Development Level

Tbio 4 | 11,445
Tclin 1 | 613

Disease

Cancer 3 | 2,499
Waldenstrons macroglobulinemia 3 | 765
atypical teratoid / rhabdoid tumor 3 | 5,112
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
psoriasis 3 | 6,694
Adverse reaction to drug 2 | 61
Breast cancer 2 | 3,578
Carcinoma 2 | 11,493
Drug-Related Side Effects and Adverse Reactions 2 | 62
Hypersensitivity reaction type II disease 2 | 253
Multiple myeloma 2 | 1,332
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
astrocytoma 2 | 1,146
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
ovarian cancer 2 | 8,520
primary Sjogren syndrome 2 | 735
progressive supranuclear palsy 2 | 676
Acquired immunodeficiency syndrome 1 | 197
Adenocarcinoma of lung 1 | 142
Adenocarcinoma of lung (disorder) 1 | 60
Adenocarcinoma of pancreas 1 | 14
Alcoholic Intoxication, Chronic 1 | 289
Alopecia 1 | 115
Alzheimer's disease 1 | 658
Amyotrophic lateral sclerosis 1 | 451
Arthritis 1 | 290
Axonal neuropathy 1 | 27
Brain disease 1 | 96
Carcinoma, Hepatocellular 1 | 228
Chemical and Drug Induced Liver Injury 1 | 195
Cholestasis, Extrahepatic 1 | 25
Chromosomal Instability 1 | 8
Diarrhea 1 | 253
Disease Models, Animal 1 | 155
Down syndrome 1 | 499
Duchenne muscular dystrophy 1 | 601
Endometriosis 1 | 540
Esophageal Squamous Cell Carcinoma 1 | 77
Eumycotic mycetoma 1 | 3
Fever 1 | 138
Hereditary spherocytosis type 3 1 | 14
Hyperalgesia 1 | 83
Inflammation 1 | 120
Kidney cancer 1 | 2,613
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Liver carcinoma 1 | 240
Lung disease 1 | 142
Malignant tumor of ovary 1 | 25
Melanoma 1 | 711
Metastasis from malignant tumor of colon 1 | 8
Mucositis 1 | 29
Myocardial Infarction 1 | 151
Myocardial Ischemia 1 | 169
Myocardial Reperfusion Injury 1 | 37
Necrosis 1 | 53
Neoplasms 1 | 63
Neuralgia 1 | 20
Neutropenia 1 | 72
Pancreatitis 1 | 123
Peritonitis 1 | 43
Pick disease 1 | 1,894
Polycystic ovary syndrome 1 | 360
Pulmonary Fibrosis 1 | 106
Secondary malignant neoplasm of pancreas 1 | 10
Sepsis 1 | 24
Squamous cell carcinoma of esophagus 1 | 77
Systemic lupus erythematosus 1 | 194
Systemic scleroderma 1 | 60
Thrombocytopenia 1 | 197
Vaccinia 1 | 36
Vascular disease 1 | 319
Werner syndrome 1 | 29
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
colon cancer 1 | 1,478
hepatocellular carcinoma 1 | 547
interstitial cystitis 1 | 2,312
interstitial lung disease 1 | 298
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
pancreatic cancer 1 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
primary pancreatic ductal adenocarcinoma 1 | 1,109
primitive neuroectodermal tumor 1 | 3,035
sonic hedgehog group medulloblastoma 1 | 467
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Transcription Factor 2 | 1,400
Enzyme 1 | 4,145
Epigenetic 1 | 242
Non-IDG 1 | 12,091

GO Function

supercoiled DNA binding 5 | 5
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.61701 4015.4 248
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.19489 157.7 218
High mobility group protein B2 HMGB2 Tbio Transcription Factor -1.52510 34.5 267
PC4 and SFRS1-interacting protein PSIP1 Tbio Epigenetic -2.56190 391.2 150
High mobility group protein B1 HMGB1 Tbio Transcription Factor -3.05199 2190.4 1145