Development Level

Tbio 10 | 11,445
Tclin 3 | 613
Tchem 1 | 1,598

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal heart morphology 1 | 162
abnormal response to new envir... 1 | 10
decreased circulating amylase ... 1 | 28
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
increased circulating chloride... 1 | 41
increased heart weight 1 | 62

Disease

Carcinoma 8 | 11,493
Astrocytoma, Pilocytic 6 | 3,081
glioblastoma 6 | 5,792
group 3 medulloblastoma 6 | 4,104
lung adenocarcinoma 6 | 2,716
medulloblastoma, large-cell 6 | 6,241
Breast cancer 5 | 3,578
Heart disease 5 | 306
Pick disease 5 | 1,894
atypical teratoid / rhabdoid tumor 5 | 5,112
diabetes mellitus 5 | 1,728
ependymoma 5 | 4,679
osteosarcoma 5 | 7,950
primitive neuroectodermal tumor 5 | 3,035
psoriasis 5 | 6,694
Cancer 4 | 2,499
Cardiomyopathy 4 | 116
Cardiomyopathy, Dilated 4 | 83
Cerebrovascular disease 4 | 238
Dilated cardiomyopathy 4 | 56
Familial isolated dilated cardiomyopathy 4 | 41
Hypertrophic Cardiomyopathy 4 | 117
LEFT VENTRICULAR NONCOMPACTION 10 4 | 40
LEFT VENTRICULAR NONCOMPACTION 8 4 | 40
Myopathy 4 | 185
adult high grade glioma 4 | 3,801
lung cancer 4 | 4,740
ovarian cancer 4 | 8,520
Alzheimer's disease 3 | 658
Amyloidosis 3 | 67
Amyotrophic lateral sclerosis 3 | 451
Aspergillosis 3 | 26
Autosomal recessive predisposition 3 | 1,442
Epilepsy 3 | 792
Hypertension 3 | 396
Idiopathic scoliosis 3 | 31
Long QT syndrome 1 3 | 20
Malignant hyperthermia 3 | 26
Multiple epiphyseal dysplasia 3 | 18
Otitis externa 3 | 10
Pertussis 3 | 20
Pseudoachondroplasia 3 | 14
Schizophrenia 3 | 1,160
Sporotrichosis 3 | 10
Supraventricular arrhythmia 3 | 4
Tetanus 3 | 68
Toxic encephalopathy 3 | 141
Ventricular arrhythmia 3 | 27
acute quadriplegic myopathy 3 | 1,158
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
Cardiomegaly 2 | 116
Cardiomyopathies 2 | 110
Creatine phosphokinase serum increased 2 | 110
Difficulty walking 2 | 28
Distal arthrogryposis 2 | 42
Elevated creatine kinase 2 | 110
Kidney cancer 2 | 2,613
Muscle biopsy shows dystrophic changes 2 | 39
Muscular dystrophy 2 | 75
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
limb-girdle muscular dystrophy 2 | 37
non-small cell lung carcinoma 2 | 317
oligodendroglioma 2 | 2,850
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Adducted thumb 1 | 22
Arthrogryposis 1 | 54
Atrophic 1 | 10
Atrophy 1 | 10
Congestive heart failure 1 | 113
DOID:2627 1 | 94
Death, Sudden, Cardiac 1 | 5
Disease Models, Animal 1 | 155
Dizziness 1 | 26
Endomyocardial Fibrosis 1 | 13
Eosinophilia 1 | 28
Flexion contracture 1 | 93
Flexion contracture of proximal interphalangeal joint 1 | 75
Flexion contractures of joints 1 | 93
Gaucher disease type 1 1 | 180
Infantile onset spinocerebellar ataxia 1 | 7
Joint stiffness 1 | 84
Lower limb atrophy 1 | 8
Lower limb muscle hypotrophy 1 | 8
Muscle atrophy, lower limb, distal 1 | 8
Muscle atrophy, proximal 1 | 11
Muscular atrophy 1 | 71
Myocardial Infarction 1 | 151
Overlapping fingers 1 | 10
Sudden Cardiac Death 1 | 29
Vertigo 1 | 29
cystic fibrosis and chronic rhinosinusitis 1 | 214
inflammatory breast cancer 1 | 286

Tissue

Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Nervous System 13 | 16,725
Respiratory system 13 | 16,393

Target Family

Non-IDG 11 | 12,091
Kinase 2 | 634
Enzyme 1 | 4,145

GO Function

titin binding 14 | 14
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calmodulin-2 CALM3 Tclin Non-IDG -3.59834 5859.5 0
Calmodulin-3 CALM3 Tclin Non-IDG -3.59140 5859.5 0
E3 ubiquitin-protein ligase TRIM63 TRIM63 Tbio Enzyme -2.29530 189.7 264
Ankyrin repeat domain-containing protein 2 ANKRD2 Tbio Non-IDG -1.49742 36.2 62
Obscurin OBSCN Tbio Kinase -1.77887 66.6 22
Ankyrin repeat domain-containing protein 23 ANKRD23 Tbio Non-IDG -1.55722 37.8 24
Calpain-3 CAPN3 Tbio Non-IDG -2.45065 293.3 110
Ankyrin repeat domain-containing protein 1 ANKRD1 Tbio Non-IDG -1.79794 62.3 159
Myosin-binding protein C, cardiac-type MYBPC3 Tbio Non-IDG -2.45618 287.6 139
Calcium/calmodulin-dependent protein kinase type II subunit delta CAMK2D Tchem Kinase -1.37613 16.9 229