Development Level

Tbio 135 | 10,625
Tdark 84 | 7,003
Tchem 11 | 1,890
Tclin 2 | 602

IMPC Term

preweaning lethality, complete... 8 | 633
improved glucose tolerance 5 | 56
abnormal behavior 3 | 226
decreased fasted circulating g... 3 | 49
embryonic lethality prior to t... 3 | 187
increased mean corpuscular hem... 3 | 93
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
abnormal skin morphology 2 | 23
abnormal sleep behavior 2 | 63
decreased circulating calcium ... 2 | 33
decreased circulating free fat... 2 | 39
decreased circulating insulin ... 2 | 75
decreased circulating triglyce... 2 | 83
decreased hemoglobin content 2 | 53
decreased total body fat amoun... 2 | 186
embryonic lethality prior to o... 2 | 148
enlarged heart 2 | 111
male infertility 2 | 62
preweaning lethality, incomple... 2 | 260
short tibia 2 | 82
thrombocytopenia 2 | 46
abnormal behavioral response t... 1 | 52
abnormal gait 1 | 51
abnormal lung morphology 1 | 15
abnormal retina morphology 1 | 100
abnormal seminal vesicle morph... 1 | 47
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 17
cardiovascular system phenotyp... 1 | 35
decreased basophil cell number 1 | 11
decreased body length 1 | 108
decreased body weight 1 | 174
decreased cervical vertebrae n... 1 | 12
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased coping response 1 | 5
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased vertical activity 1 | 22
edema 1 | 11
embryonic growth retardation 1 | 28
enlarged uterus 1 | 3
hydrometra 1 | 13
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased NK T cell number 1 | 11
increased bone mineral content 1 | 92
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating potassiu... 1 | 31
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased or absent threshold ... 1 | 128
increased respiratory quotient 1 | 12
increased vertical activity 1 | 18
irregularly shaped pupil 1 | 7
polydactyly 1 | 22
prenatal lethality 1 | 16
shortened PQ interval 1 | 6
shortened PR interval 1 | 5
shortened RR interval 1 | 19
small spleen 1 | 11
small superior vagus ganglion 1 | 20
small testis 1 | 37
straub tail 1 | 26
thrombocytosis 1 | 23
tremors 1 | 34

