Development Level

Tbio 8 | 11,445

IMPC Phenotype

decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
abnormal humerus morphology 1 | 11
abnormal seminal vesicle morph... 1 | 114
decreased lymphocyte cell numb... 1 | 83
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 7 | 11,493
lung cancer 5 | 4,740
Cancer 4 | 2,499
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
ovarian cancer 4 | 8,520
Breast cancer 3 | 3,578
medulloblastoma, large-cell 3 | 6,241
psoriasis 3 | 6,694
Adenoid Cystic Carcinoma 2 | 99
Carcinoma, Adenoid Cystic 2 | 99
Glioma 2 | 74
Polycystic ovary syndrome 2 | 360
adult high grade glioma 2 | 3,801
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
malignant mesothelioma 2 | 3,232
osteosarcoma 2 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
Abortion, Spontaneous 1 | 109
Acute Basophilic Leukemia 1 | 2
Adenocarcinoma of lung 1 | 142
Adenocarcinoma of lung (disorder) 1 | 60
Angiocentric glioma 1 | 2
Ankylosing spondylitis 1 | 140
Arthritis 1 | 290
Asthma 1 | 385
Astrocytoma, Pilocytic 1 | 3,081
Cardiomegaly 1 | 116
Cardiovascular system disease 1 | 246
Cockayne syndrome 1 | 60
Congenital myasthenic syndrome 4C 1 | 9
Cystoisosporiasis 1 | 5
Delirium 1 | 10
Dental caries 1 | 164
Dental fluorosis 1 | 20
Depressive disorder 1 | 409
Ectopic pregnancy 1 | 16
Embryo Loss 1 | 7
Female Urogenital Diseases 1 | 18
Female infertility 1 | 30
Hemolytic anemia 1 | 77
Infertility 1 | 188
Infertility, Female 1 | 28
Mental Depression 1 | 333
Mood disorder 1 | 14
Multiple Sclerosis 1 | 540
Multiple myeloma 1 | 1,332
Non-alcoholic Fatty Liver Disease 1 | 42
Ovarian small cell carcinoma 1 | 1
Peripheral vascular disease 1 | 87
Pick disease 1 | 1,894
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1 | 25
Sex cord-gonadal stromal tumor 1 | 2
Spontaneous abortion 1 | 113
Tuberculous salpingitis 1 | 1
Waldenstrons macroglobulinemia 1 | 765
Weight Loss 1 | 24
Weight decreased 1 | 103
acute T cell leukemia 1 | 17
adrenocortical carcinoma 1 | 1,428
astrocytic glioma 1 | 2,597
atypical teratoid / rhabdoid tumor 1 | 5,112
atypical teratoid/rhabdoid tumor 1 | 357
breast carcinoma 1 | 1,638
chronic rhinosinusitis 1 | 512
cutaneous lupus erythematosus 1 | 1,057
dermatomyositis 1 | 966
ductal carcinoma in situ 1 | 1,745
head and neck cancer 1 | 271
inflammatory breast cancer 1 | 286
interstitial cystitis 1 | 2,312
invasive ductal carcinoma 1 | 2,951
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
lung carcinoma 1 | 2,843
non primary Sjogren syndrome sicca 1 | 891
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
pancreatic cancer 1 | 2,398
pituitary cancer 1 | 1,972
posterior fossa group B ependymoma 1 | 416
primary Sjogren syndrome 1 | 735
progressive supranuclear palsy 1 | 676
sarcoidosis 1 | 370
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Transcription Factor 7 | 1,400
Non-IDG 1 | 12,091

GO Function

transcription factor activity,... 8 | 8
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leukemia inhibitory factor LIF Tbio Non-IDG -2.86943 538.7 413
Transcriptional activator Myb MYB Tbio Transcription Factor -2.97697 938.9 642
Myb-related protein B MYBL2 Tbio Transcription Factor -2.19738 169.0 289
Transcription termination factor 1 TTF1 Tbio Transcription Factor -1.46865 27.0 162
Cyclin-D-binding Myb-like transcription factor 1 DMTF1 Tbio Transcription Factor -1.39474 26.0 208
Cell division cycle 5-like protein CDC5L Tbio Transcription Factor -2.15843 139.9 212
snRNA-activating protein complex subunit 4 SNAPC4 Tbio Transcription Factor -0.99715 10.0 160
Myb-related protein A MYBL1 Tbio Transcription Factor -2.02812 104.7 156