Development Level

Tbio 14 | 11,445
Tchem 2 | 1,598
Tclin 2 | 613

IMPC Phenotype

abnormal vertebrae morphology 1 | 18
decreased circulating serum al... 1 | 82
decreased mean corpuscular vol... 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased lactate dehydrogenas... 1 | 3
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 11 | 11,493
ovarian cancer 11 | 8,520
osteosarcoma 9 | 7,950
psoriasis 9 | 6,694
Cancer 8 | 2,499
breast carcinoma 8 | 1,638
glioblastoma 8 | 5,792
medulloblastoma, large-cell 8 | 6,241
Breast cancer 7 | 3,578
Obesity 7 | 678
Schizophrenia 7 | 1,160
diabetes mellitus 7 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung cancer 7 | 4,740
atypical teratoid / rhabdoid tumor 6 | 5,112
Astrocytoma, Pilocytic 5 | 3,081
group 4 medulloblastoma 5 | 1,855
non-small cell lung cancer 5 | 2,890
Alzheimer's disease 4 | 658
Depressive disorder 4 | 409
Epilepsy 4 | 792
Hypertension 4 | 396
Liver disease 4 | 237
Mental Depression 4 | 333
Parkinson's disease 4 | 392
Rheumatoid arthritis 4 | 1,191
astrocytoma 4 | 1,146
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Arthritis, Juvenile 3 | 126
Bipolar Disorder 3 | 666
Brachydactyly 3 | 156
Breast Neoplasms 3 | 445
Carcinoma, Hepatocellular 3 | 228
Cell Transformation, Neoplastic 3 | 97
Cerebrovascular disease 3 | 238
Constipation 3 | 181
Down syndrome 3 | 499
Heart disease 3 | 306
Hyperglycemia 3 | 137
Hypertensive disease 3 | 292
Juvenile arthritis 3 | 126
Kidney cancer 3 | 2,613
Liver carcinoma 3 | 240
Liver neoplasms 3 | 130
Major Depressive Disorder 3 | 301
Mammary Neoplasms 3 | 425
Mood Disorders 3 | 184
Neuropathy 3 | 261
Reperfusion Injury 3 | 86
Tetralogy of Fallot 3 | 63
Toxic encephalopathy 3 | 141
Unipolar Depression 3 | 250
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
chronic lymphosyte leukemia 3 | 204
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
fascioscapulohumeral muscular dystrophy 3 | 100
fibroadenoma 3 | 559
gastric cancer 3 | 459
juvenile dermatomyositis 3 | 1,187
malignant mesothelioma 3 | 3,232
nephrosclerosis 3 | 333
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
tuberculosis 3 | 2,010
Arthritis 2 | 290
Atherosclerosis 2 | 291
Bilateral fifth finger clinodactyly 2 | 110
Cocaine-Related Disorders 2 | 92
Colonic Neoplasms 2 | 142
Curvature of little finger 2 | 110
Dementia 2 | 175
Eye disease 2 | 62
Hepatomegaly 2 | 285
Hypoglycemia 2 | 152
Kidney disease 2 | 430
Lung Neoplasms 2 | 232
Myocardial Ischemia 2 | 169
Seizures 2 | 596
Status Epilepticus 2 | 98
chronic rhinosinusitis 2 | 512
hepatocellular carcinoma 2 | 547
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
pterygium 2 | 76
urothelial carcinoma 2 | 318

Tissue

Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Cardiovascular System 14 | 15,192
Respiratory system 14 | 16,393

Target Family

Transcription Factor 12 | 1,400
Non-IDG 2 | 12,091
Nuclear Receptor 2 | 48
Enzyme 1 | 4,145
TF/Epigenetic 1 | 38

GO Function

transcriptional activator acti... 18 | 18
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.89447 774.1 686
Transcription factor SOX-10 SOX10 Tbio Transcription Factor -2.69195 478.2 389
Homeobox protein MIXL1 MIXL1 Tbio Transcription Factor -2.76027 560.5 117
Pituitary homeobox 1 PITX1 Tbio Transcription Factor -2.49247 314.9 173
Nuclear factor erythroid 2-related factor 1 NFE2L1 Tbio Transcription Factor -1.57346 40.9 157
Proto-oncogene c-Fos FOS Tbio Transcription Factor -4.14231 13598.8 1058
Bile acid receptor NR1H4 Tclin Nuclear Receptor -2.57379 350.3 293
Circadian locomoter output cycles protein kaput CLOCK Tbio TF/Epigenetic -2.63013 392.7 323
Rhombotin-2 LMO2 Tbio Non-IDG -2.28226 199.0 560
Homeobox protein GBX-2 GBX2 Tbio Transcription Factor -1.75250 59.9 240