Development Level

Tbio 15 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

abnormal bone structure 1 | 187
decreased NK T cell number 1 | 2
decreased bone mineral content 1 | 151
decreased circulating bilirubi... 1 | 19
increased blood urea nitrogen ... 1 | 48
premature death 1 | 5
preweaning lethality, incomple... 1 | 499

Disease

psoriasis 11 | 6,694
Carcinoma 10 | 11,493
Breast cancer 7 | 3,578
medulloblastoma, large-cell 7 | 6,241
atypical teratoid / rhabdoid tumor 6 | 5,112
pancreatic cancer 6 | 2,398
Alzheimer's disease 5 | 658
Atopic dermatitis 5 | 952
Kidney cancer 5 | 2,613
adult high grade glioma 5 | 3,801
cystic fibrosis 5 | 1,696
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
nasopharyngeal carcinoma 5 | 1,058
ovarian cancer 5 | 8,520
Astrocytoma, Pilocytic 4 | 3,081
DOID:2627 4 | 94
Endometrial cancer 4 | 311
Pick disease 4 | 1,894
group 3 medulloblastoma 4 | 4,104
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
osteosarcoma 4 | 7,950
subependymal giant cell astrocytoma 4 | 2,287
Cancer 3 | 2,499
Polycystic ovary syndrome 3 | 360
Rheumatoid arthritis 3 | 1,191
Waldenstrons macroglobulinemia 3 | 765
astrocytic glioma 3 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
periodontitis 3 | 293
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074
Amyotrophic lateral sclerosis 2 | 451
Dementia 2 | 175
Duchenne muscular dystrophy 2 | 601
Endometriosis 2 | 540
Ichthyosis vulgaris 2 | 11
Large intestine cancer 2 | 126
Liver cancer 2 | 604
Melanoma 2 | 711
Nerve Degeneration 2 | 121
Neurodegenerative disease 2 | 414
Parkinson's disease 2 | 392
Parkinsonian Disorders 2 | 56
Schizophrenia 2 | 1,160
Skin cancer 2 | 469
active ulcerative colitis 2 | 764
aldosterone-producing adenoma 2 | 665
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
nephrosclerosis 2 | 333
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Anxiety Disorders 1 | 38
Brain disease 1 | 96
Brain hemorrhage 1 | 14
Cerebral Hemorrhage 1 | 42
Cerebral amyloid angiopathy 1 | 13
Comatose 1 | 56
Deglutition Disorders 1 | 132
Delusions 1 | 11
Eczema herpeticum 1 | 7
Epidermolytic hyperkeratosis 1 | 14
Forgetful 1 | 40
Hallucinations, Visual 1 | 6
Headache 1 | 37
Hyperparathyroidism 1 | 48
Intermittent migraine headaches 1 | 68
Memory Loss 1 | 40
Memory impairment 1 | 40
Migraine Disorders 1 | 76
Myoclonus 1 | 74
Necrosis 1 | 53
Neoplasm Metastasis 1 | 168
Neurodegenerative Disorders 1 | 79
Paralysed 1 | 42
Paralysis 1 | 9
Paresthesia 1 | 32
Peeling skin syndrome 1 | 17
Rickets 1 | 49
Schnyder Corneal Dystrophy 1 | 23
Spinal Cord Diseases 1 | 3
Weight Gain 1 | 100
X-linked cerebral adrenoleukodystrophy 1 | 116
non-small cell lung carcinoma 1 | 317

Tissue

Digestive Tract 17 | 17,369
Female tissues 17 | 17,400
Endocrine System 16 | 18,159
Skin and soft tissues 16 | 17,230
Blood and immune system 15 | 16,909
Liver and Pancreas 13 | 16,750
Nervous System 12 | 16,725
Male tissues 11 | 17,142
Urinary Tract 11 | 16,678
Cardiovascular System 10 | 15,192
Respiratory system 10 | 16,393

Target Family

Non-IDG 18 | 12,091
Enzyme 1 | 4,145

GO Function

transition metal ion binding 19 | 19
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hornerin HRNR Tbio Non-IDG -1.33117 22.2 69
Protein S100-P S100P Tbio Non-IDG -1.30194 23.0 190
Amyloid-like protein 1 APLP1 Tbio Non-IDG -1.88769 62.6 162
Filaggrin-2 FLG2 Tbio Non-IDG -2.12789 127.8 35
Sentan SNTN Tdark Non-IDG -0.71321 3.95 6
Protein S100-A2 S100A2 Tbio Non-IDG -1.90538 88.6 127
Beta-synuclein SNCB Tbio Non-IDG -2.05833 98.5 287
Amyloid-like protein 2 APLP2 Tbio Non-IDG -2.04768 101.3 279
Protein S100-A7A S100A7A Tdark Non-IDG -0.55059 3.38 19
Protein S100-G S100G Tbio Non-IDG -2.39812 272.5 38