Development Level

Tbio 37 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
hypoactivity 3 | 132
decreased vertical activity 2 | 208
abnormal eyelid morphology 1 | 7
abnormal gait 1 | 69
abnormal head size 1 | 6
abnormal iris morphology 1 | 13
abnormal placement of pupils 1 | 6
corneal opacity 1 | 32
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased circulating creatini... 1 | 39
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating potassiu... 1 | 29
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
irregularly shaped pupil 1 | 7
male infertility 1 | 123
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Carcinoma 25 | 11,493
psoriasis 20 | 6,694
lung cancer 17 | 4,740
ovarian cancer 17 | 8,520
osteosarcoma 16 | 7,950
Cancer 13 | 2,499
glioblastoma 13 | 5,792
atypical teratoid / rhabdoid tumor 11 | 5,112
malignant mesothelioma 11 | 3,232
adult high grade glioma 10 | 3,801
ependymoma 10 | 4,679
group 3 medulloblastoma 10 | 4,104
Astrocytoma, Pilocytic 9 | 3,081
ductal carcinoma in situ 9 | 1,745
interstitial cystitis 9 | 2,312
lung adenocarcinoma 9 | 2,716
Breast cancer 8 | 3,578
Osteoarthritis 8 | 184
lung carcinoma 8 | 2,843
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
diabetes mellitus 7 | 1,728
invasive ductal carcinoma 7 | 2,951
medulloblastoma, large-cell 7 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
primitive neuroectodermal tumor 7 | 3,035
Liver Cirrhosis, Experimental 6 | 769
Premature ovarian failure 6 | 65
colon cancer 6 | 1,478
non-small cell lung cancer 6 | 2,890
Acquired scoliosis 5 | 281
Atopic dermatitis 5 | 952
Autosomal recessive predisposition 5 | 1,442
Cleft Palate 5 | 271
Curvature of spine 5 | 282
Kidney cancer 5 | 2,613
Osteoporosis 5 | 363
Polycystic ovary syndrome 5 | 360
Right atrial isomerism 5 | 29
Ureteral obstruction 5 | 33
group 4 medulloblastoma 5 | 1,855
oligodendroglioma 5 | 2,850
pituitary cancer 5 | 1,972
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Ankylosis 4 | 28
Brachydactyly 4 | 156
Congenital heart disease 4 | 93
Coronary artery disease 4 | 268
Degenerative polyarthritis 4 | 115
Infertility 4 | 188
Kidney disease 4 | 430
Microphthalmia 4 | 76
Otosclerosis 4 | 15
Pick disease 4 | 1,894
Pulmonary Fibrosis 4 | 106
Visceral heterotaxy 4 | 14
astrocytic glioma 4 | 2,597
cutaneous lupus erythematosus 4 | 1,057
pediatric high grade glioma 4 | 1,064
Amenorrhea 3 | 58
Aortic Valve Insufficiency 3 | 40
Arthritis, Rheumatoid 3 | 174
Asthma 3 | 385
Bilateral fifth finger clinodactyly 3 | 110
Breast Neoplasms 3 | 445
Carcinoma, Hepatocellular 3 | 228
Craniofacial Abnormalities 3 | 151
Curvature of little finger 3 | 110
Endometriosis 3 | 540
Exophthalmos 3 | 112
Heart disease 3 | 306
Hernia, Inguinal 3 | 89
Hypertension 3 | 396
Liver carcinoma 3 | 240
Liver disease 3 | 237
Mammary Neoplasms 3 | 425
Multiple myeloma 3 | 1,332
Pneumonia 3 | 174
Pre-Eclampsia 3 | 68
Prominent eyes 3 | 96
Prominent globes 3 | 96
Prostatic Neoplasms 3 | 495
Protruding eyes 3 | 96
Rheumatoid arthritis 3 | 1,191
Situs ambiguus 3 | 25
Vascular disease 3 | 319
Waldenstrons macroglobulinemia 3 | 765
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
head and neck cancer 3 | 271
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung carcinoma 3 | 317
pancreatic cancer 3 | 2,398
posterior fossa group B ependymoma 3 | 416
sonic hedgehog group medulloblastoma 3 | 467
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Endocrine System 41 | 18,159
Female tissues 39 | 17,400
Liver and Pancreas 38 | 16,750
Digestive Tract 37 | 17,369
Nervous System 37 | 16,725
Skin and soft tissues 37 | 17,230
Male tissues 36 | 17,142
Urinary Tract 36 | 16,678
Blood and immune system 34 | 16,909
Cardiovascular System 34 | 15,192
Respiratory system 34 | 16,393

Target Family

Non-IDG 35 | 12,091
Enzyme 4 | 4,145
Transcription Factor 2 | 1,400

GO Function

transforming growth factor bet... 41 | 41
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Transforming growth factor-beta receptor-associated protein 1 TGFBRAP1 Tbio Non-IDG -1.03126 9.10 179
Ubiquitin carboxyl-terminal hydrolase 15 USP15 Tbio Enzyme -1.64742 41.6 242
Embryonic growth/differentiation factor 1 GDF1 Tbio Non-IDG -2.00590 102.6 64
Muellerian-inhibiting factor AMH Tbio Non-IDG -3.43406 2729.3 264
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Bone morphogenetic protein 3 BMP3 Tbio Non-IDG -2.11354 130.5 361
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
Growth/differentiation factor 6 GDF6 Tbio Non-IDG -2.31035 205.4 110