Development Level

Tbio 28 | 11,651
Tdark 9 | 6,593
Tchem 2 | 1,388

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal heart morphology 2 | 162
enlarged heart 2 | 210
increased circulating alkaline... 2 | 122
preweaning lethality, complete... 2 | 979
abnormal allantois morphology 1 | 8
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal heart looping 1 | 5
abnormal iris transilluminatio... 1 | 2
abnormal limb bud morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pharyngeal arch morph... 1 | 8
abnormal retina morphology 1 | 71
abnormal tail bud morphology 1 | 8
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased fasted circulating g... 1 | 65
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged testis 1 | 6
enlarged thymus 1 | 5
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased eosinophil cell numb... 1 | 11
pale yolk sac 1 | 25
pallor 1 | 34
small testis 1 | 58

Disease

Carcinoma 25 | 11,493
osteosarcoma 18 | 7,950
ependymoma 17 | 4,679
ovarian cancer 15 | 8,520
psoriasis 15 | 6,694
glioblastoma 14 | 5,792
lung carcinoma 12 | 2,843
medulloblastoma, large-cell 12 | 6,241
non-small cell lung cancer 12 | 2,890
adult high grade glioma 11 | 3,801
atypical teratoid / rhabdoid tumor 11 | 5,112
active Crohn's disease 10 | 922
interstitial cystitis 10 | 2,312
lung adenocarcinoma 10 | 2,716
lung cancer 10 | 4,740
pituitary cancer 10 | 1,972
tuberculosis 10 | 2,010
Breast cancer 9 | 3,578
pancreatic cancer 9 | 2,398
ulcerative colitis 9 | 1,819
active ulcerative colitis 8 | 764
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
invasive ductal carcinoma 7 | 2,951
malignant mesothelioma 7 | 3,232
astrocytic glioma 6 | 2,597
colon cancer 6 | 1,478
group 3 medulloblastoma 6 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Astrocytoma, Pilocytic 5 | 3,081
Atopic dermatitis 5 | 952
Autosomal recessive predisposition 5 | 1,442
Pick disease 5 | 1,894
Rheumatoid arthritis 5 | 1,191
breast carcinoma 5 | 1,638
cystic fibrosis 5 | 1,696
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,855
nasopharyngeal carcinoma 5 | 1,058
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
Endometriosis 4 | 540
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Schizophrenia 4 | 1,160
adrenocortical carcinoma 4 | 1,428
primitive neuroectodermal tumor 4 | 3,035
Bipolar Disorder 3 | 666
Cancer 3 | 2,499
Crohn's disease 3 | 321
Down syndrome 3 | 499
Hypoglycemia 3 | 152
Muscle hypotonia 3 | 571
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
diabetes mellitus 3 | 1,728
non primary Sjogren syndrome sicca 3 | 891
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676
urothelial carcinoma 3 | 318
Acquired metabolic disease 2 | 336
Amyotrophic lateral sclerosis 2 | 451
Asthma 2 | 385
Atherosclerosis 2 | 291
Babinski Reflex 2 | 100
Cholestasis 2 | 155
Cognitive delay 2 | 608
Colonic Neoplasms 2 | 142
Duchenne muscular dystrophy 2 | 601
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Hyperreflexia 2 | 209
Hypertrophic Cardiomyopathy 2 | 117
Melanoma 2 | 711
Mental and motor retardation 2 | 608
Microcephaly 2 | 166
Multiple myeloma 2 | 1,332
Myopathy 2 | 185
Oculocutaneous albinism 2 | 29
Pediatric failure to thrive 2 | 365
Sensorineural hearing loss 2 | 106
X-linked cerebral adrenoleukodystrophy 2 | 116
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
facioscapulohumeral dystrophy 2 | 288
fibroadenoma 2 | 559
gastric cancer 2 | 459
gastric carcinoma 2 | 807
hereditary spastic paraplegia 2 | 318
juvenile dermatomyositis 2 | 1,187
pancreatic carcinoma 2 | 562
periodontitis 2 | 293
sarcoidosis 2 | 370
spina bifida 2 | 1,074

Tissue

Endocrine System 39 | 18,159
Female tissues 39 | 17,400
Nervous System 37 | 16,725
Skin and soft tissues 37 | 17,230
Urinary Tract 37 | 16,678
Liver and Pancreas 36 | 16,750
Blood and immune system 35 | 16,909
Digestive Tract 35 | 17,369
Male tissues 35 | 17,142
Respiratory system 35 | 16,393
Cardiovascular System 32 | 15,192

Target Family

Transporter 37 | 473
Non-IDG 2 | 12,091

GO Function

symporter activity 39 | 39
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proton-coupled amino acid transporter 4 SLC36A4 Tbio Transporter -1.46987 30.6 45
Monocarboxylate transporter 3 SLC16A8 Tbio Transporter -1.52718 33.5 105
Vesicular glutamate transporter 3 SLC17A8 Tbio Transporter -2.00898 110.3 57
Sodium/potassium/calcium exchanger 5 SLC24A5 Tbio Transporter -1.63611 43.9 61
Solute carrier family 22 member 5 SLC22A5 Tbio Transporter -2.47467 297.1 113
Monocarboxylate transporter 14 SLC16A14 Tdark Transporter -0.76248 6.08 36
Monocarboxylate transporter 4 SLC16A3 Tchem Transporter -1.33148 17.9 161
Monocarboxylate transporter 11 SLC16A11 Tbio Transporter -0.83787 7.35 61
Sodium/bile acid cotransporter 7 SLC10A7 Tdark Transporter -0.46850 2.52 66
Solute carrier family 22 member 4 SLC22A4 Tbio Transporter -3.09928 1238.9 82