Disease

psoriasis 113 | 6,685
ovarian cancer 85 | 8,484
medulloblastoma, large-cell 62 | 6,234
osteosarcoma 61 | 7,933
lung cancer 48 | 4,466
glioblastoma 47 | 5,572
atypical teratoid / rhabdoid tumor 44 | 4,369
non-small cell lung cancer 41 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 39 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 38 | 2,956
pancreatic cancer 38 | 2,300
lung adenocarcinoma 36 | 2,713
diabetes mellitus 35 | 1,663
Breast cancer 34 | 3,094
Atopic dermatitis 32 | 944
Carcinoma 32 | 2,147
ependymoma 32 | 2,514
malignant mesothelioma 32 | 3,162
lung carcinoma 31 | 2,844
pilocytic astrocytoma 31 | 3,086
invasive ductal carcinoma 30 | 2,950
pediatric high grade glioma 30 | 2,712
cystic fibrosis 29 | 1,665
oligodendroglioma 29 | 2,849
interstitial cystitis 28 | 2,299
primitive neuroectodermal tumor 28 | 3,031
Cancer 27 | 2,346
primary pancreatic ductal adenocarcinoma 27 | 1,271
subependymal giant cell astrocytoma 26 | 2,287
nasopharyngeal carcinoma 24 | 1,056
breast carcinoma 23 | 1,614
ductal carcinoma in situ 21 | 1,745
esophageal adenocarcinoma 21 | 737
pituitary cancer 20 | 1,972
acute quadriplegic myopathy 19 | 1,157
adult high grade glioma 19 | 2,148
atypical teratoid/rhabdoid tumor 19 | 1,095
astrocytic glioma 18 | 2,241
colon cancer 18 | 1,475
Multiple myeloma 17 | 1,327
posterior fossa group A ependymoma 17 | 1,511
group 3 medulloblastoma 16 | 2,254
spina bifida 16 | 1,064
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,795
ulcerative colitis 15 | 2,087
Amyotrophic Lateral Sclerosis 14 | 431
Duchenne muscular dystrophy 14 | 602
juvenile dermatomyositis 14 | 1,189
sonic hedgehog group medulloblastoma 14 | 1,482
Pick disease 13 | 1,893
active Crohn's disease 13 | 918
group 4 medulloblastoma 13 | 1,875
medulloblastoma 13 | 1,524
astrocytoma 12 | 1,493
dermatomyositis 12 | 933
posterior fossa group B ependymoma 12 | 1,530
adrenocortical carcinoma 11 | 1,427
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 499
gastric carcinoma 11 | 832
tuberculosis 11 | 1,557
non primary Sjogren syndrome sicca 10 | 840
Prostatic Neoplasms 9 | 471
Waldenstrons macroglobulinemia 9 | 765
aldosterone-producing adenoma 9 | 664
fibroadenoma 9 | 557
periodontitis 9 | 269
cutaneous lupus erythematosus 8 | 1,056
Alzheimer's disease 7 | 644
Down syndrome 7 | 548
Endometriosis 7 | 535
Mammary Neoplasms 7 | 410
Rheumatoid Arthritis 7 | 1,160
active ulcerative colitis 7 | 477
glioblastoma multiforme 7 | 347
inflammatory breast cancer 7 | 404
Cerebrovascular disease 6 | 231
Myopia 6 | 99
Osteoporosis 6 | 257
Palmoplantar keratosis 6 | 36
Polycystic Ovary Syndrome 6 | 332
Stomach Neoplasms 6 | 282
progressive supranuclear palsy 6 | 674
Alopecia 5 | 55
Atherosclerosis 5 | 275
Cardiomyopathy 5 | 110
Epidermolytic hyperkeratosis 5 | 13
Hypertension 5 | 287
Ichthyosis vulgaris 5 | 15
Keratosis 5 | 34
Liver disease 5 | 219
Monilethrix 5 | 16
Multiple Sclerosis 5 | 498
Myopathy 5 | 128
Neurodegenerative disease 5 | 383
Squamous cell carcinoma 5 | 94
interstitial lung disease 5 | 291
limb girdle muscular dystrophy 2A 5 | 156
pancreatic carcinoma 5 | 567
Schizophrenia 4 | 501

Tissue

Endocrine System 205 | 18,512
Female tissues 205 | 18,647
Skin and soft tissues 205 | 18,115
Digestive Tract 204 | 18,473
Nervous System 204 | 18,561
Urinary Tract 198 | 18,444
Liver and Pancreas 194 | 18,136
Blood and immune system 193 | 17,995
Cardiovascular System 192 | 17,958
Male tissues 188 | 17,969
Respiratory system 180 | 17,484

Target Family

Non-IDG 223 | 11,971
Enzyme 8 | 4,146
Kinase 1 | 634

GO Function

structural molecule activity 232 | 232
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Keratin, type II cytoskeletal 3 KRT3 Tbio Non-IDG -2.12849 126.8 100
Neurofilament heavy polypeptide NEFH Tbio Non-IDG -2.73883 563.3 681
Desmoplakin DSP Tbio Non-IDG -2.90088 786.5 167
Keratin, type II cytoskeletal 74 KRT74 Tbio Non-IDG -2.22050 159.7 35
Laminin subunit alpha-2 LAMA2 Tbio Non-IDG -2.48634 321.9 131
Fibrinogen alpha chain FGA Tbio Non-IDG -2.84597 716.2 457
MAP7 domain-containing protein 3 MAP7D3 Tbio Non-IDG -0.92082 8.05 8
Endogenous retrovirus group K member 9 Gag polyprotein ERVK-9 Tdark Non-IDG 0.00000 0
Endogenous retrovirus group K member 7 Pol protein ERVK-7 Tdark Enzyme 0.00000 0
Endogenous retrovirus group K member 7 Gag polyprotein ERVK-7 Tdark Non-IDG 0.00000 0