Development Level

Tbio 3 | 10,625
Tchem 2 | 1,890
Tclin 1 | 602
Tdark 1 | 7,003

IMPC Term

abnormal craniofacial morpholo... 1 | 12
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal eyelid morphology 1 | 6
abnormal facial morphology 1 | 9
abnormal head shape 1 | 4
abnormal head size 1 | 1
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal thoracic vertebrae mo... 1 | 16
anophthalmia 1 | 20
cleft palate 1 | 6
craniofacial phenotype 1 | 9
decreased alpha-beta T cell nu... 1 | 12
decreased bone mineral content 1 | 157
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased rib number 1 | 59
decreased spleen weight 1 | 13
decreased threshold for audito... 1 | 32
embryonic lethality prior to t... 1 | 187
facial cleft 1 | 3
increased exploration in new e... 1 | 56
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
mydriasis 1 | 9
prenatal lethality prior to he... 1 | 64
preweaning lethality, complete... 1 | 633
short tibia 1 | 82
small adrenal glands 1 | 15

Disease

ovarian cancer 3 | 8,484
Breast cancer 2 | 3,094
Colorectal Neoplasms 2 | 217
Retinitis pigmentosa 2 | 153
atypical teratoid / rhabdoid tumor 2 | 4,369
esophageal adenocarcinoma 2 | 737
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
lung cancer 2 | 4,466
psoriasis 2 | 6,685
Acute myelomonocytic leukemia, FAB M4 1 | 1
Acute promyelocytic leukemia, FAB M3 1 | 10
Adenoma 1 | 165
Barrett's esophagus 1 | 183
Blindness 1 | 84
Blood pressure finding 1 | 56
Cancer 1 | 2,346
Carcinoma, Lewis Lung 1 | 1
Colorectal Cancer 1 | 47
Contact Dermatitis 1 | 80
Cysticercosis 1 | 12
Degenerative polyarthritis 1 | 93
Echinococcosis 1 | 28
Epilepsy 1 | 346
Glaucoma 1 | 134
Goiter 1 | 27
Hyperthyroidism 1 | 50
Hyperthyroxinemia 1 | 9
Hypothyroidism 1 | 89
Male infertility 1 | 170
Mesothelioma 1 | 40
Migraine 1 | 79
Myocardial Ischemia 1 | 169
Primary ciliary dyskinesia 1 | 73
Prostatic Neoplasms 1 | 471
Schistosomiasis 1 | 38
Systemic arterial pressure 1 | 56
Thyrotoxicosis 1 | 38
Vulvitis 1 | 5
acute quadriplegic myopathy 1 | 1,157
colon cancer 1 | 1,475
cystic fibrosis 1 | 1,665
diabetes mellitus 1 | 1,663
glioblastoma 1 | 5,572
group 3 medulloblastoma 1 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,988
lung carcinoma 1 | 2,844
malignant mesothelioma 1 | 3,162
osteosarcoma 1 | 7,933
posterior fossa group A ependymoma 1 | 1,511
spina bifida 1 | 1,064
tuberculosis 1 | 1,557
ulcerative colitis 1 | 2,087

Tissue

Blood and immune system 7 | 17,995
Digestive Tract 7 | 18,473
Endocrine System 7 | 18,512
Liver and Pancreas 7 | 18,136
Nervous System 7 | 18,561
Urinary Tract 7 | 18,444
Cardiovascular System 6 | 17,958
Female tissues 6 | 18,647
Male tissues 6 | 17,969
Respiratory system 6 | 17,484
Skin and soft tissues 6 | 18,115

Target Family

Non-IDG 4 | 11,971
Enzyme 3 | 4,146

GO Function

thioredoxin-disulfide reductas... 7 | 7
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoredoxin NXN Tbio Non-IDG -2.49829 323.4 88
Thioredoxin reductase 3 TXNRD3 Tchem Enzyme -1.63845 55.1 0
Thioredoxin domain-containing protein 2 TXNDC2 Tbio Non-IDG -0.72285 6.88 13
Nucleoredoxin-like protein 1 NXNL1 Tbio Non-IDG -1.09142 14.5 97
Nucleoredoxin-like protein 2 NXNL2 Tdark Non-IDG -0.41218 3.20 93
Thioredoxin reductase 1, cytoplasmic TXNRD1 Tclin Enzyme -2.21033 186.7 258
Thioredoxin reductase 2, mitochondrial TXNRD2 Tchem Enzyme -2.62707 446.4 151