Development Level

Tbio 37 | 11,445
Tchem 7 | 1,598
Tdark 6 | 6,588
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased startle reflex 2 | 112
preweaning lethality, complete... 2 | 979
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin condition 1 | 6
abnormal tooth morphology 1 | 24
absent seminal vesicle 1 | 4
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
female infertility 1 | 60
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased lactate dehydrogenas... 1 | 3
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
irregularly shaped pupil 1 | 7
male infertility 1 | 123
mammalian phenotype 1 | 17
mydriasis 1 | 6
prenatal lethality 1 | 28
short tibia 1 | 97
small testis 1 | 58
small uterus 1 | 3
vertebral transformation 1 | 12

Disease

Carcinoma 40 | 11,493
ovarian cancer 26 | 8,520
osteosarcoma 25 | 7,950
psoriasis 24 | 6,694
lung cancer 23 | 4,740
Cancer 22 | 2,499
glioblastoma 20 | 5,792
atypical teratoid / rhabdoid tumor 18 | 5,112
medulloblastoma, large-cell 17 | 6,241
group 3 medulloblastoma 15 | 4,104
non-small cell lung cancer 15 | 2,890
malignant mesothelioma 14 | 3,232
primitive neuroectodermal tumor 14 | 3,035
oligodendroglioma 13 | 2,850
invasive ductal carcinoma 12 | 2,951
subependymal giant cell astrocytoma 12 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
interstitial cystitis 10 | 2,312
pancreatic cancer 10 | 2,398
Breast cancer 9 | 3,578
Kidney cancer 9 | 2,613
astrocytic glioma 9 | 2,597
breast carcinoma 9 | 1,638
ependymoma 9 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
adult high grade glioma 8 | 3,801
diabetes mellitus 8 | 1,728
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung adenocarcinoma 8 | 2,716
pituitary cancer 8 | 1,972
cystic fibrosis 7 | 1,696
ductal carcinoma in situ 7 | 1,745
Liver cancer 6 | 604
Obesity 6 | 678
Rheumatoid arthritis 6 | 1,191
colon cancer 6 | 1,478
non primary Sjogren syndrome sicca 6 | 891
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
spina bifida 6 | 1,074
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
Astrocytoma, Pilocytic 5 | 3,081
Bipolar Disorder 5 | 666
Depressive disorder 5 | 409
Epilepsy 5 | 792
Multiple myeloma 5 | 1,332
Muscle hypotonia 5 | 571
Prostatic Neoplasms 5 | 495
Schizophrenia 5 | 1,160
Short stature 5 | 531
Strabismus 5 | 270
acute myeloid leukemia 5 | 783
aldosterone-producing adenoma 5 | 665
astrocytoma 5 | 1,146
hepatocellular carcinoma 5 | 547
lung carcinoma 5 | 2,843
Acquired metabolic disease 4 | 336
Alzheimer's disease 4 | 658
Broad flat nasal bridge 4 | 236
Congenital deafness 4 | 185
Cryptorchidism 4 | 296
Deafness 4 | 198
Endometriosis 4 | 540
Hearing Loss, Partial 4 | 185
Intellectual disability 4 | 1,016
Mental Depression 4 | 333
Nasal bridge wide 4 | 236
Nystagmus 4 | 317
Penile hypospadias 4 | 106
Pick disease 4 | 1,894
Seasonal affective disorder 4 | 28
Seizures 4 | 596
Small head 4 | 374
Vascular disease 4 | 319
adrenocortical carcinoma 4 | 1,428
chronic rhinosinusitis 4 | 512
cutaneous lupus erythematosus 4 | 1,057
dermatomyositis 4 | 966
hearing impairment 4 | 199
nasopharyngeal carcinoma 4 | 1,058
nephrosclerosis 4 | 333
pediatric high grade glioma 4 | 1,064
primary pancreatic ductal adenocarcinoma 4 | 1,109
sonic hedgehog group medulloblastoma 4 | 467
Abnormality of cardiovascular system morphology 3 | 23
Adenoid Cystic Carcinoma 3 | 99
Anemia 3 | 365
Arthritis, Juvenile 3 | 126
Cholestasis 3 | 155
Down syndrome 3 | 499
Juvenile arthritis 3 | 126
Liver neoplasms 3 | 130
Lung Neoplasms 3 | 232
Mood Disorders 3 | 184
Parkinson's disease 3 | 392
Upward slant of palpebral fissure 3 | 75
acute quadriplegic myopathy 3 | 1,158
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807

Tissue

Digestive Tract 51 | 17,369
Endocrine System 51 | 18,159
Female tissues 51 | 17,400
Skin and soft tissues 51 | 17,230
Blood and immune system 49 | 16,909
Male tissues 49 | 17,142
Respiratory system 49 | 16,393
Liver and Pancreas 48 | 16,750
Nervous System 48 | 16,725
Urinary Tract 48 | 16,678
Cardiovascular System 46 | 15,192

Target Family

Transcription Factor 29 | 1,400
Non-IDG 13 | 12,091
Epigenetic 6 | 242
Nuclear Receptor 3 | 48
Enzyme 2 | 4,145

GO Function

transcription regulatory regio... 53 | 53
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Zinc finger protein 709 ZNF709 Tdark Transcription Factor 0.70 0.03 16
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
Lysine-specific demethylase 3A KDM3A Tchem Epigenetic -1.83544 74.7 253
Lysine-specific demethylase hairless HR Tbio Enzyme -1.13301 12.4 99
Double homeobox protein 4 DUX4 Tbio Non-IDG 0.00000 153
Transcription factor SOX-12 SOX12 Tbio Transcription Factor -0.86228 7.00 174
Lysine-specific demethylase 3B KDM3B Tbio Epigenetic -1.04920 11.3 286
Zinc finger protein 568 ZNF568 Tdark Transcription Factor 0.41 0.29 104
Trinucleotide repeat-containing gene 18 protein TNRC18 Tdark Non-IDG 0.95 0.08 20