Development Level

Tbio 9 | 11,445
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal heart morphology 1 | 162
abnormal response to new envir... 1 | 10
decreased blood urea nitrogen ... 1 | 51
decreased circulating amylase ... 1 | 28
decreased circulating fructosa... 1 | 30
decreased grip strength 1 | 116
improved glucose tolerance 1 | 79
increased circulating chloride... 1 | 41
increased heart weight 1 | 62
thrombocytosis 1 | 27

Disease

Carcinoma 11 | 11,493
acute quadriplegic myopathy 6 | 1,158
Kidney cancer 5 | 2,613
lung adenocarcinoma 5 | 2,716
Hypertrophic Cardiomyopathy 4 | 117
Skin cancer 4 | 469
atypical teratoid / rhabdoid tumor 4 | 5,112
breast carcinoma 4 | 1,638
glioblastoma 4 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung carcinoma 4 | 2,843
psoriasis 4 | 6,694
Autosomal recessive predisposition 3 | 1,442
Breast cancer 3 | 3,578
Dilated cardiomyopathy 3 | 56
Distal arthrogryposis 3 | 42
Duchenne muscular dystrophy 3 | 601
Endometrial cancer 3 | 311
Primary cutaneous amyloidosis 3 | 29
ependymoma 3 | 4,679
limb-girdle muscular dystrophy 3 | 37
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
pediatric high grade glioma 3 | 1,064
Becker muscular dystrophy 2 | 191
Cardiomyopathy 2 | 116
Cardiomyopathy, Dilated 2 | 83
DOID:2627 2 | 94
Familial isolated dilated cardiomyopathy 2 | 41
Immune system cancer 2 | 140
Kidney disease 2 | 430
LEFT VENTRICULAR NONCOMPACTION 10 2 | 40
LEFT VENTRICULAR NONCOMPACTION 8 2 | 40
Liver cancer 2 | 604
Lymphoid leukemia 2 | 160
Melanoma 2 | 711
Multiple myeloma 2 | 1,332
astrocytic glioma 2 | 2,597
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 559
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
hereditary spastic paraplegia 2 | 318
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
limb girdle muscular dystrophy 2A 2 | 213
pancreatic cancer 2 | 2,398
Amyloidosis 1 | 67
Bushy eyebrows 1 | 49
Cardiomyopathy, Hypertrophic 1 | 24
Centronuclear myopathy 1 | 27
Chloracne 1 | 32
DOID:9917 1 | 31
Defective tooth enamel 1 | 31
Dubowitz syndrome 1 | 13
Dwarfism tall vertebrae 1 | 3
Dystrophic tooth enamel 1 | 31
Enamel abnormalities 1 | 31
Everted lower lip vermilion 1 | 54
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Gait, Drop Foot 1 | 24
Glycine encephalopathy 1 | 29
Hemolytic-Uremic Syndrome 1 | 30
Horizontal ribs 1 | 5
Hypertrichosis 1 | 46
Hypoplastic ischia 1 | 11
Hypoplastic pelvis 1 | 9
Hypoplastic pubic bone 1 | 7
Increased vertebral height 1 | 4
Infantile hypophosphatasia 1 | 5
Lymphoproliferative syndrome 1 | 58
Macroglobulinemia 1 | 18
Measles 1 | 22
Miller-McKusick-Malvaux-Syndrome (3M Syndrome) 1 | 3
Mulibrey nanism 1 | 13
Myasthenia gravis 1 | 23
Myofibrillar myopathy 5 1 | 5
Non-immune hydrops fetalis 1 | 11
POEMS syndrome 1 | 6
Pharyngitis 1 | 17
Polyneuropathy 1 | 64
Protruding lower lip 1 | 54
Pyoderma 1 | 4
Rheumatic fever 1 | 19
Rimmed vacuoles on biopsy 1 | 15
Scapular weakness 1 | 23
Short thorax 1 | 21
Short ulnae 1 | 24
Stomatitis 1 | 21
Subacute sclerosing panencephalitis 1 | 11
Thymoma 1 | 16
Tonsillitis 1 | 16
Toxic shock syndrome 1 | 28
ULNAR HYPOPLASIA 1 | 24
Winged scapula 1 | 23

Tissue

Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Urinary Tract 12 | 16,678
Blood and immune system 11 | 16,909
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Skin and soft tissues 11 | 17,230
Liver and Pancreas 10 | 16,750
Respiratory system 10 | 16,393
Cardiovascular System 9 | 15,192

Target Family

Non-IDG 11 | 12,091
Kinase 1 | 634

GO Function

structural molecule activity c... 12 | 12
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myomesin-1 MYOM1 Tbio Non-IDG -1.21420 16.8 127
Immunoglobulin superfamily member 22 IGSF22 Tdark Non-IDG 0.48 0.33 16
Neuroblast differentiation-associated protein AHNAK AHNAK Tbio Non-IDG -1.65508 52.1 119
Titin TTN Tbio Kinase -3.24415 1743.0 123
Myomesin-3 MYOM3 Tdark Non-IDG -0.34658 3.42 49
Myosin-binding protein H MYBPH Tbio Non-IDG -2.52998 324.4 146
Myosin-binding protein C, cardiac-type MYBPC3 Tbio Non-IDG -2.45618 287.6 139
Obscurin-like protein 1 OBSL1 Tbio Non-IDG -1.44861 27.3 8
Myomesin-2 MYOM2 Tbio Non-IDG -3.36742 2270.3 100
Myosin-binding protein C, slow-type MYBPC1 Tbio Non-IDG -1.29409 20.0 185