2,713
diabetes mellitus 32 | 1,663
invasive ductal carcinoma 32 | 2,950
Carcinoma 31 | 2,147
medulloblastoma, large-cell 30 | 6,234
non-small cell lung cancer 29 | 2,798
ulcerative colitis 27 | 2,087
pilocytic astrocytoma 26 | 3,086
Breast cancer 25 | 3,094
pancreatic cancer 25 | 2,300
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,289
tuberculosis 24 | 1,557
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,988
atypical teratoid / rhabdoid tumor 22 | 4,369
malignant mesothelioma 22 | 3,162
subependymal giant cell astrocytoma 22 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,956
Rheumatoid Arthritis 20 | 1,160
pituitary cancer 20 | 1,972
pediatric high grade glioma 18 | 2,712
adult high grade glioma 17 | 2,148
cystic fibrosis 17 | 1,665
breast carcinoma 16 | 1,614
ductal carcinoma in situ 16 | 1,745
primary Sjogren syndrome 16 | 789
group 3 medulloblastoma 15 | 2,254
Asthma 14 | 349
Obesity 14 | 616
colon cancer 13 | 1,475
adrenocortical carcinoma 12 | 1,427
nasopharyngeal carcinoma 12 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
primitive neuroectodermal tumor 12 | 3,031
Inflammatory bowel disease 11 | 142
oligodendroglioma 11 | 2,849
Arthritis 10 | 248
Atherosclerosis 10 | 275
Human immunodeficiency virus infectious disease 10 | 92
Pick disease 10 | 1,893
Prostatic Neoplasms 10 | 471
ependymoma 10 | 2,514
gastric carcinoma 10 | 832
group 4 medulloblastoma 10 | 1,875
Allergic hypersensitivity disease 9 | 123
Hypersensitivity reaction type II disease 9 | 235
IGA Glomerulonephritis 9 | 454
Influenza 9 | 142
Kidney disease 9 | 396
Multiple Sclerosis 9 | 498
medulloblastoma 9 | 1,524
non-small cell lung carcinoma 9 | 413
posterior fossa group A ependymoma 9 | 1,511
posterior fossa group B ependymoma 9 | 1,530
Dermatitis 8 | 107
Peripheral Neuropathy 8 | 303
Thrombocytopenia 8 | 105
aldosterone-producing adenoma 8 | 664
fibroadenoma 8 | 557
pancreatic carcinoma 8 | 567
Atopic dermatitis 7 | 944
Endometriosis 7 | 535
Inflammation 7 | 109
Lupus erythematosus 7 | 80
Pneumonia 7 | 133
astrocytic glioma 7 | 2,241
periodontitis 7 | 269
primary pancreatic ductal adenocarcinoma 7 | 1,271
sarcoidosis 7 | 358
systemic lupus erythematosus 7 | 156
Alzheimer's disease 6 | 644
Coronary artery disease 6 | 240
Duchenne muscular dystrophy 6 | 602
Heart disease 6 | 279
Hypertension 6 | 287
Liver disease 6 | 219
Malaria 6 | 140
Mammary Neoplasms 6 | 410
active Crohn's disease 6 | 918
atypical teratoid/rhabdoid tumor 6 | 1,095
head and neck cancer 6 | 270
head and neck cancer and chronic obstructive pulmonary disease 6 | 237
juvenile dermatomyositis 6 | 1,189
mucosa-associated lymphoid tissue lymphoma 6 | 480
sonic hedgehog group medulloblastoma 6 | 1,482
Down syndrome 5 | 548
Schizophrenia 5 | 501
Waldenstrons macroglobulinemia 5 | 765
acute quadriplegic myopathy 5 | 1,157
astrocytoma 5 | 1,493
hepatocellular carcinoma 5 | 532
urothelial carcinoma 5 | 318

Tissue

Female tissues 178 | 18,647
Urinary Tract 163 | 18,444
Digestive Tract 149 | 18,473
Nervous System 147 | 18,561
Endocrine System 145 | 18,512
Skin and soft tissues 132 | 18,115
Blood and immune system 128 | 17,995
Liver and Pancreas 125 | 18,136
Cardiovascular System 122 | 17,958
Male tissues 121 | 17,969
Respiratory system 115 | 17,484

Target Family

Non-IDG 91 | 11,971
oGPCR 90 | 421
GPCR 9 | 406
Ion Channel 4 | 341
Kinase 4 | 634
Enzyme 2 | 4,146
Transporter 1 | 473

GO Function

transmembrane signaling recept... 201 | 201
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-cell receptor gamma-2 chain C region TRGC2 Tdark Non-IDG 0.00000 0
Killer cell lectin-like receptor subfamily B member 1 KLRB1 Tbio Non-IDG -2.39953 313.9 488
Interleukin-1 receptor type 1 IL1R1 Tclin Non-IDG -2.63413 362.9 482
Toll-like receptor 7 TLR7 Tclin Non-IDG -2.92878 974.2 670
NKG2-C type II integral membrane protein KLRC2 Tbio Non-IDG -1.86834 75.2 128
NKG2-A/NKG2-B type II integral membrane protein KLRC1 Tbio Non-IDG -2.40441 255.8 351
Olfactory receptor 4C6 OR4C6 Tdark oGPCR 0.47 0.31 37
Olfactory receptor 4S2 OR4S2 Tdark oGPCR 0.60 0.25 53
Olfactory receptor 6K6 OR6K6 Tdark oGPCR 0.00000 58
Olfactory receptor 4A5 OR4A5 Tdark oGPCR 0.00000 6