Development Level

Tbio 10 | 10,625
Tchem 7 | 1,890

IMPC Term

abnormal sleep behavior 1 | 63
hydrops fetalis 1 | 22
increased vertical activity 1 | 18
persistence of hyaloid vascula... 1 | 22

Disease

medulloblastoma, large-cell 12 | 6,234
ovarian cancer 12 | 8,484
Carcinoma 10 | 2,147
non-small cell lung cancer 10 | 2,798
osteosarcoma 10 | 7,933
interstitial cystitis 9 | 2,299
lung cancer 9 | 4,466
glioblastoma 8 | 5,572
atypical teratoid / rhabdoid tumor 7 | 4,369
ulcerative colitis 7 | 2,087
malignant mesothelioma 6 | 3,162
pituitary cancer 6 | 1,972
psoriasis 6 | 6,685
Breast cancer 5 | 3,094
group 4 medulloblastoma 5 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
lung adenocarcinoma 5 | 2,713
lung carcinoma 5 | 2,844
pediatric high grade glioma 5 | 2,712
pilocytic astrocytoma 5 | 3,086
subependymal giant cell astrocytoma 5 | 2,287
adult high grade glioma 4 | 2,148
astrocytic glioma 4 | 2,241
colon cancer 4 | 1,475
cystic fibrosis 4 | 1,665
group 3 medulloblastoma 4 | 2,254
invasive ductal carcinoma 4 | 2,950
oligodendroglioma 4 | 2,849
Cancer 3 | 2,346
Kidney disease 3 | 396
Melanoma 3 | 261
Pick disease 3 | 1,893
acute quadriplegic myopathy 3 | 1,157
adrenocortical carcinoma 3 | 1,427
aldosterone-producing adenoma 3 | 664
breast carcinoma 3 | 1,614
cutaneous lupus erythematosus 3 | 1,056
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 2,514
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 832
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
pancreatic cancer 3 | 2,300
posterior fossa group A ependymoma 3 | 1,511
primary Sjogren syndrome 3 | 789
tuberculosis 3 | 1,557
Chronic Lymphocytic Leukemia 2 | 242
Globe disease 2 | 57
Hyperkalemic periodic paralysis 2 | 10
IGA Glomerulonephritis 2 | 454
Multiple Sclerosis 2 | 498
Myopia 2 | 99
Stomach Neoplasms 2 | 282
Ureterocele 2 | 10
acute myeloid leukemia 2 | 780
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
dermatomyositis 2 | 933
diabetes mellitus 2 | 1,663
fibroadenoma 2 | 557
juvenile dermatomyositis 2 | 1,189
medulloblastoma 2 | 1,524
nasopharyngeal carcinoma 2 | 1,056
nephrosclerosis 2 | 329
posterior fossa group B ependymoma 2 | 1,530
primary pancreatic ductal adenocarcinoma 2 | 1,271
sonic hedgehog group medulloblastoma 2 | 1,482
Allergic hypersensitivity disease 1 | 123
Arthritis 1 | 248
Chronic obstructive pulmonary disease 1 | 146
Contact Dermatitis 1 | 80
Corneal disease 1 | 32
Diabetes Mellitus, Non-Insulin-Dependent 1 | 157
Disease Progression 1 | 125
Down syndrome 1 | 548
Epilepsy 1 | 346
Heart conduction disease 1 | 65
Heart disease 1 | 279
Helicobacter Infections 1 | 5
Hypersensitivity reaction type II disease 1 | 235
Inflammatory bowel disease 1 | 142
Inflammatory dermatosis 1 | 38
Lung disease 1 | 132
Mental depression 1 | 58
Myocardial Ischemia 1 | 169
Nonsyndromic deafness 1 | 121
Peripheral Neuropathy 1 | 303
Peripheral vascular disease 1 | 90
Vascular disease 1 | 281
Waldenstrons macroglobulinemia 1 | 765
active Crohn's disease 1 | 918
astrocytoma 1 | 1,493
atypical teratoid/rhabdoid tumor 1 | 1,095
cystic fibrosis and chronic rhinosinusitis 1 | 213
head and neck cancer 1 | 270
non-small cell lung carcinoma 1 | 413
progressive supranuclear palsy 1 | 674
severe Alzheimer's disease 1 | 49
tuberculosis and treatment for 3 months 1 | 327
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 17 | 17,995
Cardiovascular System 17 | 17,958
Digestive Tract 17 | 18,473
Endocrine System 17 | 18,512
Female tissues 17 | 18,647
Liver and Pancreas 17 | 18,136
Male tissues 17 | 17,969
Nervous System 17 | 18,561
Respiratory system 17 | 17,484
Skin and soft tissues 17 | 18,115
Urinary Tract 17 | 18,444

Target Family

Enzyme 17 | 4,146

GO Function

transmembrane receptor protein... 17 | 17
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

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