Development Level

Tbio 34 | 10,625
Tchem 9 | 1,890
Tdark 4 | 7,003
Tclin 2 | 602

IMPC Phenotype

increased circulating alkaline... 3 | 119
preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
abnormal optic disc morphology 2 | 10
decreased body length 2 | 108
increased grip strength 2 | 83
short tibia 2 | 82
abnormal bone mineralization 1 | 55
abnormal coat-hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retinal pigmentation 1 | 61
abnormal skin condition 1 | 6
abnormal spinal cord morpholog... 1 | 8
abnormal tooth morphology 1 | 24
absent seminal vesicle 1 | 2
corneal opacity 1 | 25
decreased circulating amylase ... 1 | 24
decreased circulating sodium l... 1 | 18
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased thermal nociceptive ... 1 | 4
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
female infertility 1 | 34
hyperactivity 1 | 108
increased circulating free fat... 1 | 17
increased leukocyte cell numbe... 1 | 37
increased sacral vertebrae num... 1 | 62
increased thermal nociceptive ... 1 | 9
irregularly shaped pupil 1 | 7
male infertility 1 | 62
mydriasis 1 | 9
oligodactyly 1 | 14
prenatal lethality 1 | 16
preweaning lethality, complete... 1 | 633
small testis 1 | 37
straub tail 1 | 26
vertebral transformation 1 | 12

Disease

ovarian cancer 27 | 8,491
osteosarcoma 25 | 7,933
psoriasis 25 | 6,685
Cancer 24 | 2,346
lung cancer 22 | 4,473
glioblastoma 18 | 5,572
medulloblastoma, large-cell 16 | 6,234
atypical teratoid / rhabdoid tumor 15 | 4,369
malignant mesothelioma 14 | 3,163
non-small cell lung cancer 14 | 2,798
oligodendroglioma 12 | 2,849
primitive neuroectodermal tumor 12 | 3,031
subependymal giant cell astrocytoma 12 | 2,287
invasive ductal carcinoma 11 | 2,950
group 4 medulloblastoma 10 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
pancreatic cancer 9 | 2,300
Breast cancer 8 | 3,098
Carcinoma 8 | 2,147
breast carcinoma 8 | 1,614
interstitial cystitis 8 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
lung adenocarcinoma 8 | 2,714
pediatric high grade glioma 8 | 2,712
pituitary cancer 8 | 1,972
astrocytoma 7 | 1,493
diabetes mellitus 7 | 1,663
ductal carcinoma in situ 7 | 1,745
ependymoma 7 | 2,514
sonic hedgehog group medulloblastoma 7 | 1,482
Rheumatoid Arthritis 6 | 1,170
astrocytic glioma 6 | 2,241
colon cancer 6 | 1,475
cystic fibrosis 6 | 1,670
group 3 medulloblastoma 6 | 2,254
spina bifida 6 | 1,064
ulcerative colitis 6 | 2,087
Endometriosis 5 | 535
Multiple myeloma 5 | 1,327
acute myeloid leukemia 5 | 785
cutaneous lupus erythematosus 5 | 1,056
non primary Sjogren syndrome sicca 5 | 840
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
Acquired metabolic disease 4 | 267
Pick disease 4 | 1,893
Prostatic Neoplasms 4 | 471
Seasonal affective disorder 4 | 25
Vascular disease 4 | 281
aldosterone-producing adenoma 4 | 664
dermatomyositis 4 | 966
gastric carcinoma 4 | 832
hepatocellular carcinoma 4 | 550
lung carcinoma 4 | 2,844
pilocytic astrocytoma 4 | 3,086
primary pancreatic ductal adenocarcinoma 4 | 1,271
Adenoid Cystic Carcinoma 3 | 99
Bipolar Disorder 3 | 266
Diabetes Mellitus, Non-Insulin-Dependent 3 | 161
Down syndrome 3 | 548
Juvenile arthritis 3 | 124
Myeloid Leukemia, Chronic 3 | 22
Persistent hyperplastic primary vitreous 3 | 20
Squamous cell carcinoma 3 | 96
Toxic encephalopathy 3 | 131
acute quadriplegic myopathy 3 | 1,157
adrenocortical carcinoma 3 | 1,427
atypical teratoid/rhabdoid tumor 3 | 1,095
chronic rhinosinusitis 3 | 512
esophageal adenocarcinoma 3 | 737
inflammatory breast cancer 3 | 404
nasopharyngeal carcinoma 3 | 1,056
nephrosclerosis 3 | 329
ovarian neoplasm 3 | 97
posterior fossa group A ependymoma 3 | 1,511
posterior fossa group B ependymoma 3 | 1,530
tuberculosis 3 | 1,563
Allergic rhinitis 2 | 92
Alzheimer's disease 2 | 644
Amyotrophic Lateral Sclerosis 2 | 432
Anemia 2 | 252
Autistic Disorder 2 | 320
Brain Ischemia 2 | 87
Cholestasis 2 | 93
Colonic Neoplasms 2 | 126
Congenital Heart Defects 2 | 37
Infertility 2 | 163
Inflammation 2 | 109
Liver neoplasms 2 | 108
Male infertility 2 | 170
Parkinson's disease 2 | 364
Peripheral Neuropathy 2 | 303
Waldenstrons macroglobulinemia 2 | 764
adult high grade glioma 2 | 2,148
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
juvenile dermatomyositis 2 | 1,189
non-small cell lung carcinoma 2 | 413
pancreatic carcinoma 2 | 567
progressive supranuclear palsy 2 | 674
pterygium 2 | 74

Tissue

Liver and Pancreas 48 | 18,135
Blood and immune system 47 | 17,994
Female tissues 47 | 18,646
Nervous System 47 | 18,560
Cardiovascular System 46 | 17,957
Digestive Tract 46 | 18,472
Endocrine System 46 | 18,511
Male tissues 46 | 17,968
Urinary Tract 46 | 18,443
Respiratory system 45 | 17,483
Skin and soft tissues 45 | 18,114

Target Family

Transcription Factor 25 | 1,400
Non-IDG 13 | 11,969
Epigenetic 6 | 242
Nuclear Receptor 3 | 48
Enzyme 2 | 4,146

GO Function

transcription regulatory regio... 49 | 49
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine-threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-lysine N-methyltransferase SUV39H1 SUV39H1 Tchem Epigenetic -2.21810 149.4 267
Paired amphipathic helix protein Sin3a SIN3A Tbio Non-IDG -1.89468 62.9 159
POU domain, class 5, transcription factor 1 POU5F1 Tbio Transcription Factor -3.28009 1980.8 817
Lysine-specific demethylase hairless HR Tbio Enzyme -1.09980 60.2 86
Probable JmjC domain-containing histone demethylation protein 2C JMJD1C Tbio Epigenetic -1.16854 16.4 86
Nuclear factor erythroid 2-related factor 1 NFE2L1 Tbio Transcription Factor -1.51817 36.8 131
Zinc finger protein 658 ZNF658 Tbio Transcription Factor 0.27 1.07 22
Trans-acting T-cell-specific transcription factor GATA-3 GATA3 Tbio Transcription Factor -3.17162 1432.1 558
Transcription factor SOX-11 SOX11 Tbio Transcription Factor -1.94723 92.4 211
MKL/myocardin-like protein 1 MKL1 Tbio Non-IDG -2.47847 316.3 178