Development Level

Tbio 11 | 11,445
Tdark 4 | 6,588
Tchem 3 | 1,598

IMPC Phenotype

abnormal retina morphology 2 | 71
increased circulating free fat... 2 | 20
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal snout morphology 1 | 23
corneal opacity 1 | 32
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased total body fat amoun... 1 | 207
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
male infertility 1 | 123
vertebral transformation 1 | 12

Disease

Carcinoma 14 | 11,493
ependymoma 7 | 4,679
Cancer 6 | 2,499
lung cancer 6 | 4,740
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
glioblastoma 5 | 5,792
medulloblastoma, large-cell 5 | 6,241
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
oligodendroglioma 4 | 2,850
psoriasis 4 | 6,694
astrocytic glioma 3 | 2,597
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
non-small cell lung cancer 3 | 2,890
primitive neuroectodermal tumor 3 | 3,035
Acidosis, Lactic 2 | 97
Animal Mammary Neoplasms 2 | 136
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Breast Neoplasms 2 | 445
Breast cancer 2 | 3,578
Cataract 4 multiple types 2 | 14
Cognitive delay 2 | 608
Cutaneous anthrax 2 | 8
Epilepsy 2 | 792
Global developmental delay 2 | 608
Hepatomegaly 2 | 285
Intellectual disability 2 | 1,016
Lactic acidemia 2 | 95
Leigh disease 2 | 100
Mammary Neoplasms 2 | 425
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Mental and motor retardation 2 | 608
Multiple myeloma 2 | 1,332
Neonatal Hypotonia 2 | 64
Neoplasm Metastasis 2 | 168
Nystagmus 2 | 317
Retinitis pigmentosa 49 2 | 14
Seizures 2 | 596
Small head 2 | 374
Stomach Neoplasms 2 | 300
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
sonic hedgehog group medulloblastoma 2 | 467
Abnormal coordination 1 | 15
Adult onset 1 | 82
Autosomal dominant cerebellar ataxia 1 | 33
Candidiasis 1 | 55
Carcinoma, Renal Cell 1 | 124
Cardiomyopathy 1 | 116
Death in early childhood 1 | 82
Death in infancy 1 | 82
Degenerative polyarthritis 1 | 115
Dilated ventricles (finding) 1 | 121
Diphtheria 1 | 40
Downward slant of palpebral fissure 1 | 158
Dysarthria 1 | 192
Encephalopathies 1 | 43
Enophthalmos 1 | 75
Esophageal Neoplasms 1 | 69
Foramen Ovale, Patent 1 | 10
Hemolytic anemia 1 | 77
Hyperammonemia 1 | 30
Hypsarrhythmia 1 | 25
Impaired cognition 1 | 96
Increased serum lactate 1 | 60
Inverted V-shaped upper lip 1 | 19
Low Vision 1 | 174
MYELODYSPLASTIC SYNDROME 1 | 53
Mental impairment 1 | 95
Muscle Weakness 1 | 170
Neuroectodermal tumor 1 | 3
Osteoarthritis 1 | 184
Polymicrogyria 1 | 48
Reduced fetal movement 1 | 51
Renal Cell Carcinoma 1 | 214
Respiratory Failure 1 | 104
Salmonellosis 1 | 42
Severe mental retardation (I.Q. 20-34) 1 | 99
Shwachman-Diamond syndrome 1 | 17
Slow progression 1 | 89
Sunken eyes 1 | 63
Tented mouth 1 | 19
Tented upper lip 1 | 19
Thalassemia 1 | 53
Tremor 1 | 113
Visual Impairment 1 | 174
posterior fossa group A ependymoma 1 | 468
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Non-IDG 18 | 12,091

GO Function

translation elongation factor ... 18 | 18
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Elongation factor G, mitochondrial GFM1 Tbio Non-IDG -2.39993 250.5 121
Eukaryotic translation initiation factor 5A-1 EIF5A Tbio Non-IDG -2.10288 142.0 231
Eukaryotic translation initiation factor 5A-1-like EIF5AL1 Tdark Non-IDG 0.00000 1.00 54
Elongation factor 2 EEF2 Tchem Non-IDG -2.95619 938.4 363
Putative elongation factor 1-alpha-like 3 EEF1A1P5 Tdark Non-IDG -2.81422 1183.0 0
Elongation factor-like GTPase 1 EFL1 Tbio Non-IDG -1.31803 19.5 65
Selenocysteine-specific elongation factor EEFSEC Tbio Non-IDG -1.87910 68.1 87
Putative elongation factor 1-delta-like protein EEF1DP3 Tdark Non-IDG 0.00000 0
Elongation factor Tu, mitochondrial TUFM Tbio Non-IDG -1.25874 21.1 216
Elongation factor Ts, mitochondrial TSFM Tbio Non-IDG -2.30763 199.4 123