Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal bone structure 2 | 187
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal lens morphology 1 | 81
abnormal locomotor activation 1 | 16
abnormal pupil morphology 1 | 2
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
enlarged heart 1 | 210
increased B cell number 1 | 9
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 9 | 11,493
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
medulloblastoma, large-cell 5 | 6,241
Breast cancer 4 | 3,578
Kidney cancer 4 | 2,613
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
primitive neuroectodermal tumor 4 | 3,035
Crohn's disease 3 | 321
Intellectual disability 3 | 1,016
invasive ductal carcinoma 3 | 2,951
lung cancer 3 | 4,740
pancreatic cancer 3 | 2,398
psoriasis 3 | 6,694
tuberculosis 3 | 2,010
Acquired metabolic disease 2 | 336
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Diabetes Mellitus, Insulin-Dependent 2 | 48
Diabetes Mellitus, Type 1 2 | 43
Dull intelligence 2 | 645
Liver cancer 2 | 604
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Poor school performance 2 | 645
Short stature 2 | 531
Type 2 diabetes mellitus 2 | 272
Waldenstrons macroglobulinemia 2 | 765
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
cystic fibrosis 2 | 1,696
cystic fibrosis and chronic rhinosinusitis 2 | 214
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Abdomen distended 1 | 43
Accessory rib 1 | 10
Acute Promyelocytic Leukemia 1 | 40
Cleft palate with cleft lip 1 | 23
Coarse facial features 1 | 108
Common variable immunodeficiency 1 | 101
Constipation 1 | 181
Corpus Callosum, Agenesis Of, With Abnormal Genitalia 1 | 1
Crohn Disease 1 | 45
Dyschezia 1 | 135
ENSP00000256078 1 | 30
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 1 1 | 5
Early infantile epileptic encephalopathy with suppression bursts 1 | 10
Fatigue 1 | 182
Fibular hypoplasia 1 | 9
Gaucher disease type 1 1 | 180
Generalized osteopenia 1 | 99
Holoprosencephaly 1 | 56
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Icterus 1 | 82
Insulin Resistance 1 | 72
Large bregma sutures 1 | 46
Large fontanelle 1 | 46
Large, late-closing fontanelle 1 | 46
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Leukemia, Promyelocytic, Acute 1 | 36
Lissencephaly 2, X-linked 1 | 1
Lissencephaly, X-Linked, 2 1 | 1
MENTAL RETARDATION, X-LINKED, WITH OR WITHOUT SEIZURES, ARX-RELATED (disorder) 1 | 1
Mental Retardation, X-Linked, With Or Without Seizures, Arx-Related 1 | 1
Neonatal hypoglycemia 1 | 17
Oral cleft 1 | 18
Osteopenia 1 | 99
PARTINGTON X-LINKED MENTAL RETARDATION SYNDROME 1 | 1
Pain agnosia 1 | 104
Partington syndrome 1 | 9
Proud Syndrome 1 | 1
Short tibia 1 | 9
Sleep disturbances 1 | 37
Small testicle 1 | 75
Systemic lupus erythematosus 1 | 194
Thickened facial skin with coarse facial features 1 | 108
Thyrotoxicosis 1 | 38
Vitiligo 1 | 73
West Syndrome 1 | 28
Wide bregma sutures 1 | 46
chronic kidney disease 1 | 90
non-Hodgkin lymphoma 1 | 6
sarcoidosis 1 | 370

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Male tissues 10 | 17,142
Liver and Pancreas 9 | 16,750
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Cardiovascular System 7 | 15,192

Target Family

Transcription Factor 10 | 1,400
Nuclear Receptor 1 | 48

GO Function

transcriptional repressor acti... 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein ARX ARX Tbio Transcription Factor -2.21255 163.7 328
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.90906 89.8 184
Zinc finger protein 40 HIVEP1 Tbio Transcription Factor -1.34659 23.7 25
GDNF-inducible zinc finger protein 1 GZF1 Tbio Transcription Factor -0.34461 3.36 48
Zinc finger protein 831 ZNF831 Tdark Transcription Factor 0.95 0.11 6
Zinc finger and BTB domain-containing protein 16 ZBTB16 Tbio Transcription Factor -2.31797 210.0 275
Homeobox protein prophet of Pit-1 PROP1 Tbio Transcription Factor -2.15448 151.2 67
Musculin MSC Tbio Transcription Factor -2.18402 156.4 184
Nuclear receptor subfamily 1 group D member 2 NR1D2 Tchem Nuclear Receptor -1.77473 57.5 205
Paired box protein Pax-4 PAX4 Tbio Transcription Factor -2.13674 146.6 229