Development Level

Tbio 50 | 11,445
Tchem 10 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
enlarged heart 4 | 210
abnormal heart morphology 2 | 162
decreased circulating calcium ... 2 | 36
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
increased circulating aspartat... 2 | 15
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal kidney morphology 1 | 65
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
decreased IgG1 level 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lactate dehydrogenas... 1 | 3
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total retina thickne... 1 | 4
preweaning lethality, incomple... 1 | 499
small spleen 1 | 19
small superior vagus ganglion 1 | 74

Disease

Carcinoma 39 | 11,493
Cancer 34 | 2,499
osteosarcoma 33 | 7,950
psoriasis 28 | 6,694
ovarian cancer 27 | 8,520
atypical teratoid / rhabdoid tumor 24 | 5,112
medulloblastoma, large-cell 23 | 6,241
lung cancer 22 | 4,740
glioblastoma 21 | 5,792
malignant mesothelioma 19 | 3,232
ependymoma 18 | 4,679
Breast cancer 17 | 3,578
group 3 medulloblastoma 15 | 4,104
primitive neuroectodermal tumor 15 | 3,035
diabetes mellitus 14 | 1,728
lung carcinoma 14 | 2,843
invasive ductal carcinoma 13 | 2,951
non-small cell lung cancer 13 | 2,890
ulcerative colitis 13 | 1,819
interstitial cystitis 12 | 2,312
pancreatic cancer 12 | 2,398
adult high grade glioma 11 | 3,801
colon cancer 11 | 1,478
lung adenocarcinoma 11 | 2,716
Autosomal recessive predisposition 9 | 1,442
acute quadriplegic myopathy 9 | 1,158
astrocytoma 9 | 1,146
breast carcinoma 9 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Congenital heart disease 8 | 93
Obesity 8 | 678
Polycystic ovary syndrome 8 | 360
cystic fibrosis 8 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
oligodendroglioma 8 | 2,850
primary pancreatic ductal adenocarcinoma 8 | 1,109
Bipolar Disorder 7 | 666
Breast Neoplasms 7 | 445
Cryptorchidism 7 | 296
Intellectual disability 7 | 1,016
Muscle hypotonia 7 | 571
Pick disease 7 | 1,894
aldosterone-producing adenoma 7 | 665
gastric carcinoma 7 | 807
group 4 medulloblastoma 7 | 1,855
pituitary cancer 7 | 1,972
subependymal giant cell astrocytoma 7 | 2,287
Cognitive delay 6 | 608
Dull intelligence 6 | 645
Epilepsy 6 | 792
Global developmental delay 6 | 608
Heart disease 6 | 306
Kidney cancer 6 | 2,613
Kidney disease 6 | 430
Low intelligence 6 | 645
Mammary Neoplasms 6 | 425
Mental Retardation 6 | 645
Mental and motor retardation 6 | 608
Mental deficiency 6 | 645
Osteoporosis 6 | 363
Poor school performance 6 | 645
Schizophrenia 6 | 1,160
Short stature 6 | 531
Tetralogy of Fallot 6 | 63
ductal carcinoma in situ 6 | 1,745
nephrosclerosis 6 | 333
sonic hedgehog group medulloblastoma 6 | 467
tuberculosis 6 | 2,010
Alzheimer's disease 5 | 658
Brain Ischemia 5 | 110
Carcinoma, Hepatocellular 5 | 228
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Diabetes Mellitus, Type 2 5 | 142
Down syndrome 5 | 499
Failure to gain weight 5 | 365
Hypertensive disease 5 | 292
Hypogonadism 5 | 173
Liver carcinoma 5 | 240
Liver disease 5 | 237
Patent ductus arteriosus 5 | 90
Pediatric failure to thrive 5 | 365
Rheumatoid arthritis 5 | 1,191
Seizures 5 | 596
Sensorineural Hearing Loss (disorder) 5 | 284
chronic lymphosyte leukemia 5 | 204
pediatric high grade glioma 5 | 1,064
Arthritis 4 | 290
Astrocytoma, Pilocytic 4 | 3,081
Hypertension 4 | 396
Lung disease 4 | 142
Multiple myeloma 4 | 1,332
Prostatic Neoplasms 4 | 495
Type 2 diabetes mellitus 4 | 272
Ventricular Septal Defects 4 | 119
astrocytic glioma 4 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
cutaneous lupus erythematosus 4 | 1,057
primary Sjogren syndrome 4 | 735
spina bifida 4 | 1,074

Tissue

Digestive Tract 61 | 17,369
Skin and soft tissues 59 | 17,230
Endocrine System 58 | 18,159
Male tissues 56 | 17,142
Female tissues 53 | 17,400
Blood and immune system 52 | 16,909
Nervous System 52 | 16,725
Urinary Tract 51 | 16,678
Liver and Pancreas 50 | 16,750
Respiratory system 50 | 16,393
Cardiovascular System 47 | 15,192

Target Family

Transcription Factor 53 | 1,400
Nuclear Receptor 5 | 48
Non-IDG 4 | 12,091

GO Function

transcription factor activity,... 62 | 62
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.05079 1139.0 397
Forkhead box protein C2 FOXC2 Tbio Transcription Factor -2.23435 187.0 419
Oligodendrocyte transcription factor 2 OLIG2 Tbio Transcription Factor -2.64017 420.5 368
Steroid hormone receptor ERR2 ESRRB Tchem Nuclear Receptor -1.95523 86.9 173
General transcription factor II-I repeat domain-containing protein 1 GTF2IRD1 Tbio Transcription Factor -1.74692 0.00000 281
Brachyury protein TBXT Tbio Transcription Factor -2.24737 158.4 337
Transcriptional activator protein Pur-alpha PURA Tbio Non-IDG -2.17708 158.7 170
Transcription factor GATA-5 GATA5 Tbio Transcription Factor -1.95925 86.1 183
POU domain, class 4, transcription factor 1 POU4F1 Tbio Transcription Factor -2.19846 154.8 107
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436