Development Level

Tbio 54 | 11,651
Tdark 11 | 6,593
Tclin 3 | 612
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 8 | 979
increased lean body mass 3 | 172
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased bone mineral density 2 | 126
decreased circulating lactate ... 2 | 3
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased total body fat amoun... 2 | 134
small testis 2 | 58
small thymus 2 | 16
abnormal bone structure 1 | 187
abnormal embryo turning 1 | 31
abnormal kidney morphology 1 | 65
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal thymus morphology 1 | 7
alopecia 1 | 1
decreased IgE level 1 | 6
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased brain size 1 | 4
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged seminal vesicle 1 | 10
female infertility 1 | 60
hydroencephaly 1 | 14
increased circulating glucose ... 1 | 24
increased circulating serum al... 1 | 22
increased exploration in new e... 1 | 8
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
male infertility 1 | 123
mammalian phenotype 1 | 17
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 47 | 11,493
ovarian cancer 38 | 8,520
glioblastoma 33 | 5,792
osteosarcoma 33 | 7,950
medulloblastoma, large-cell 30 | 6,241
psoriasis 29 | 6,694
atypical teratoid / rhabdoid tumor 28 | 5,112
ependymoma 27 | 4,679
group 3 medulloblastoma 27 | 4,104
Astrocytoma, Pilocytic 23 | 3,081
oligodendroglioma 23 | 2,850
adult high grade glioma 21 | 3,801
astrocytic glioma 20 | 2,597
lung carcinoma 18 | 2,843
Pick disease 17 | 1,894
primitive neuroectodermal tumor 16 | 3,035
subependymal giant cell astrocytoma 13 | 2,287
malignant mesothelioma 12 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
lung cancer 10 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
pituitary cancer 10 | 1,972
tuberculosis 10 | 2,010
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
invasive ductal carcinoma 9 | 2,951
pancreatic cancer 9 | 2,398
Breast cancer 8 | 3,578
Kidney cancer 8 | 2,613
juvenile dermatomyositis 8 | 1,187
Hypomyelinating leukodystrophy 6 7 | 26
Schizophrenia 7 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
Alzheimer's disease 6 | 658
acute quadriplegic myopathy 6 | 1,158
astrocytoma 6 | 1,146
diabetes mellitus 6 | 1,728
ductal carcinoma in situ 6 | 1,745
group 4 medulloblastoma 6 | 1,855
non-small cell lung cancer 6 | 2,890
progressive supranuclear palsy 6 | 676
Multiple myeloma 5 | 1,332
Tetanus 5 | 68
dermatomyositis 5 | 966
non primary Sjogren syndrome sicca 5 | 891
primary pancreatic ductal adenocarcinoma 5 | 1,109
spina bifida 5 | 1,074
Autosomal recessive predisposition 4 | 1,442
Cerebellar Ataxia 4 | 304
Down syndrome 4 | 499
Griscelli syndrome 4 | 24
Intellectual disability 4 | 1,016
Liver cancer 4 | 604
Neurodegenerative disease 4 | 414
active ulcerative colitis 4 | 764
cystic fibrosis 4 | 1,696
pediatric high grade glioma 4 | 1,064
Amyotrophic lateral sclerosis 3 | 451
Bipolar Disorder 3 | 666
Botulism 3 | 24
Cognitive delay 3 | 608
Epilepsy 3 | 792
Global developmental delay 3 | 608
Mental and motor retardation 3 | 608
Neuropathy 3 | 261
Nystagmus 3 | 317
Peripheral Neuropathy 3 | 134
Rheumatoid arthritis 3 | 1,191
active Crohn's disease 3 | 922
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
fibroadenoma 3 | 559
gastric cancer 3 | 459
lung adenocarcinoma 3 | 2,716
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
pancreatic carcinoma 3 | 562
ulcerative colitis 3 | 1,819
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Dystonia 2 | 164
Dystonic disease 2 | 106
Failure to gain weight 2 | 365
Hepatomegaly 2 | 285
Highly variable severity 2 | 157
Hyperreflexia 2 | 209
Liver Cirrhosis, Experimental 2 | 769
Melanoma 2 | 711
Pediatric failure to thrive 2 | 365
Severe mental retardation (I.Q. 20-34) 2 | 99
Skin cancer 2 | 469
Variable expressivity 2 | 157
Waldenstrons macroglobulinemia 2 | 765
atypical teratoid/rhabdoid tumor 2 | 357
glioblastoma multiforme 2 | 142
head and neck cancer 2 | 271

Tissue

Endocrine System 66 | 18,159
Male tissues 66 | 17,142
Digestive Tract 65 | 17,369
Female tissues 65 | 17,400
Nervous System 65 | 16,725
Urinary Tract 65 | 16,678
Liver and Pancreas 63 | 16,750
Skin and soft tissues 63 | 17,230
Respiratory system 62 | 16,393
Blood and immune system 59 | 16,909
Cardiovascular System 57 | 15,192

Target Family

Non-IDG 60 | 12,091
Enzyme 4 | 4,145
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 344
Kinase 1 | 634

GO Function

syntaxin binding 69 | 69
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Alpha-taxilin TXLNA Tbio Non-IDG -1.08682 11.4 99
Biogenesis of lysosome-related organelles complex 1 subunit 6 BLOC1S6 Tbio Non-IDG -1.84171 67.9 109
Synaptotagmin-11 SYT11 Tbio Non-IDG -1.00759 12.5 125
Synaptotagmin-17 SYT17 Tbio Non-IDG -0.77330 6.07 106
Gamma-soluble NSF attachment protein NAPG Tbio Non-IDG -1.66116 45.2 127
Golgin subfamily A member 2 GOLGA2 Tbio Non-IDG -1.95809 83.3 241
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.65458 432.1 352
Vesicle-associated membrane protein 2 VAMP2 Tbio Non-IDG -2.53335 323.7 203
Tyrosine-protein phosphatase non-receptor type 2 PTPN2 Tchem Enzyme -2.53451 297.2 192