Development Level

Tbio 11 | 11,445
Tchem 4 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 2 | 220
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal skin morphology 1 | 50
abnormal tooth morphology 1 | 24
decreased bone mineral content 1 | 151
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
enlarged epididymis 1 | 31
enlarged heart 1 | 210
female infertility 1 | 60
increased bone mineral content 1 | 108
increased heart rate 1 | 23
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
male infertility 1 | 123
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
shortened RR interval 1 | 17

Disease

Carcinoma 13 | 11,493
ovarian cancer 11 | 8,520
medulloblastoma, large-cell 10 | 6,241
osteosarcoma 10 | 7,950
Breast cancer 8 | 3,578
Cancer 8 | 2,499
psoriasis 8 | 6,694
breast carcinoma 7 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung cancer 7 | 4,740
Pick disease 6 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
malignant mesothelioma 6 | 3,232
Obesity 5 | 678
Prostatic Neoplasms 5 | 495
adult high grade glioma 5 | 3,801
cystic fibrosis 5 | 1,696
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
lung adenocarcinoma 5 | 2,716
pituitary cancer 5 | 1,972
Alzheimer's disease 4 | 658
Liver neoplasms 4 | 130
Rheumatoid arthritis 4 | 1,191
atypical teratoid / rhabdoid tumor 4 | 5,112
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
ependymoma 4 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
primitive neuroectodermal tumor 4 | 3,035
Astrocytoma, Pilocytic 3 | 3,081
Atherosclerosis 3 | 291
Breast Neoplasms 3 | 445
Coronary artery disease 3 | 268
Glaucoma 3 | 239
Hyperinsulinism 3 | 133
Insulin Resistance 3 | 72
Mammary Neoplasms 3 | 425
Neoplasms 3 | 63
Schizophrenia 3 | 1,160
adrenocortical carcinoma 3 | 1,428
dermatomyositis 3 | 966
group 4 medulloblastoma 3 | 1,855
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
spina bifida 3 | 1,074
Acquired metabolic disease 2 | 336
Adenoma 2 | 167
Alzheimer Disease 2 | 83
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Bladder Neoplasm 2 | 112
Carcinoma, Hepatocellular 2 | 228
Congenital deafness 2 | 185
Corneal disease 2 | 31
Deafness 2 | 198
Depressive disorder 2 | 409
Disease Models, Animal 2 | 155
Disease Progression 2 | 136
Endometriosis 2 | 540
Hearing Loss, Partial 2 | 185
Heart disease 2 | 306
Hepatomegaly 2 | 285
Hypercholesterolemia 2 | 44
Hypertension 2 | 396
Infertility, Male 2 | 46
Inflammation 2 | 120
Liver carcinoma 2 | 240
Lung Neoplasms 2 | 232
Male infertility 2 | 206
Mental Depression 2 | 333
Myopathy 2 | 185
Neoplasm Invasiveness 2 | 161
Neuroblastoma 2 | 80
Osteoporosis 2 | 363
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Pneumonia 2 | 174
Prostate cancer 2 | 175
Reperfusion Injury 2 | 86
Sensorineural Hearing Loss (disorder) 2 | 284
Stomach Neoplasms 2 | 300
Urinary Bladder Neoplasms 2 | 114
Vascular disease 2 | 319
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
atypical teratoid/rhabdoid tumor 2 | 357
chronic rhinosinusitis 2 | 512
gastric carcinoma 2 | 807
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
periodontitis 2 | 293
primary pancreatic ductal adenocarcinoma 2 | 1,109
subependymal giant cell astrocytoma 2 | 2,287
substance-related disorder 2 | 162
tuberculosis 2 | 2,010

Tissue

Endocrine System 18 | 18,159
Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Female tissues 17 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Cardiovascular System 15 | 15,192

Target Family

Transcription Factor 9 | 1,400
Nuclear Receptor 4 | 48
Non-IDG 3 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634

GO Function

transcription coactivator bind... 18 | 18
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Aryl hydrocarbon receptor AHR Tchem Transcription Factor 0.00000 773
Forkhead box protein C1 FOXC1 Tbio Transcription Factor -2.28586 201.8 314
Circadian clock protein PASD1 PASD1 Tbio Non-IDG -1.11727 13.3 187
60S ribosomal protein L23 RPL23 Tbio Non-IDG -1.57812 38.1 118
Nuclear receptor subfamily 4 group A member 3 NR4A3 Tbio Nuclear Receptor -2.02752 112.7 289
Transcription factor A, mitochondrial TFAM Tbio Transcription Factor -2.72618 499.4 378
Telomerase reverse transcriptase TERT Tchem Enzyme -3.56910 3506.4 643
Zinc finger and BTB domain-containing protein 17 ZBTB17 Tbio Transcription Factor -1.57508 40.4 92
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610