Development Level

Tbio 2 | 11,445

Disease

Cancer 2 | 2,499
ovarian cancer 2 | 8,520
subependymal giant cell astrocytoma 2 | 2,287
ANEURYSM, INTRACRANIAL BERRY, 1 (disorder) 1 | 3
Abdominal pain, episodic 1 | 9
Aneurysm of celiac artery 1 | 1
Angiodysplasia 1 | 5
Angioectasias of the lip 1 | 4
Angioectasias of the tongue 1 | 2
Angiofibroma 1 | 7
Arteriovenous Malformations, Cerebral 1 | 2
Arteriovenous fistulas of celiac and mesenteric vessels 1 | 3
Arteriovenous malformation 1 | 6
Arteriovenous malformation of liver 1 | 2
Brain Abscess 1 | 2
Brain hemorrhage 1 | 14
COPD 1 | 118
Carney complex 1 | 25
Cerebral Hemorrhage 1 | 42
Chloracne 1 | 32
Cholecystitis 1 | 18
Clubbing 1 | 9
Conjunctival telangiectasis 1 | 14
Cyanosis 1 | 17
Dyspnea 1 | 76
Erythrocytosis 1 | 8
Esophagitis 1 | 35
Familial primary pulmonary hypertension 1 | 11
Feces color: tarry 1 | 2
Finger pad telangiectases 1 | 2
Gastrointestinal angiodysplasia 1 | 3
Gastrointestinal arteriovenous malformation 1 | 2
Gastrointestinal telangiectasia 1 | 2
Growth hormone excess 1 | 14
Hemangioma, Cavernous 1 | 20
Hematemesis 1 | 4
Hematochezia 1 | 9
Hepatocellular Adenoma 1 | 10
Hereditary hemorrhagic telangiectasia 1 | 13
High-output congestive heart failure 1 | 1
Hypercalcemia 1 | 59
Hyperinsulinaemic hypoglycaemia 1 | 16
Hyperinsulinemia, fasting 1 | 7
Hypertension, Portal 1 | 22
Increased serum parathyroid hormone 1 | 14
Insulinoma 1 | 24
Intermittent migraine headaches 1 | 68
Intestinal Neoplasms 1 | 12
Iron-Refractory Iron Deficiency Anemia 1 | 15
Ischemic stroke 1 | 4
Juvenile polyposis syndrome 1 | 7
Kidney Neoplasm 1 | 29
Kidney Neoplasms 1 | 37
Lip telangiectases 1 | 4
Melena 1 | 2
Mesenteric artery aneurysm 1 | 1
Metabolic syndrome X 1 | 52
Migraine Disorders 1 | 76
Multiple Endocrine Neoplasia Type 1 1 | 29
Multiple endocrine neoplasia type 2A 1 | 20
Multiple endocrine neoplasia type 4 1 | 5
Nail bed telangiectases 1 | 2
Nasal mucosa telangiectasia 1 | 2
Non-Functioning Pituitary Gland Neoplasm 1 | 6
Ovarian Neoplasms 1 | 102
Palatal spider veins 1 | 2
Palate telangiectases 1 | 2
Parathyroid Adenoma 1 | 19
Parathyroid hyperplasia 1 | 6
Peptic Ulcer 1 | 27
Pituitary Neoplasms 1 | 6
Pituitary growth hormone cell adenoma 1 | 8
Polycythemia 1 | 25
Primary hyperparathyroidism 1 | 5
Primary pulmonary hypertension 1 | 14
Prolactinoma 1 | 11
Prostatic Intraepithelial Neoplasia 1 | 11
Prostatic Intraepithelial Neoplasias 1 | 11
Pulmonary arteriovenous malformation 1 | 2
Rectal Neoplasms 1 | 18
Right to left cardiovascular shunt (finding) 1 | 3
Sezary Syndrome 1 | 27
Spider veins of the lip 1 | 4
Spinal arteriovenous malformation 1 | 2
Spontaneous haematoma 1 | 8
Spontaneous, recurrent epistaxis 1 | 3
Subarachnoid Hemorrhage 1 | 7
Subcutaneous lipomas 1 | 9
Telangiectasia of the skin 1 | 39
Telangiectasia, Hereditary Hemorrhagic 1 | 3
Telangiectasia, Hereditary Hemorrhagic, of Rendu, Osler, and Weber 1 | 1
Telangiectasis 1 | 36
Thyroid Gland Follicular Adenoma 1 | 9
Tongue telangiectasia 1 | 2
Uterine Neoplasms 1 | 9
Venous varicosities of celiac and mesenteric vessels 1 | 1
Visceral angiomatosis 1 | 13
Zollinger-Ellison syndrome 1 | 18
intermittent abdominal pain 1 | 9
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 1 | 4,145
Non-IDG 1 | 12,091

GO Function

transforming growth factor bet... 2 | 2
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Cyclin-dependent kinase inhibitor 1B CDKN1B Tbio Enzyme -3.11753 1246.6 1886