Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal retina morphology 1 | 71
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
short tibia 1 | 97

Disease

Carcinoma 9 | 11,493
ovarian cancer 7 | 8,520
Cancer 6 | 2,499
glioblastoma 6 | 5,792
osteosarcoma 6 | 7,950
psoriasis 5 | 6,694
lung cancer 4 | 4,740
Astrocytoma, Pilocytic 3 | 3,081
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
subependymal giant cell astrocytoma 3 | 2,287
Arthritis, Rheumatoid 2 | 174
Depressive disorder 2 | 409
Mental Depression 2 | 333
Mulibrey nanism 2 | 13
Multiple myeloma 2 | 1,332
Rheumatoid arthritis 2 | 1,191
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
esophageal adenocarcinoma 2 | 737
malignant mesothelioma 2 | 3,232
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis 2 | 2,010
Aarskog syndrome 1 | 12
Acquired metabolic disease 1 | 336
Administration of Local Anesthetic Nerve Block 1 | 14
Adrenal Gland Neoplasms 1 | 11
Alcoholic Intoxication, Chronic 1 | 289
Animal Mammary Neoplasms 1 | 136
Autosomal dominant hypohidrotic ectodermal dysplasia syndrome (disorder) 1 | 3
Brain Injuries 1 | 65
Bronchiectasis 1 | 64
Bronchitis 1 | 43
CD40 deficiency 1 | 4
Carcinoma, Hepatocellular 1 | 228
Cardiomegaly 1 | 116
Cardiomyopathy, Dilated 1 | 83
Cell Transformation, Neoplastic 1 | 97
Cerebral Ischemia 1 | 37
Chromosome 17q11.2 deletion syndrome, 1.4Mb 1 | 15
Clostridium difficile colitis 1 | 12
Conscious sedation 1 | 10
Dyspnea 1 | 76
Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere 1 | 5
Exacerbation of asthma 1 | 11
Familial partial lipodystrophy 1 | 12
Fibrosis 1 | 44
Gastrointestinal system disease 1 | 54
Gilles de la Tourette syndrome 1 | 47
HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 1 1 | 5
HIV Infections 1 | 102
Heart Diseases 1 | 43
Heart failure 1 | 162
Herpes encephalitis 1 | 6
Hypertensive Emergencies 1 | 10
Hypertensive disorder 1 | 56
Hypohidrotic ectodermal dysplasia 1 | 15
Hypotension 1 | 82
Juvenile rheumatoid arthritis 1 | 111
Liver carcinoma 1 | 240
Liver diseases 1 | 87
Local anesthesia, by infiltration 1 | 14
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Melanoma 1 | 711
Mood Disorders 1 | 184
Multiple Sclerosis 1 | 540
Nasal congestion 1 | 21
Nasal discharge 1 | 24
Necrosis 1 | 53
Neoplasm Metastasis 1 | 168
Neoplastic Cell Transformation 1 | 89
Ocular hypertension 1 | 42
Open-angle glaucoma 1 | 27
Osteopetrosis 1 | 43
Osteoporosis 1 | 363
Panic disorder 1 | 61
Parkinson's disease 1 | 392
Pheochromocytoma 1 | 24
Prevention of Cerebral Thrombosis 1 | 29
Pulmonary emphysema 1 | 48
Retinitis pigmentosa 47 1 | 4
Rosacea 1 | 25
Skin cancer 1 | 469
Spasticity 1 | 26
Ventricular Dysfunction, Left 1 | 22
Wiskott-Aldrich syndrome 1 | 30
anaphylaxis 1 | 11
chorea-acanthocytosis 1 | 12
uncontrolled asthma 1 | 56

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 3 | 4,145
GPCR 1 | 408

GO Function

thioesterase binding 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TNF receptor-associated factor 4 TRAF4 Tbio Non-IDG -1.67380 54.4 234
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Alpha-2A adrenergic receptor ADRA2A Tclin GPCR -2.42160 261.4 232
TNF receptor-associated factor 5 TRAF5 Tbio Non-IDG -1.57449 33.9 177
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
HAUS augmin-like complex subunit 7 HAUS7 Tbio Non-IDG -0.50191 2.67 188
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.94674 87.1 452
ADP-ribosylation factor 6 ARF6 Tbio Enzyme -2.48917 350.7 310
TNF receptor-associated factor 2 TRAF2 Tbio Non-IDG -1.90485 75.1 549
TNF receptor-associated factor 3 TRAF3 Tbio Non-IDG -2.50034 309.0 374